Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Megan Goudie"'
Autor:
Nishi Karunasinghe, Tsion Zewdu Minas, Bo-Ying Bao, Arier Lee, Alice Wang, Shuotun Zhu, Jonathan Masters, Megan Goudie, Shu-Pin Huang, Frank J. Jenkins, Lynnette R. Ferguson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract It is being debated whether prostate-specific antigen (PSA)-based screening effectively reduces prostate cancer mortality. Some of the uncertainty could be related to deficiencies in the age-based PSA cut-off thresholds used in screening. Cu
Externí odkaz:
https://doaj.org/article/ac887caa3c184007ba8d3136083267a8
Autor:
Nishi Karunasinghe, Eva Symes, Amy Gamage, Alice Wang, Pam Murray, Shuotun Zhu, Megan Goudie, Jonathan Masters, Lynnette R Ferguson
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217373 (2019)
IntroductionAldo-keto reductase 1C3 (AKR1C3) is known for multiple functions including its catalytic activity towards producing extra-testicular androgen. The present study is towards understanding interaction between biological, lifestyle and geneti
Externí odkaz:
https://doaj.org/article/2863d6f5e91a4d71bdc10c8d79b1d3fc
Autor:
Nishi Karunasinghe, Stefan Ambs, Alice Wang, Wei Tang, Shuotun Zhu, Tiffany H Dorsey, Megan Goudie, Jonathan G Masters, Lynnette R Ferguson
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199122 (2018)
INTRODUCTION:The prostate-specific antigen (PSA) based prostate cancer (PC) screening is currently being debated. The current assessment is to understand the variability of detecting high-risk PC in a NZ cohort in comparison to a US cohort with bette
Externí odkaz:
https://doaj.org/article/c774758adc4349d98f731c54dab67880
Autor:
Karen S. Bishop, Dug Yeo Han, Nishi Karunasinghe, Megan Goudie, Jonathan G. Masters, Lynnette R. Ferguson
Publikováno v:
PeerJ, Vol 4, p e1731 (2016)
Background. Prostate cancer makes up approximately 15% of all cancers diagnosed in men in developed nations and approximately 4% of cases in developing nations. Although it is clear that prostate cancer has a genetic component and single nucleotide p
Externí odkaz:
https://doaj.org/article/4b5734ff10a34b58b084e0f37b7f5f40
Autor:
Lynnette R. Ferguson, Shuotun Zhu, Alice Wang, Megan Goudie, Arier Lee, Bo-Ying Bao, Nishi Karunasinghe, Tsion Z. Minas, Frank J. Jenkins, Shu-Pin Huang, Jonathan Masters
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Introduction- It is being debated whether prostate-specific antigen (PSA)-based screening effectively reduces prostate cancer mortality. Some of the uncertainty could be related to deficiencies in the age-based PSA cut-off thresholds used in screenin
Autor:
Alice Wang, Chi Hsiu-Juei Kao, Ajit Narayanan, Megan Goudie, Lynnette R. Ferguson, Mohanraj Krishnan, Venkatesh Vaidyanathan, Shuotun Zhu, Karen S. Bishop, Vijay Naidu, Jonathan Masters, Radha Pallati, Gareth Marlow, Anower Jabed, Nishi Karunasinghe, Phillip Shepherd
Publikováno v:
Molecular BioSystems. 13:681-698
Prostate cancer is one of the most significant health concerns for men worldwide. Numerous researchers carrying out molecular diagnostics have indicated that genetic interactions with biological and behavioral factors play an important role in the ov
Autor:
Tiffany H. Dorsey, Wei Tang, Lynnette R. Ferguson, Jonathan Masters, Alice Wang, Megan Goudie, Shuotun Zhu, Nishi Karunasinghe, Stefan Ambs
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199122 (2018)
INTRODUCTION:The prostate-specific antigen (PSA) based prostate cancer (PC) screening is currently being debated. The current assessment is to understand the variability of detecting high-risk PC in a NZ cohort in comparison to a US cohort with bette
Autor:
Megan Goudie, Alice Wang, Eva Symes, Jonathan Masters, Pam Murray, Shuotun Zhu, Lynnette R. Ferguson, Nishi Karunasinghe, Amy Gamage
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217373 (2019)
PLoS ONE
PLoS ONE
IntroductionAldo-keto reductase 1C3 (AKR1C3) is known for multiple functions including its catalytic activity towards producing extra-testicular androgen. The present study is towards understanding interaction between biological, lifestyle and geneti
Autor:
Nishi Karunasinghe, Alice Wang, Megan Goudie, Katja Lange, Karen S. Bishop, Dug Yeo Han, Lynnette R. Ferguson, Jonathan Masters, Shuotun Zhu
Publikováno v:
Current Pharmacogenomics and Personalized Medicine. 11:22-30
Autor:
Katja Lange, Alice Wang, Yifei Zhu, Nishi Karunasinghe, Justin W L Keogh, Shuotun Zhu, Michael Holmes, Lynnette R. Ferguson, Jonathan Masters, Dug Yeo Han, Stephanie Ellett, Benji Benjamin, Megan Goudie
Publikováno v:
BMC Urology
Background Androgen deprivation therapy (ADT) is an effective palliation treatment in men with advanced prostate cancer (PC). However, ADT has well documented side effects that could alter the patient’s health-related quality of life (HRQoL). The c