Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Megan Finch-Edmondson"'
Autor:
Madeleine J. Smith, Megan Finch-Edmondson, Suzanne L. Miller, Annabel Webb, Michael C. Fahey, Graham Jenkin, Madison Claire Badawy Paton, Courtney A. McDonald
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background Neural stem cells (NSCs) have the potential to engraft and replace damaged brain tissue, repairing the damaged neonatal brain that causes cerebral palsy (CP). There are procedures that could increase engraftment of NSCs and may be
Externí odkaz:
https://doaj.org/article/8f98cff0d84f43dfabe0f303cf62d28e
Autor:
Madeleine J. Smith, Tayla Penny, Yen Pham, Amy E. Sutherland, Graham Jenkin, Michael C. Fahey, Madison C. B. Paton, Megan Finch-Edmondson, Suzanne L. Miller, Courtney A. McDonald
Publikováno v:
Cells, Vol 12, Iss 22, p 2659 (2023)
(1) Background: Neonatal brain injury can lead to permanent neurodevelopmental impairments. Notably, suppressing inflammatory pathways may reduce damage. To determine the role of neuroinflammation in the progression of neonatal brain injury, we inves
Externí odkaz:
https://doaj.org/article/3d4c13f9aded4afa9e7aaa537e5ae941
Autor:
Madeleine J. Smith, Madison Claire Badawy Paton, Michael C. Fahey, Graham Jenkin, Suzanne L. Miller, Megan Finch‐Edmondson, Courtney A. McDonald
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1621-1636 (2021)
Abstract Perinatal brain injury can lead to significant neurological and cognitive deficits and currently no therapies can regenerate the damaged brain. Neural stem cells (NSCs) have the potential to engraft and regenerate damaged brain tissue. The a
Externí odkaz:
https://doaj.org/article/0061f57653f24b59ac6f72966506fbc0
Autor:
Bowen Zhu, Megan Finch-Edmondson, Kim Whye Leong, Xiaoqian Zhang, Mitheera V., Quy Xiao Xuan Lin, Yaelim Lee, Wei Ting Ng, Huili Guo, Yue Wan, Marius Sudol, Ramanuj DasGupta
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Long non-coding RNAs (lncRNAs) regulate numerous biological processes involved in both development and carcinogenesis. Hippo-YAP/TAZ signaling, a critical pathway responsible for organ size control, is often dysregulated in a variety of canc
Externí odkaz:
https://doaj.org/article/4991791ee8144a329868ce14d5a6273d
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/69abd7a194984501b32ac43962389fb2
Autor:
Megan Finch-Edmondson, Madison C. B. Paton, Ingrid Honan, Petra Karlsson, Candice Stephenson, Darryl Chiu, Sarah Reedman, Alexandra R. Griffin, Catherine Morgan, Iona Novak
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 24, p 7319 (2022)
Cell therapies are an emergent treatment for cerebral palsy (CP) with promising evidence demonstrating efficacy for improving gross motor function. However, families value improvements in a range of domains following intervention and the non-motor sy
Externí odkaz:
https://doaj.org/article/03ea0c6cab234ea8a7603d037ac7e31c
Autor:
Madison C. B. Paton, Megan Finch-Edmondson, Russell C. Dale, Michael C. Fahey, Claudia A. Nold-Petry, Marcel F. Nold, Alexandra R. Griffin, Iona Novak
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 24, p 7368 (2022)
Research has established inflammation in the pathogenesis of brain injury and the risk of developing cerebral palsy (CP). However, it is unclear if inflammation is solely pathogenic and primarily contributes to the acute phase of injury, or if inflam
Externí odkaz:
https://doaj.org/article/243fcfebdab54c60b24d3af2a17d8e2c
Autor:
Iona Novak, Anna te Velde, Ashleigh Hines, Emma Stanton, Maria Mc Namara, Madison C. B. Paton, Megan Finch-Edmondson, Catherine Morgan
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 2 (2021)
Evidence-based practice is the foundation of rehabilitation for maximizing client outcomes. However, an unacceptably high number of ineffective or outdated interventions are still implemented, leading to sub-optimal outcomes for clients. This paper p
Externí odkaz:
https://doaj.org/article/4c627fcadd58472ca09b1b876b016045
Autor:
Adam M. Passman, Robyn P. Strauss, Sarah B. McSpadden, Megan Finch-Edmondson, Neil Andrewartha, Ken H. Woo, Luke A. Diepeveen, Weihao Zhao, Joaquín Fernández-Irigoyen, Enrique Santamaría, Laura Medina-Ruiz, Martyna Szpakowska, Andy Chevigné, Hyerin Park, Rodrigo Carlessi, Janina E. E. Tirnitz-Parker, José R. Blanco, Roslyn London, Bernard A. Callus, Caryn L. Elsegood, Murray V. Baker, Alfredo Martínez, George C. T. Yeoh, Laura Ochoa-Callejero
Publikováno v:
Cancers, Vol 13, Iss 19, p 4935 (2021)
Maraviroc (MVC), a CCR5 antagonist, reduces liver fibrosis, injury and tumour burden in mice fed a hepatocarcinogenic diet, suggesting it has potential as a cancer therapeutic. We investigated the effect of MVC on liver progenitor cells (LPCs) and ma
Externí odkaz:
https://doaj.org/article/000e95e0395c41b2bc6bf4a15f905498
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Worldwide, an estimated 15 million babies are born preterm (
Externí odkaz:
https://doaj.org/article/24b06237a09149a1bcb61b28c2e67b35