Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Megan J. Maher"'
Autor:
Ian R. Monk, Nausad Shaikh, Stephanie L. Begg, Mike Gajdiss, Liam K. R. Sharkey, Jean Y. H. Lee, Sacha J. Pidot, Torsten Seemann, Michael Kuiper, Brit Winnen, Rikki Hvorup, Brett M. Collins, Gabriele Bierbaum, Saumya R. Udagedara, Jacqueline R. Morey, Neha Pulyani, Benjamin P. Howden, Megan J. Maher, Christopher A. McDevitt, Glenn F. King, Timothy P. Stinear
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
WalKR is an essential two-component regulator that controls peptidoglycan synthesis in the human pathogen Staphylococcus aureus. Here, the authors provide biochemical, structural, and functional evidence supporting that the binding of a zinc ion inhi
Externí odkaz:
https://doaj.org/article/8c79c77e7e1c43c2b593eb5939e70c11
Autor:
Sanjeedha S. M. Mubarak, Tess R. Malcolm, Hamish G. Brown, Eric Hanssen, Megan J. Maher, Gawain McColl, Guy N. L. Jameson
Publikováno v:
Biochemistry. 62:1484-1496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::115ae85196c0c4cc2f60284701234138
https://doi.org/10.1021/acs.biochem.3c00005
https://doi.org/10.1021/acs.biochem.3c00005
Publikováno v:
Acta Crystallographica Section D Structural Biology. 79:345-352
The arsenite oxidase (AioAB) from Pseudorhizobium banfieldiae sp. strain NT-26 catalyzes the oxidation of arsenite to arsenate and transfers electrons to its cognate electron acceptor cytochrome c 552 (cytc 552). This activity underpins the ability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::230ae14a31cf798704a2a69864fe49af
https://doi.org/10.1107/s2059798323002103
https://doi.org/10.1107/s2059798323002103
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 6983 (2020)
Complex IV (cytochrome c oxidase; COX) is the terminal complex of the mitochondrial electron transport chain. Copper is essential for COX assembly, activity, and stability, and is incorporated into the dinuclear CuA and mononuclear CuB sites. Multipl
Externí odkaz:
https://doaj.org/article/d6185e04b805475987ec32f357b3bd21
Autor:
Nilakhi Poddar, Shadi Maghool, Consuelo Badilla, Megan J. Maher, Thomas H. Osborne, Joanne M. Santini
Publikováno v:
Biochemistry. 60:465-476
The anaerobic bacterium Chrysiogenes arsenatis respires using the oxyanion arsenate (AsO43-) as the terminal electron acceptor, where it is reduced to arsenite (AsO33-) while concomitantly oxidizing various organic (e.g., acetate) electron donors. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c899da8caa2635bc475105d8f602c8d3
https://doi.org/10.1021/acs.biochem.0c00555
https://doi.org/10.1021/acs.biochem.0c00555
Autor:
Oliver P. Ernst, Megan J. Maher
Publikováno v:
Current Opinion in Structural Biology. 69:vi-viii
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea386a5ed59194c0022d485ed4756fe5
https://doi.org/10.1016/j.sbi.2021.06.014
https://doi.org/10.1016/j.sbi.2021.06.014
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Intracellular copper (Cu) in eukaryotic organisms is regulated by homeostatic systems, which rely on the activities of soluble metallochaperones that participate in Cu exchange through highly tuned protein-protein interactions. Recently, the human en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ee2e00d127097fc12ad1278501d35b
http://link.springer.com/article/10.1038/s41598-020-60953-z
http://link.springer.com/article/10.1038/s41598-020-60953-z
Autor:
Erin B. Brazel, Aimee Tan, Stephanie L. Neville, Amy R. Iverson, Saumya R. Udagedara, Bliss A. Cunningham, Mwilye Sikanyika, David M.P. De Oliveira, Bernhard Keller, Lisa Bohlmann, Ibrahim M. El-Deeb, Katherine Ganio, Bart A. Eijkelkamp, Alastair G. McEwan, Mark von Itzstein, Megan J. Maher, Mark J. Walker, Jason W. Rosch, Christopher A. McDevitt
Streptococcus pneumoniae is the primary cause of community-acquired bacterial pneumonia with rates of penicillin and multidrug-resistance exceeding 80% and 40%, respectively. The innate immune response generates a variety of antimicrobial agents to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a4bec1a517e42f565efbfd3b08acdd
Autor:
Aaron P McGrath, Elise L Laming, G Patricia Casas Garcia, Marc Kvansakul, J Mitchell Guss, Jill Trewhella, Benoit Calmes, Paul V Bernhardt, Graeme R Hanson, Ulrike Kappler, Megan J Maher
Publikováno v:
eLife, Vol 4 (2015)
Interprotein electron transfer underpins the essential processes of life and relies on the formation of specific, yet transient protein-protein interactions. In biological systems, the detoxification of sulfite is catalyzed by the sulfite-oxidizing e
Externí odkaz:
https://doaj.org/article/295666060edd460ba12dad15e6907a1a
Autor:
Katherine Ganio, Andrew J. Hayes, Norimichi Nomura, Christopher A. McDevitt, Alex Carey Hulyer, Stephen J. Fairweather, Megan J. Maher, Tess R. Malcolm, Jacinta A. Watts, Aaron P. McGrath, Megan L. O'Mara, So Iwata, Jennie Sjöhamn, Stephanie L. Neville, Mark R. Davies, Hugo MacDermott-Opeskin
Publikováno v:
Science Advances
Bacterial manganese import is achieved by unique architectural features that are conserved across the kingdoms of life.
Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC) permeases serve as the primary imp
Metal ions are essential for all forms of life. In prokaryotes, ATP-binding cassette (ABC) permeases serve as the primary imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325083886c53aa322f6fb09ed239abe3
http://hdl.handle.net/2433/265288
http://hdl.handle.net/2433/265288