Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Megan E. Buechel"'
Autor:
Catherine H. Watson, Ramez N. Eskander, Ronald D. Alvarez, Kimberly Levinson, Chad M. Michener, Laura M. Chambers, Megan E. Buechel, Meng Yao, A.M. Jernigan
Publikováno v:
Gynecologic Oncology Reports
Gynecologic Oncology Reports, Vol 36, Iss, Pp 100755-(2021)
Gynecologic Oncology Reports, Vol 36, Iss, Pp 100755-(2021)
Highlights • 30.6% of responding gynecologic oncologists reported assignment of authorship that did not meet ICMJE criteria. • The majority reported that ICMJE criteria were generalizable, helpful and considered non-adherence as scientific miscon
Publikováno v:
Current Obstetrics and Gynecology Reports. 7:20-27
The aim of this study is to discuss the background of PARP inhibitors and to provide an overview of the utility of these drugs for treatment of epithelial ovarian cancer. Numerous phase I–III trials are presented within the manuscript that outline
Autor:
Raoul Tibes, James L. Slack, James M Bogenberger, Megan E. Buechel, Ruben A. Mesa, R. Tanner Hagelstrom, David O. Azorsa, Hongwei H. Yin, Shilpi Arora, Donald Chow, Esteban Braggio, Tim Demuth, Leena Chaudhuri, Irma M. Gonzales
Publikováno v:
Blood
To identify rational therapeutic combinations with cytarabine (Ara-C), we developed a high-throughput, small-interference RNA (siRNA) platform for myeloid leukemia cells. Of 572 kinases individually silenced in combination with Ara-C, silencing of 10
Publikováno v:
Open Forum Infectious Diseases
Autor:
Shilpi Arora, James M Bogenberger, Craig B. Reeder, Tim Demuth, Megan E. Buechel, Irma M. Gonzales, Ruben A. Mesa, James L. Slack, Donald Chow, Raoul Tibes, Pierre Noel, Esteban Braggio, Amanda McNally, Leena Chaudhuri, Tanner R Hagelstrom, David O. Azorsa, Hongwei Yin
Publikováno v:
Blood. 118:229-229
Abstract 229 Introduction: Optimal rational combination targets with Cytarabine (AraC) have not been identified. After the development of a high-throughput, small-interfering RNA (siRNA) platform for suspension cells, we performed the first RNAi sens
Autor:
James Bogenberger, Megan E. Buechel, Raoul Tibes, R. Tanner Hagelstrom, David O. Azorsa, Keerthi Bhagavatula
Publikováno v:
Cancer Research. 70:LB-127
Cytarabine is the backbone of therapy for acute myeloid leukemia (AML) patients, yet due to a high incidence of relapse and treatment-related complications novel, less toxic treatment regimens incorporating AraC need to be designed. To increase the t
Publikováno v:
Molecular Cancer Therapeutics. 8:A202-A202
Therapies and outcomes of patients with Acute Myeloid Leukemia (AML) and advanced myelodysplastic syndrome (MDS) remain very poor and AML is one of the deadliest cancers in relation to incidence. Mostly, because critical targets regulating myeloid ce
Autor:
David Azrosa, Raoul Tibes, Tanner Hagelstrom, Ashish Choudhary, Megan E. Buechel, Keertivibha Bhagavatula, James Bogenberger
Publikováno v:
Blood. 114:590-590
Abstract 590 Background: To improve response and increase the number of patients responding to Ara-C, new genes/mechanisms/pathways need to be discovered that underlie and determine the sensitivity to Ara-C. We hypothesized that applying synthetic le