Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Megan E. Gumina"'
Autor:
Sigrid Gouma, Kangchon Kim, Madison E. Weirick, Megan E. Gumina, Angela Branche, David J. Topham, Emily T. Martin, Arnold S. Monto, Sarah Cobey, Scott E. Hensley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Influenza exposure in early childhood can affect the immune response to distinct viral strains later in life. Here, Gouma et al. show that contemporary 3c2.A H3N2 virus infections boost non-neutralizing H3N2 antibodies in middle-aged individuals, pot
Externí odkaz:
https://doaj.org/article/792227af26bb4898b50fc41e24abb5db
Autor:
Seth J. Zost, Juhye Lee, Megan E. Gumina, Kaela Parkhouse, Carole Henry, Nicholas C. Wu, Chang-Chun D. Lee, Ian A. Wilson, Patrick C. Wilson, Jesse D. Bloom, Scott E. Hensley
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4460-4470.e8 (2019)
Summary: Antibodies targeting the receptor binding site (RBS) of the influenza virus hemagglutinin (HA) protein are usually not broadly reactive because their footprints are typically large and extend to nearby variable HA residues. Here, we identify
Externí odkaz:
https://doaj.org/article/e5ef4f195b5a4b32bd4bcefba23a1917
Autor:
Chang-Chun D Lee, Carole Henry, Juhye M. Lee, Seth J. Zost, Nicholas C. Wu, Ian A. Wilson, Kaela Parkhouse, Megan E. Gumina, Jesse D. Bloom, Scott E. Hensley, Patrick C. Wilson
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4460-4470.e8 (2019)
Cell reports
Cell reports
SUMMARY Antibodies targeting the receptor binding site (RBS) of the influenza virus hemagglutinin (HA) protein are usually not broadly reactive because their footprints are typically large and extend to nearby variable HA residues. Here, we identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f336325eee91285092bcd0ab49baaea
http://www.sciencedirect.com/science/article/pii/S221112471931575X
http://www.sciencedirect.com/science/article/pii/S221112471931575X
Autor:
Megan E. Gumina, Albert C. Yan
Publikováno v:
Pediatric Dermatology. 38:329-331
A 13-year-old female patient presented with a 3-month history of recurrent blisters, which ruptured into multiple superficial erosions with overlying crust located on the face, neck, and shoulder. Treatment for presumed bullous impetigo showed no ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92c7d3ad387fc78533e53a1e5c2d09b
https://doi.org/10.1111/pde.14453
https://doi.org/10.1111/pde.14453
Autor:
Arnold S. Monto, Megan E. Gumina, Kangchon Kim, Sarah Cobey, Angela Branche, David J. Topham, Emily T. Martin, Sigrid Gouma, Scott E. Hensley, Madison E. Weirick
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Influenza virus exposures in childhood can establish long-lived memory B cell responses that can be recalled later in life. Here, we complete a large serological survey to elucidate the specificity of antibodies against contemporary H3N2 viruses in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e55f1460f76dd9813bd5b139217259
http://europepmc.org/articles/PMC7486384
http://europepmc.org/articles/PMC7486384
Autor:
James D. Phelan, Mina O. Seedhom, Rigel J. Kishton, Tovah E. Markowitz, Nicholas P. Restifo, Justin B. Lack, Jonathan W. Yewdell, Craig J. Thomas, George E. Wright, Jesse H. Arbuckle, Thomas M. Kristie, Boya Wang, Da-Wei Huang, Devin Dersh, Jaroslav Holly, Megan E. Gumina, Michele Ceribelli, Louis M. Staudt, Nathan Fridlyand
SummaryTumors frequently subvert MHC class I (MHC-I) peptide presentation to evade CD8+ T cell immunosurveillance. To better define the regulatory networks controlling antigen presentation, we employed genome-wide screening in human diffuse large B c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d770b191f5ac73f8604b65ee902b7d31
https://doi.org/10.1101/2020.03.13.989558
https://doi.org/10.1101/2020.03.13.989558
Autor:
Scott E. Hensley, Patrick C. Wilson, Seth J. Zost, Sarah Cobey, Andrea J. Sant, Megan E. Gumina, John J. Treanor, Sebastian Diaz Perez, Kaela Parkhouse, Kangchon Kim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The majority of influenza vaccine antigens are prepared in chicken eggs. Human vaccine strains grown in eggs often possess adaptive mutations that increase viral attachment to chicken cells. Most of these adaptive mutations are in the he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622fcaddcada5cd102357304f5918366
https://doi.org/10.1073/pnas.1712377114
https://doi.org/10.1073/pnas.1712377114
Autor:
Juhye M. Lee, Carole Henry, Kaela Parkhouse, Patrick C. Wilson, Seth J. Zost, Scott E. Hensley, Jesse D. Bloom, Megan E. Gumina
SUMMARYAntibodies targeting the receptor binding site (RBS) of the influenza virus hemagglutinin (HA) protein are usually not broadly-reactive because their footprints are typically large and extend to nearby variable HA residues. Here, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db284ff699c911dae585b8e4a2653373
Autor:
Albert C. Yan, Megan E. Gumina
Publikováno v:
Pediatric dermatology. 36(4)
Infantile hemangiomas are the most common tumors of infancy and are often managed with oral beta-blockers to address or prevent associated complications. However, treatment with propranolol can occasionally be associated with sleep disturbances, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9e93f709e2313b9e065c6aa2f8f0d5
https://pubmed.ncbi.nlm.nih.gov/30983047
https://pubmed.ncbi.nlm.nih.gov/30983047
Autor:
Tovah E. Markowitz, Louis M. Staudt, Jonathan W. Yewdell, Boya Wang, Craig J. Thomas, George E. Wright, Justin B. Lack, Nathan Fridlyand, Nicholas P. Restifo, Da-Wei Huang, James D. Phelan, Mina O. Seedhom, Megan E. Gumina, Thomas M. Kristie, Rigel J. Kishton, Devin Dersh, Jaroslav Holly, Jesse H. Arbuckle, Michele Ceribelli
Publikováno v:
Immunity
Summary Tumors frequently subvert major histocompatibility complex class I (MHC-I) peptide presentation to evade CD8+ T cell immunosurveillance, though how this is accomplished is not always well defined. To identify the global regulatory networks co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff369fa599bc0a66fe9431a3e86e85e
https://doi.org/10.1016/j.immuni.2020.11.002
https://doi.org/10.1016/j.immuni.2020.11.002