Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Megan Groff"'
Autor:
Danhua Zhang, Keith P. Gates, Lindsey Barske, Guangliang Wang, Joseph J. Lancman, Xin-Xin I. Zeng, Megan Groff, Kasper Wang, Michael J. Parsons, J. Gage Crump, P. Duc Si Dong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell l
Externí odkaz:
https://doaj.org/article/9a869d75f80549c8a2ff75e1bc7269a8
Autor:
Lindsey Barske, P. Duc Si Dong, Guangliang Wang, Xin-Xin I. Zeng, Michael J. Parsons, Megan Groff, Danhua Zhang, Kasper S. Wang, Joseph J. Lancman, J. Gage Crump, Keith P. Gates
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Liver duct paucity is characteristic of children born with Alagille Syndrome (ALGS), a disease associated with JAGGED1 mutations. Here, we report that zebrafish embryos with compound homozygous mutations in two Notch ligand genes, jagged1b (jag1b) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1071e3e0edc7f0d982d034fe67797ed
https://doi.org/10.1038/s41467-017-00666-6
https://doi.org/10.1038/s41467-017-00666-6
Autor:
Nirmala Mavila, Kasper S. Wang, Pranavkumar Shivakumar, Megan Groff, Allison Wu, Katrina Mak, Marie V. Nguyen, Sarah Utley, Larry Wang, Shengmei Zhou, Christopher Vendyres, David James, Kinji Asahina
Publikováno v:
Hepatology (Baltimore, Md.). 60(3)
Biliary atresia (BA), the most common cause of end-stage liver disease and the leading indication for pediatric liver transplantation, is associated with intrahepatic ductular reactions within regions of rapidly expanding periportal biliary fibrosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab3b48d3ecc0a6c149146b073f0500d
https://pubmed.ncbi.nlm.nih.gov/24798639
https://pubmed.ncbi.nlm.nih.gov/24798639