Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Megan E. McCarron"'
Deep learning-based analysis of macaque corneal sub-basal nerve fibers in confocal microscopy images
Autor:
Jonathan D. Oakley, Daniel B. Russakoff, Megan E. McCarron, Rachel L. Weinberg, Jessica M. Izzi, Stuti L. Misra, Charles N. McGhee, Joseph L. Mankowski
Publikováno v:
Eye and Vision, Vol 7, Iss 1, Pp 1-11 (2020)
Abstract Background To develop and validate a deep learning-based approach to the fully-automated analysis of macaque corneal sub-basal nerves using in vivo confocal microscopy (IVCM). Methods IVCM was used to collect 108 images from 35 macaques. 58
Externí odkaz:
https://doaj.org/article/3720f057249746ea88f4472647bdcbfd
Autor:
Suzanne E. Queen, Daniel B. Russakoff, Stuti L. Misra, Jessica M. Izzi, Rachel L. Weinberg, Jonathan D. Oakley, Megan E. McCarron, Joseph L. Mankowski, Patrick M. Tarwater
Publikováno v:
Cornea
Purpose To characterize corneal subbasal nerve plexus features of normal and simian immunodeficiency virus (SIV)-infected macaques by combining in vivo corneal confocal microscopy (IVCM) with automated assessments using deep learning-based methods cu
Autor:
Audrey C Knight, Suzanne E. Queen, Joseph L. Mankowski, Clarisse V. Solis, Morgan R. Richardson, Charles C. Bailey, Megan E. McCarron, Samuel A. Brill
Publikováno v:
J Neurovirol
HIV-associated neuroinflammation is primarily driven by CNS macrophages including microglia. Regulation of these immune responses, however, remains to be characterized in detail. Using the SIV/macaque model of HIV, we evaluated CNS expression of trig
Autor:
Santosh Dhakal, Andrew Pekosz, Sabra L. Klein, Morgan R. Richardson, Petros C. Karakousis, Alicia M Braxton, Paula Marinho, Selena Guerrero-Martin, Andrew L. Johanson, Sanjay K. Jain, Jacqueline Brockhurst, Joseph L. Mankowski, Patrick M. Tarwater, Erin N. Shirk, Kathleen R. Mulka, Megan E. McCarron, Ruifeng Zhou, Clarisse V. Solis, Kelly A. Metcalf Pate, Sarah E. Beck, Jason S Villano, Suzanne E. Queen, Rebecca T. Veenhuis, Anne E. Jedlicka, Patrick S. Creisher, Cory Brayton
To catalyze SARS-CoV-2 research including development of novel interventive and preventive strategies, we characterized progression of disease in depth in a robust COVID-19 animal model. In this model, male and female golden Syrian hamsters were inoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8f50d4c9d3d0beb92fd97864c54f3c3
https://doi.org/10.1101/2021.06.25.449918
https://doi.org/10.1101/2021.06.25.449918
Autor:
Kathleen R. Mulka, Sarah E. Beck, Clarisse V. Solis, Andrew L. Johanson, Suzanne E. Queen, Megan E. McCarron, Morgan R. Richardson, Ruifeng Zhou, Paula Marinho, Anne Jedlicka, Selena Guerrero-Martin, Erin N. Shirk, Alicia M. Braxton, Jacqueline Brockhurst, Patrick S. Creisher, Santosh Dhakal, Cory F. Brayton, Rebecca T. Veenhuis, Kelly A. Metcalf Pate, Petros C. Karakousis, Cynthia A. Zahnow, Sabra L. Klein, Sanjay K. Jain, Patrick M. Tarwater, Andrew S. Pekosz, Jason S. Villano, Joseph L. Mankowski, Michael J. Betenbaugh, Bess Carlson, Natalie Castell, Jennie Ruelas Castillo, Kelly Flavahan, Eric K. Hutchinson, Kirsten Littlefield, Monika M. Looney, Maggie Lowman, Natalia Majewski, Amanda Maxwell, Filipa Mota, Alice L. Mueller, Alvaro A. Ordonez, Lisa Pieterse, Darla Quijada, Camilo A. Ruiz-Bedoya, Mitchel Stover, Rachel Vistein, Melissa Wood
Publikováno v:
The American Journal of Pathology
To catalyze severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) research, including development of novel interventive and preventive strategies, the progression of disease was characterized in a robust coronavirus disease 2019 (COVID-19) ani
Autor:
Daniel B. Russakoff, Suzanne E. Queen, Jonathan D. Oakley, Joseph L. Mankowski, Stuti L. Misra, Jessica M. Izzi, Rachel L. Weinberg, Megan E. McCarron
PurposeTo characterize corneal subbasal nerve plexus morphologic features using in vivo corneal confocal microscopy (IVCM) in normal and SIV-infected macaques and to implement automated assessments using novel deep learning-based methods customized f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcc1e447db7b82090f9648dee9ce296
Deep Learning-Based Analysis of Macaque Corneal Sub-Basal Nerve Fibers in Confocal Microscopy Images
Autor:
Daniel B. Russakoff, Joseph L. Mankowski, Megan E. McCarron, Jessica M. Izzi, Jonathan D. Oakley, Rachel L. Weinberg
PurposeTo describe and assess different deep learning-based methods for automated measurement of macaque corneal sub-basal nerves using in vivo confocal microscopy (IVCM).MethodsThe automated assessment of corneal nerve fiber length (CNFL) in IVCM im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e9b0dfc0bae3c87b53298569e8c4f4
Autor:
Carl F. Marfurt, Miracle C. Anokwute, Kaleigh Fetcko, Rachel L. Weinberg, Megan E. McCarron, Joseph L. Mankowski, Erin Mahony-Perez, Hassan Farooq, Maraya M. Baumanis, Emily Ross
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The subbasal nerve plexus (SNP) is the densest and most recognizable component of the mammalian corneal innervation; however, the anatomical configuration of the SNP in most animal models remains incompletely described. The purpose of the cur