Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Megan E. Ermler"'
Autor:
Irene Ramos, Mena Mansour, Teddy J. Wohlbold, Megan E. Ermler, Ariana Hirsh, Jonathan A. Runstadler, Ana Fernandez-Sesma, Florian Krammer
Publikováno v:
Emerging Infectious Diseases, Vol 21, Iss 7, Pp 1197-1201 (2015)
Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly wit
Externí odkaz:
https://doaj.org/article/9898040e97854874bbd4eb27ef05e515
Autor:
Madhusudan Rajendran, Raffael Nachbagauer, Megan E. Ermler, Paul Bunduc, Fatima Amanat, Ruvim Izikson, Manon Cox, Peter Palese, Maryna Eichelberger, Florian Krammer
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT Antibody responses to influenza virus hemagglutinin provide protection against infection and are well studied. Less is known about the human antibody responses to the second surface glycoprotein, neuraminidase. Here, we assessed human antibo
Externí odkaz:
https://doaj.org/article/7c9329d833a84c95bbc4fca196652c5c
Autor:
Victor H. Leyva-Grado, Megan E. Ermler, Michael Schotsaert, Ma G. Gonzalez, Virginia Gillespie, Jean K. Lim, Adolfo García-Sastre
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT An exacerbated immune response is one of the main causes of influenza-induced lung damage during infection. The molecular mechanisms regulating the fate of the initial immune response to infection, either as a protective response or as detri
Externí odkaz:
https://doaj.org/article/4218a4b7f976483582ade0a67e8e217f
Autor:
Pamela T. Wong, Megan E. Ermler, Jessica J. O’Konek, Rachel Sun, Peter H. Goff, Jeffrey J. Landers, Matthew J. Ruge, Alyssa Sebring, Katarzyna W. Janczak, Weina Sun, James R. Baker
Publikováno v:
Molecular Pharmaceutics. 18:679-698
Current influenza virus vaccines are focused on humoral immunity and are limited by the short duration of protection, narrow cross-strain efficacy, and suboptimal immunogenicity. Here, we combined two chemically and biologically distinct adjuvants, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56a6312ebbe4cb8428a6ecee2e15fb0
https://doi.org/10.1021/acs.molpharmaceut.0c00315
https://doi.org/10.1021/acs.molpharmaceut.0c00315
Autor:
Peter Palese, Anna-Karin E. Palm, Patrick C. Wilson, Marie Van der Wielen, Rahnuma Wahid, Michelle Dickey, Jeffrey T. Guptill, Rong Hai, Chris Gast, Haley L. Dugan, David I. Bernstein, Alicia Solórzano, Abdollah Naficy, Christopher T. Stamper, Monica M. McNeal, Raffael Nachbagauer, Min Gao, Emmanuel B. Walter, Linda Yu-Ling Lan, Randy A. Albrecht, Dustin G. Shaw, Florian Krammer, Micah E. Tepora, Jodi Feser, Heather Wenzel, Megan E Ermler, Jenna J. Guthmiller, D. Freeman, Bruce L Innis, Adolfo García-Sastre, Carine Claeys, Kristen N Buschle, Weina Sun, Teddy John Wohlbold, Carole Henry, Victoria Sutton, Francesco Berlanda-Scorza, Yao-Qing Chen
Publikováno v:
The Lancet. Infectious Diseases
The Lancet. Infectious diseases, vol 20, iss 1
The Lancet. Infectious diseases, vol 20, iss 1
Summary Background Influenza viruses cause substantial annual morbidity and mortality globally. Current vaccines protect against influenza only when well matched to the circulating strains. However, antigenic drift can cause considerable mismatches b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0aaf8f19fab8daf9145b012346dd89
http://europepmc.org/articles/PMC6928577
http://europepmc.org/articles/PMC6928577
Autor:
Amy G Hise, Zachary Traylor, Noémi B Hall, Laura J Sutherland, Saidi Dahir, Megan E Ermler, Samuel Muiruri, Eric M Muchiri, James W Kazura, A Desirée LaBeaud, Charles H King, Catherine M Stein
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003584 (2015)
BACKGROUND:Multiple recent outbreaks of Rift Valley Fever (RVF) in Africa, Madagascar, and the Arabian Peninsula have resulted in significant morbidity, mortality, and financial loss due to related livestock epizootics. Presentation of human RVF vari
Externí odkaz:
https://doaj.org/article/90d06a3312884e9ebda116f6c8a2cdda
Autor:
Ariana Hirsh, Florian Krammer, Ana Fernandez-Sesma, Teddy John Wohlbold, Jonathan A. Runstadler, Mena Mansour, Megan E. Ermler, Irene Ramos
Publikováno v:
Emerging Infectious Diseases, Vol 21, Iss 7, Pp 1197-1201 (2015)
Emerging Infectious Diseases
Emerging Infectious Diseases
Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b24655d22fe274476421e215ab2867a
https://doi.org/10.3201/eid2107.141755
https://doi.org/10.3201/eid2107.141755
Autor:
Rong Hai, Fatima Amanat, Peter Palese, Florian Krammer, Ericka Kirkpatrick, Veronika Chromikova, Weina Sun, Megan E. Ermler
Publikováno v:
Journal of virology, vol 91, iss 12
Seasonal influenza virus epidemics represent a significant public health burden. Approximately 25% of all influenza virus infections are caused by type B viruses, and these infections can be severe, especially in children. Current influenza virus vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9197f9a4f38b6734b9051c36f21cc775
https://escholarship.org/uc/item/6nn757b5
https://escholarship.org/uc/item/6nn757b5
Publikováno v:
Journal of virology, vol 90, iss 7
A panel of influenza A viruses expressing chimeric hemagglutinins (cHA) with intragroup or intergroup head/stalk combinations was generated. Viruses were characterized for growth kinetics and preservation of stalk epitopes. With a few notable excepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6946580eda372e03813a66e1e796d831
https://pubmed.ncbi.nlm.nih.gov/26764009
https://pubmed.ncbi.nlm.nih.gov/26764009
Autor:
Amy G. Hise, Stefan A. Schattgen, Katherine A. Fitzgerald, Sivapriya Kailasan Vanaja, Zachary Traylor, Megan E. Ermler, Krupen Patel
Inflammasome activation is gaining recognition as an important mechanism for protection during viral infection. Here, we investigate whether Rift Valley fever virus, a negative-strand RNA virus, can induce inflammasome responses and IL-1β processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7ea27f7cf9c63b8a90b542bc7929e7
https://europepmc.org/articles/PMC3951897/
https://europepmc.org/articles/PMC3951897/