Zobrazeno 1 - 10 of 146 pro vyhledávání: '"Megan J Wallace"'
1
Akademický článek
Betamethasone improved near‐term neonatal lamb lung maturation in experimental maternal asthma
Autor: Joshua L. Robinson, Andrea J. Roff, Sarah J. Hammond, Jack R. T. Darby, Ashley S. Meakin, Stacey L. Holman, Andrew Tai, Tim J. M. Moss, Catherine G. Dimasi, Sarah M. Jesse, Michael D. Wiese, Andrew N. Davies, Beverly S. Muhlhausler, Robert J. Bischof, Megan J. Wallace, Vicki L. Clifton, Janna L. Morrison, Michael J. Stark, Kathryn L. Gatford
Publikováno v: Experimental Physiology, Vol 109, Iss 11, Pp 1967-1979 (2024)
Abstract Maternal asthma is associated with increased rates of neonatal lung disease, and fetuses from asthmatic ewes have fewer surfactant‐producing cells and lower surfactant‐protein B gene (SFTPB) expression than controls. Antenatal betamethas
Externí odkaz: https://doaj.org/article/9638ec5be75e4576afa102657005a265
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2
Akademický článek
Changes in positive end-expiratory pressure alter the distribution of ventilation within the lung immediately after birth in newborn rabbits.
Autor: Marcus J Kitchen, Melissa L Siew, Megan J Wallace, Andreas Fouras, Robert A Lewis, Naoto Yagi, Kentaro Uesugi, Arjan B Te Pas, Stuart B Hooper
Publikováno v: PLoS ONE, Vol 9, Iss 4, p e93391 (2014)
Current recommendations suggest the use of positive end-expiratory pressures (PEEP) to assist very preterm infants to develop a functional residual capacity (FRC) and establish gas exchange at birth. However, maintaining a consistent PEEP is difficul
Externí odkaz: https://doaj.org/article/30094a393c4348cdac2c7195065027a7
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3
Akademický článek
Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease.
Autor: Georgina Caruana, Peter G Farlie, Adam H Hart, Stefan Bagheri-Fam, Megan J Wallace, Michael S Dobbie, Christopher T Gordon, Kerry A Miller, Belinda Whittle, Helen E Abud, Ruth M Arkell, Timothy J Cole, Vincent R Harley, Ian M Smyth, John F Bertram
Publikováno v: PLoS ONE, Vol 8, Iss 3, p e55429 (2013)
Mice harbouring gene mutations that cause phenotypic abnormalities during organogenesis are invaluable tools for linking gene function to normal development and human disorders. To generate mouse models harbouring novel alleles that are involved in o
Externí odkaz: https://doaj.org/article/4ef49950460e4f1d88f053a4f9e96464
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5
Akademický článek
Expired CO2 levels indicate degree of lung aeration at birth.
Autor: Stuart B Hooper, Andreas Fouras, Melissa L Siew, Megan J Wallace, Marcus J Kitchen, Arjan B te Pas, Claus Klingenberg, Robert A Lewis, Peter G Davis, Colin J Morley, Georg M Schmölzer
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e70895 (2013)
As neonatal resuscitation critically depends upon lung aeration at birth, knowledge of the progression of this process is required to guide ongoing care. We investigated whether expired CO2 (ECO2) levels indicate the degree of lung aeration immediate
Externí odkaz: https://doaj.org/article/c105429c0fd147ad906ffae278ec4165
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6
Akademický článek
High bias gas flows increase lung injury in the ventilated preterm lamb.
Autor: Katinka P Bach, Carl A Kuschel, Stuart B Hooper, Jean Bertram, Sue McKnight, Shirley E Peachey, Valerie A Zahra, Sharon J Flecknoe, Mark H Oliver, Megan J Wallace, Frank H Bloomfield
Publikováno v: PLoS ONE, Vol 7, Iss 10, p e47044 (2012)
BACKGROUND: Mechanical ventilation of preterm babies increases survival but can also cause ventilator-induced lung injury (VILI), leading to the development of bronchopulmonary dysplasia (BPD). It is not known whether shear stress injury from gases f
Externí odkaz: https://doaj.org/article/2afa90d408ac4bd2a94bbc93f87077ee
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7
Effect of prenatal diaphragmatic hernia on pulmonary arterial morphology
Autor: Andrew V. Stainsby, Philip L. J. DeKoninck, Kelly J. Crossley, Alison Thiel, Megan J. Wallace, James T. Pearson, Aidan J. Kashyap, Michelle K. Croughan, Beth A. Allison, Ryan Hodges, Marta Thio, Andreas W. Flemmer, Erin V. McGillick, Arjan B. te Pas, Stuart B. Hooper, Marcus J. Kitchen
Publikováno v: Anatomical Record. John Wiley & Sons Inc.
Congenital diaphragmatic hernia (CDH) is a major cause of severe lung hypoplasia and pulmonary hypertension in the newborn. While the pulmonary hypertension is thought to result from abnormal vascular development and arterial vasoreactivity, the anat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b015c3bde07729902ef3938299bf5b7
https://pure.eur.nl/en/publications/a4fd8440-13fd-4013-9f02-ac38548574b5
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