Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Megan J. Maher"'
Autor:
Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
WalKR is an essential two-component regulator that controls peptidoglycan synthesis in the human pathogen Staphylococcus aureus. Here, the authors provide biochemical, structural, and functional evidence supporting that the binding of a zinc ion inhi
Externí odkaz:
https://doaj.org/article/8c79c77e7e1c43c2b593eb5939e70c11
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 6983 (2020)
Complex IV (cytochrome c oxidase; COX) is the terminal complex of the mitochondrial electron transport chain. Copper is essential for COX assembly, activity, and stability, and is incorporated into the dinuclear CuA and mononuclear CuB sites. Multipl
Externí odkaz:
https://doaj.org/article/d6185e04b805475987ec32f357b3bd21
Publikováno v:
Bioscience Reports, Vol 34, Iss 6, p e00158 (2014)
GDP release from GTPases is usually extremely slow and is in general assisted by external factors, such as association with guanine exchange factors or membrane-embedded GPCRs (G protein-coupled receptors), which accelerate the release of GDP by seve
Externí odkaz:
https://doaj.org/article/8dd2d17cd62f4aef99fd6ae8e3805f96
Autor:
Sanjeedha S. M. Mubarak, Tess R. Malcolm, Hamish G. Brown, Eric Hanssen, Megan J. Maher, Gawain McColl, Guy N. L. Jameson
Publikováno v:
Biochemistry. 62:1484-1496
Publikováno v:
Acta Crystallographica Section D Structural Biology. 79:345-352
The arsenite oxidase (AioAB) from Pseudorhizobium banfieldiae sp. strain NT-26 catalyzes the oxidation of arsenite to arsenate and transfers electrons to its cognate electron acceptor cytochrome c 552 (cytc 552). This activity underpins the ability o
Autor:
Nilakhi Poddar, Shadi Maghool, Consuelo Badilla, Megan J. Maher, Thomas H. Osborne, Joanne M. Santini
Publikováno v:
Biochemistry. 60:465-476
The anaerobic bacterium Chrysiogenes arsenatis respires using the oxyanion arsenate (AsO43-) as the terminal electron acceptor, where it is reduced to arsenite (AsO33-) while concomitantly oxidizing various organic (e.g., acetate) electron donors. Th
Autor:
Oliver P. Ernst, Megan J. Maher
Publikováno v:
Current Opinion in Structural Biology. 69:vi-viii
Autor:
Erin B. Brazel, Aimee Tan, Stephanie L. Neville, Amy R. Iverson, Saumya R. Udagedara, Bliss A. Cunningham, Mwilye Sikanyika, David M.P. De Oliveira, Bernhard Keller, Lisa Bohlmann, Ibrahim M. El-Deeb, Katherine Ganio, Bart A. Eijkelkamp, Alastair G. McEwan, Mark von Itzstein, Megan J. Maher, Mark J. Walker, Jason W. Rosch, Christopher A. McDevitt
Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a4bec1a517e42f565efbfd3b08acdd
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Intracellular copper (Cu) in eukaryotic organisms is regulated by homeostatic systems, which rely on the activities of soluble metallochaperones that participate in Cu exchange through highly tuned protein-protein interactions. Recently, the human en
Autor:
Katherine Ganio, Andrew J. Hayes, Norimichi Nomura, Christopher A. McDevitt, Alex Carey Hulyer, Stephen J. Fairweather, Megan J. Maher, Tess R. Malcolm, Jacinta A. Watts, Aaron P. McGrath, Megan L. O'Mara, So Iwata, Jennie Sjöhamn, Stephanie L. Neville, Mark R. Davies, Hugo MacDermott-Opeskin
Publikováno v:
Science Advances
Bacterial manganese import is achieved by unique architectural features that are conserved across the kingdoms of life.
Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC) permeases serve as the primary imp
Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC) permeases serve as the primary imp