Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Megan E. Schroeder"'
Autor:
Megan E. Schroeder, Dilara Batan, Andrea Gonzalez Rodriguez, Kelly F. Speckl, Douglas K. Peters, Bruce E. Kirkpatrick, Grace K. Hach, Cierra J. Walker, Joseph C. Grim, Brian A. Aguado, Robert M. Weiss, Kristi S. Anseth
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Patients with aortic valve stenosis (AVS) have sexually dimorphic phenotypes in their valve tissue, where male valvular tissue adopts a calcified phenotype and female tissue becomes more fibrotic. The molecular mechanisms that regulate sex
Externí odkaz:
https://doaj.org/article/4f693d1bbced4f58a85c14afab8db778
Autor:
Cierra J. Walker, Dilara Batan, Carrie T. Bishop, Daniel Ramirez, Brian A. Aguado, Megan E. Schroeder, Claudia Crocini, Jessica Schwisow, Karen Moulton, Laura Macdougall, Robert M. Weiss, Mary A. Allen, Robin Dowell, Leslie A. Leinwand, Kristi S. Anseth
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Aortic valve stenosis (AVS) is a progressive fibrotic disease that is caused by thickening and stiffening of valve leaflets. At the cellular level, quiescent valve interstitial cells (qVICs) activate to myofibroblasts (aVICs) that persist wi
Externí odkaz:
https://doaj.org/article/7131e16927834fb5a636e98358625fa7
Publikováno v:
APL Bioengineering, Vol 2, Iss 4, Pp 046104-046104-13 (2018)
Valvular interstitial cells (VICs) are responsible for the maintenance of the extracellular matrix in heart valve leaflets and, in response to injury, activate from a quiescent fibroblast to a wound healing myofibroblast phenotype. Under normal condi
Externí odkaz:
https://doaj.org/article/bee6836cef0d4786b6656ed8ae37b2ad
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 35:178-181
Trichomonosis is a venereal disease of cattle caused by the protozoan Tritrichomonas foetus. T. foetus infection in cattle herds can be economically costly for cattle producers; therefore, testing is important for detection of the agent. Given that b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efb78297a2a7df69ceeb93f788d315f
https://doi.org/10.1177/10406387221149407
https://doi.org/10.1177/10406387221149407
Autor:
Brian A. Aguado, Cierra J. Walker, Joseph C. Grim, Megan E. Schroeder, Dilara Batan, Brandon J. Vogt, Andrea Gonzalez Rodriguez, Jessica A. Schwisow, Karen S. Moulton, Robert M. Weiss, Donald D. Heistad, Leslie A. Leinwand, Kristi S. Anseth
Publikováno v:
Circulation
Background: Aortic valve stenosis is a sexually dimorphic disease, with women often presenting with sustained fibrosis and men with more extensive calcification. However, the intracellular molecular mechanisms that drive these clinically important se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4b1a231933a2a681874ebcb7018338
https://doi.org/10.1161/circulationaha.121.054108
https://doi.org/10.1161/circulationaha.121.054108
Publikováno v:
J Mol Cell Cardiol
Nearly all cardiovascular diseases show sexual dimorphisms in prevalence, presentation, and outcomes. Until recently, most clinical trials were carried out in males, and many animal studies either failed to identify the sex of the animals or combined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a7ee1c7ebd6f6baae2ee7af357c1a9
https://doi.org/10.1016/j.yjmcc.2021.04.010
https://doi.org/10.1016/j.yjmcc.2021.04.010
Autor:
Megan E. Schroeder, Dilara Batan, Andrea Gonzalez Rodriguez, Kelly F. Speckl, Douglas K. Peters, Bruce E. Kirkpatrick, Grace K. Hach, Cierra J. Walker, Joseph C. Grim, Brian A. Aguado, Robert M. Weiss, Kristi S. Anseth
Publikováno v:
Bioengineering & Translational Medicine. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::712428853d3f88edc8bacaf69ba2bb9e
https://doi.org/10.1002/btm2.10358
https://doi.org/10.1002/btm2.10358
Autor:
Robert M. Weiss, Joseph C. Grim, Kelly F. Speckl, Kristi S. Anseth, Cierra J. Walker, Firaol S. Midekssa, Megan E. Schroeder, Andrea Gonzalez Rodriguez
Publikováno v:
Acta Biomater
Enzymatically degradable hydrogels were designed for the 3D culture of valvular interstitial cells (VICs), and through the incorporation of various functionalities, we aimed to investigate the role of the tissue microenvironment in promoting the oste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c924687744cc8223bb1d276d223ddf34
https://doi.org/10.1016/j.actbio.2020.11.012
https://doi.org/10.1016/j.actbio.2020.11.012
Autor:
null Megan E. Schroeder, null Dilara Batan, null Andrea Gonzalez Rodriguez, null Kelly F. Speckl, null Douglas K. Peters, null Bruce E. Kirkpatrick, null Grace K. Hach, null Cierra J. Walker, null Joseph C. Grim, null Brian A. Aguado, null Robert M. Weiss, null Kristi S. Anseth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8328e69e0c5fabc4af47011f829d3f5b
https://doi.org/10.1002/btm2.10358/v3/response1
https://doi.org/10.1002/btm2.10358/v3/response1
Autor:
Dilara Batan, Douglas K. Peters, Megan E. Schroeder, Brian A. Aguado, Mark W. Young, Robert M. Weiss, Kristi S. Anseth
Publikováno v:
FASEB J
As aortic valve stenosis develops, valve tissue becomes stiffer. In response to this change in environmental mechanical stiffness, valvular interstitial cells (VICs) activate into myofibroblasts. We aimed to investigate the role of mechanosensitive c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8232c12854d0cb4e5d9e4e48482486
https://pubmed.ncbi.nlm.nih.gov/35385164
https://pubmed.ncbi.nlm.nih.gov/35385164