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of 5
pro vyhledávání: '"Megan E. Pask"'
Autor:
Christia M. Victoriano, Megan E. Pask, Nicole A. Malofsky, Adam Seegmiller, Steve Simmons, Jonathan E. Schmitz, Frederick R. Haselton, Nicholas M. Adams
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract PCR-based diagnostics generally require nucleic acid extraction from patient specimens prior to amplification. As highlighted early in the COVID-19 pandemic, extraction steps may be difficult to scale during times of massive demand and limit
Externí odkaz:
https://doaj.org/article/de69f5555a644c808ef462f0d7e32cc4
Magnetic Bead Processing Enables Sensitive Ligation-Based Detection of HIV Drug Resistance Mutations
Autor:
Dalton J. Nelson, Mindy Leelawong, Megan E. Pask, C. William Wester, Muktar H. Aliyu, Frederick R. Haselton
Publikováno v:
Analytical chemistry. 94(5)
HIV develops single nucleotide polymorphisms (SNPs), some of which lead to drug resistance mutations (DRMs) that prevent therapeutic viral suppression. Genomic sequencing enables healthcare professionals to select effective combination antiretroviral
Autor:
Anna E. Wolfe, Nicholas M. Adams, Patricia K. Russ, Cassandra Wessely, Megan E. Pask, Mindy Leelawong, Kelly A. Richardson, Frederick R. Haselton, Stephanie I. Pearlman
Publikováno v:
ACS Applied Materials & Interfaces
Nucleic acid-based diagnostic tests often require isolation and concentration of nucleic acids from biological samples. Commercial purification kits are difficult to use in low-resource settings because of their cost and insufficient laboratory infra
Autor:
April C. Pettit, Andrew J.M. Nel, David W. Wright, Carlos Zamudio, Frederick R. Haselton, Mark L. Baglia, Megan E. Pask, Keersten M. Ricks, Keertan Dheda, Hali Bordelon, Francesca Solinas, Patricia K. Russ, Tatiana Cáceres, Philip A. Short, Jonathan Michael Blackburn
Urine samples are increasingly used for diagnosing infections including Escherichia coli, Ebola virus, and Zika virus. However, extraction and concentration of nucleic acid biomarkers from urine is necessary for many molecular detection strategies su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7c930098e0834861b260dcd4529acd
https://hdl.handle.net/20.500.12866/4631
https://hdl.handle.net/20.500.12866/4631
Autor:
Holly Cassell, Philip J. Ciampa, José A. Tique, Megan E. Pask, Carolyn M. Audet, Sten H. Vermund
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 63:S12-S25
Early achievements in biomedical approaches for HIV prevention included physical barriers (condoms), clean injection equipment (both for medical use and for injection drug users), blood and blood product safety, and prevention of mother to child tran