Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Megan E. Spurgeon"'
Autor:
Megan E. Spurgeon, Elizabeth C. Townsend, Simon Blaine-Sauer, Stephanie M. McGregor, Mark Horswill, Johan A. den Boon, Paul Ahlquist, Lindsay Kalan, Paul F. Lambert
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Human papillomaviruses (HPVs) are the most common sexually transmitted infection in the United States and are a major etiological agent of cancers in the anogenital tract and oral cavity. Growing evidence suggests changes in the host microbi
Externí odkaz:
https://doaj.org/article/18ee43ed5a314b4e8e898804dce9b0d2
Autor:
Megan E. Spurgeon
Publikováno v:
Tumour Virus Research, Vol 14, Iss , Pp 200239- (2022)
Human tumor viruses cause various human cancers that account for at least 15% of the global cancer burden. Among the currently identified human tumor viruses, two are small DNA tumor viruses: human papillomaviruses (HPVs) and Merkel cell polyomavirus
Externí odkaz:
https://doaj.org/article/5061dbb8f69341b9b16a09659760b635
Publikováno v:
Viruses, Vol 14, Iss 10, p 2204 (2022)
Merkel cell polyomavirus (MCPyV) is the only human polyomavirus currently known to cause human cancer. MCPyV is believed to be an etiological factor in at least 80% of cases of the rare but aggressive skin malignancy Merkel cell carcinoma (MCC). In t
Externí odkaz:
https://doaj.org/article/bebb9ead2c1c4f1f9f34ba432556ce91
Autor:
Megan E. Spurgeon
Publikováno v:
mSphere, Vol 4, Iss 4 (2019)
ABSTRACT Megan E. Spurgeon works in the field of viral oncology. In this mSphere of Influence article, she reflects on how the paper “Rescuing US biomedical research from its systemic flaws” by Bruce Alberts, Marc W. Kirschner, Shirley Tilghman,
Externí odkaz:
https://doaj.org/article/0e5f7def776642ac9b6354d0849fc185
Autor:
Megan E. Spurgeon, Aayushi Uberoi, Stephanie M. McGregor, Tao Wei, Ella Ward-Shaw, Paul F. Lambert
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Papillomaviruses exhibit species-specific tropism, thereby limiting understanding and research of several aspects of HPV infection and carcinogenesis. The discovery of a murine papillomavirus (MmuPV1) provides the opportunity to study papill
Externí odkaz:
https://doaj.org/article/1c489332ada44e738485519c743d7fc2
Publikováno v:
Viruses, Vol 13, Iss 1, p 138 (2021)
Merkel cell polyomavirus (MCPyV) is a human polyomavirus causally linked to the development of Merkel cell carcinoma (MCC), an aggressive malignancy that largely arises within the dermis of the skin. In this study, we recapitulate the histopathology
Externí odkaz:
https://doaj.org/article/e4feb725d9bc4068be28c48992c16156
Autor:
Megan E. Spurgeon, Paul F. Lambert
Publikováno v:
Viruses, Vol 9, Iss 8, p 219 (2017)
Human papillomaviruses (HPVs) are double-stranded DNA (dsDNA) tumor viruses that are causally associated with human cancers of the anogenital tract, skin, and oral cavity. Despite the availability of prophylactic vaccines, HPVs remain a major global
Externí odkaz:
https://doaj.org/article/5121279ec01b458a870baa6515bed3a3
Autor:
Megan E Spurgeon, Jingwei Cheng, Ella Ward-Shaw, Frederick A Dick, James A DeCaprio, Paul F Lambert
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010551 (2022)
Clear evidence supports a causal link between Merkel cell polyomavirus (MCPyV) and the highly aggressive human skin cancer called Merkel cell carcinoma (MCC). Integration of viral DNA into the human genome facilitates continued expression of the MCPy
Externí odkaz:
https://doaj.org/article/20d6ff3165f54718b5c7480b0f8a536c
Autor:
Megan E Spurgeon, Paul F Lambert
Publikováno v:
eLife, Vol 8 (2019)
Human papillomaviruses (HPVs) are the most common sexually transmitted infectious agents. Because of the species specificity of HPVs, study of their natural transmission in laboratory animals is not possible. The papillomavirus, MmuPV1, which infects
Externí odkaz:
https://doaj.org/article/1fd8f0d320754eb1bdd9169b29e72ef1
Supplementary Figure Legends. Legends for Supplementary Figures S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e71797fe0fd799cfbcbe2b5faa776751
https://doi.org/10.1158/0008-5472.22406828.v1
https://doi.org/10.1158/0008-5472.22406828.v1
