Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Megan E. Jewett"'
Autor:
Elizabeth B. Klerman, Dennis A. Dean, Richard E. Kronauer, Emery N. Brown, Premananda Indic, Daniel B. Forger, Megan E. Jewett, Melissa A. St. Hilaire
Publikováno v:
Chronobiology International. 22:613-629
At an organism level, the mammalian circadian pacemaker is a two-dimensional system. For these two dimensions, phase (relative timing) and amplitude of the circadian pacemaker are commonly used. Both the phase and the amplitude (A) of the human circa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f2433e4257b7870eb46ca6afaa1694
https://doi.org/10.1080/07420520500180371
https://doi.org/10.1080/07420520500180371
Publikováno v:
Journal of Pineal Research. 35:149-157
The human circadian pacemaker, with an intrinsic period between 23.9 and 24.5 hr, can be reset by low levels of light. Biomathematical models of the human clock predict that light-dark cycles consisting of only approximately 3.5 lux during 16 hr of w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9bb8577c5235d39ca5699e583d18652
https://doi.org/10.1034/j.1600-079x.2003.00072.x
https://doi.org/10.1034/j.1600-079x.2003.00072.x
Publikováno v:
Journal of Biological Rhythms. 14:500-515
The authors' previous models have been able to describe accurately the effects of extended (approximately 5 h) bright-light (>4000 lux) stimuli on the phase and amplitude of the human circadian pacemaker, but they are not sufficient to represent the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f51a7dc06ac3f1758f3d8b387325f4
https://doi.org/10.1177/074873099129001073
https://doi.org/10.1177/074873099129001073
Publikováno v:
Journal of Biological Rhythms. 14:493-500
In 1990, Kronauer proposed a mathematical model of the effects of light on the human circadian pacemaker. This study presents several refinements to Kronauer's original model of the pacemaker that enable it to predict more accurately the experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b737d7166c41213a8f075256b994911d
https://doi.org/10.1177/074873049901400608
https://doi.org/10.1177/074873049901400608
Publikováno v:
Journal of Biological Rhythms. 14:533-538
Numerous studies have used the classic van der Pol oscillator, which contains a cubic nonlinearity, to model the effect of light on the human circadian pacemaker. Jewett and Kronauer demonstrated that Aschoff's rule could be incorporated into van der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::390bbdb51a9741877fe9660c1ebfb33d
https://doi.org/10.1177/074873099129000867
https://doi.org/10.1177/074873099129000867
Autor:
Richard E. Kronauer, Megan E. Jewett
Publikováno v:
Journal of Biological Rhythms. 14:588-597
The authors present here mathematical models in which levels of subjective alertness and cognitive throughput are predicted by three components that interact with one another in a nonlinear manner. These components are (1) a homeostatic component ( H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e900cec72270c23e6b5fd09f43c621
https://doi.org/10.1177/074873099129000920
https://doi.org/10.1177/074873099129000920
Autor:
Megan E. Jewett, Richard E. Kronauer
Publikováno v:
Journal of Theoretical Biology. 192:455-465
In 1990, Kronauer proposed a mathematical model of the effects of light on the human circadian pacemaker. Although this model predicted many general features of the response of the human circadian pacemaker to light exposure, additional data now avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894ca1d2e10a20f3c4b541d4b685b206
https://doi.org/10.1006/jtbi.1998.0667
https://doi.org/10.1006/jtbi.1998.0667
Autor:
Megan E. Jewett, Elizabeth B. Klerman, Jeanne F. Duffy, Charles A. Czeisler, D. W. Rimmer, Richard E. Kronauer
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 273:R1800-R1809
Fifty-six resetting trials were conducted across the subjective day in 43 young men using a three-cycle bright-light (∼10,000 lx) stimulus against a background of very dim light (10–15 lx). The phase-response curve (PRC) to these trials was asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60865655af29d3d867683ede93ca4d9
https://doi.org/10.1152/ajpregu.1997.273.5.r1800
https://doi.org/10.1152/ajpregu.1997.273.5.r1800
Publikováno v:
Journal of Biological Rhythms. 9:295-314
We present here an analysis of strong, weak, and critical bright-light resetting trials in humans, and report not only phase but also amplitude data for the first time. For this analysis, an appropriate iterative smoothing procedure for phase transit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfc81321b71c39b0083fdcb97c600f9
https://doi.org/10.1177/074873049400900310
https://doi.org/10.1177/074873049400900310
Publikováno v:
Journal of Biological Rhythms. 8:351-360
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acb358206e6af8da1406103fb3fee882
https://doi.org/10.1177/074873049300800409
https://doi.org/10.1177/074873049300800409