Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Megan G. Pino"'
Autor:
Kelly A. Rich, Megan G. Pino, Mehmet E. Yalvac, Ashley Fox, Hallie Harris, Maria H.H. Balch, W. David Arnold, Stephen J. Kolb
Publikováno v:
Neurobiology of Disease, Vol 182, Iss , Pp 106148- (2023)
Kinesin family member 5A (KIF5A) is an essential, neuron-specific microtubule-associated motor protein responsible for the anterograde axonal transport of various cellular cargos. Loss of function variants in the N-terminal, microtubule-binding domai
Externí odkaz:
https://doaj.org/article/cda27b4962784d7c8318bfefea38a90e
Publikováno v:
Biomarker Insights, Vol 16 (2021)
The availability of disease modifying therapies for spinal muscular atrophy (SMA) has created an urgent need to identify clinically meaningful biomarkers. Biomarkers present a means to measure and evaluate neurological disease across time. Changes in
Externí odkaz:
https://doaj.org/article/f1527f418a2d4bbf833ccb2dfd79efb1
Autor:
Raphael A. Malbrue, Lori Mattox, Stephen J. Kolb, Charlotte J. Sumner, Jessica Russo, Kelly A. Rich, Megan G. Pino, Patrick L. Heilman, Christopher G. Wier, Lingling Kong, Elizabeth Keckley, Anthony B. Reynolds, Amy Knapp, Catalin S. Buhimschi
Publikováno v:
Gene Ther
Numerous pediatric neurogenetic diseases may be optimally treated by in utero gene therapy (IUGT); but advancing such treatments requires animal models that recapitulate developmental physiology relevant to humans. One disease that could benefit from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b849da8aafad37f4d434196f7e736d
https://europepmc.org/articles/PMC10216882/
https://europepmc.org/articles/PMC10216882/
Autor:
Jerry Reynolds, Stephen J. Kolb, W. David Arnold, Gary Brent Sterling, Kelly A. Rich, Kristina M Kelly, Tristan Weaver, Mathew Linsenmayer, Sarah Heintzman, Amy Bartlett, Megan G. Pino, Kiran Rajneesh, Marco Tellez, Steven Severyn, Ashley Fox, Mehmet Emir Yalvaç, Bakri Elsheikh
Publikováno v:
Journal of neuromuscular diseases. 9(1)
Objective: To retrospectively evaluate the utility of serum and cerebrospinal fluid (CSF) levels of neurofilament light chain (NfL) and phosphorylated neurofilament heavy chain (pNfH) as biomarkers for spinal muscular atrophy (SMA) progression and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c66f2aee11df4e94f29b51677bd827
https://pubmed.ncbi.nlm.nih.gov/34776417
https://pubmed.ncbi.nlm.nih.gov/34776417
Autor:
Stephen J. Kolb, Kelly A. Rich, Vibhor Krishna, Raphael A. Malbrue, Elizabeth Keckley, Megan G. Pino, Lori Mattox, Ranjit Ganguly, Brad Youngblood, Ashley Fox, Matthew Joseph
Publikováno v:
Journal of Neuroscience Methods. 366:109403
Background Longitudinal access to cerebrospinal fluid (CSF) is useful for biomarker discovery in neurological disorders or diseases affecting CSF composition. Here, we aim to test a new method for insertion of a permanent intrathecal catheter, facili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6525cfd41d1b4422b84f965e8baf41
https://doi.org/10.1016/j.jneumeth.2021.109403
https://doi.org/10.1016/j.jneumeth.2021.109403
Autor:
Sumanas W. Jordan, Steven A Schulz, Megan G. Pino, Amy Drake, Casey T. Kraft, Trevor Hodson, Roman J. Skoracki, Jason D. Hehr, Albert H. Chao
Publikováno v:
Microsurgery. 39:282-283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39795cc1e855184561646a030bdb5882
https://doi.org/10.1002/micr.30415
https://doi.org/10.1002/micr.30415
Autor:
Patricia Belle, E. Christopher Ellison, Robert E. Merritt, David S. Strosberg, Anahita Jalilvand, Megan G. Pino, Michelle C. Nguyen, Kyle A. Perry
Publikováno v:
Journal of the American College of Surgeons. 227:S21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5562fc2125ad53f2edea39bdabb8c6e6
https://doi.org/10.1016/j.jamcollsurg.2018.07.024
https://doi.org/10.1016/j.jamcollsurg.2018.07.024