Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Megan E Cavanaugh"'
Autor:
Hui Zheng, Eirini Pectasides, Mohamed Uduman, Charles S Fuchs, James M Cleary, Adam J Bass, Jérémy Augustin, Leonie K de Klerk, Anuj K Patel, Sarah Derks, Nihal Raman, Fahire G Akarca, Nadine J McCleary, Douglas A Rubinson, Jeffrey W Clark, Bridget Fitzpatrick, Lauren K Brais, Megan E Cavanaugh, Amanda J Rode, Melissa G Jean, Patrick H Lizotte, Matthew J Nazzaro, Peter C Enzinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/88b5dffda1124385a9d172a7073bce20
Autor:
Mark M. Awad, Yvan Le Bruchec, Brian Lu, Jason Ye, Julie Ann Miller, Patrick H. Lizotte, Megan E. Cavanaugh, Amanda J. Rode, Calin Dan Dumitru, Alexander Spira
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/3963600921ff4ed4ab2f25dbc17d9408
Autor:
Mark M. Awad, Yvan Le Bruchec, Brian Lu, Jason Ye, JulieAnn Miller, Patrick H. Lizotte, Megan E. Cavanaugh, Amanda J. Rode, Calin Dan Dumitru, Alexander Spira
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundHistone deacetylase (HDAC) overexpression has been documented in various cancers and may be associated with worse outcomes. Data from early-phase studies of advanced non-small cell lung cancer (NSCLC) suggest encouraging antitumor activity
Externí odkaz:
https://doaj.org/article/160fc0cc01ca4eaabcc5f6f2e25cfe6a
Autor:
Pasi A. Jänne, David A. Barbie, Nathanael S. Gray, Paul T. Kirschmeier, Mark Bittinger, Mari Kuraguchi, Hsiang-Fong Kao, Erica Fitzpatrick, Lauren Badalucco, Meghana Kulkarni, Aaron Yang, Naomi Mayman, Abha Dhaneshwar, Stephen Wang, Luke J. Taus, Megan E. Cavanaugh, Troy A. Luster, Ruey-Long Hong, Patrick H. Lizotte
Table 1 compound list
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2ef21b2575a2f8eedd65cee7b044db
https://doi.org/10.1158/2326-6066.22539421.v1
https://doi.org/10.1158/2326-6066.22539421.v1
Autor:
Pasi A. Jänne, David A. Barbie, Nathanael S. Gray, Paul T. Kirschmeier, Mark Bittinger, Mari Kuraguchi, Hsiang-Fong Kao, Erica Fitzpatrick, Lauren Badalucco, Meghana Kulkarni, Aaron Yang, Naomi Mayman, Abha Dhaneshwar, Stephen Wang, Luke J. Taus, Megan E. Cavanaugh, Troy A. Luster, Ruey-Long Hong, Patrick H. Lizotte
We developed a screening assay in which luciferized ID8 expressing OVA was cocultured with transgenic CD8+ T cells specifically recognizing the model antigen in an H-2b–restricted manner. The assay was screened with a small-molecule library to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ad3797aa3be0a0555e8bfa1e8f6433
https://doi.org/10.1158/2326-6066.c.6549088.v1
https://doi.org/10.1158/2326-6066.c.6549088.v1
Autor:
Pasi A. Jänne, David A. Barbie, Nathanael S. Gray, Paul T. Kirschmeier, Mark Bittinger, Mari Kuraguchi, Hsiang-Fong Kao, Erica Fitzpatrick, Lauren Badalucco, Meghana Kulkarni, Aaron Yang, Naomi Mayman, Abha Dhaneshwar, Stephen Wang, Luke J. Taus, Megan E. Cavanaugh, Troy A. Luster, Ruey-Long Hong, Patrick H. Lizotte
Table 3 SCCHN clinical info
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e88b2af0abdaf8346e63652bed3b82e
https://doi.org/10.1158/2326-6066.22539415.v1
https://doi.org/10.1158/2326-6066.22539415.v1
Autor:
Pasi A. Jänne, David A. Barbie, Nathanael S. Gray, Paul T. Kirschmeier, Mark Bittinger, Mari Kuraguchi, Hsiang-Fong Kao, Erica Fitzpatrick, Lauren Badalucco, Meghana Kulkarni, Aaron Yang, Naomi Mayman, Abha Dhaneshwar, Stephen Wang, Luke J. Taus, Megan E. Cavanaugh, Troy A. Luster, Ruey-Long Hong, Patrick H. Lizotte
Suppl. Fig. 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116eda75ff5e04c968b2c8134580121e
https://doi.org/10.1158/2326-6066.22539424
https://doi.org/10.1158/2326-6066.22539424
Supplementary Data from CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Autor:
Kwok-Kin Wong, Nathanael S. Gray, David A. Barbie, Geoffrey I. Shapiro, Haribabu Arthanari, Norman E. Sharpless, W. Nicholas Haining, Jerome Ritz, Gordon J. Freeman, Sangeetha Palakurthi, Raphael Bueno, Genevieve M. Boland, Viswanath Gunda, Sareh Parangi, Jochen H. Lorch, William G. Richards, Jay C. Strum, Patrick J. Roberts, Eric Haines, Amanda J. Rode, Megan E. Cavanaugh, Ting Chen, Peng Gao, Hua Zhang, Yanxi Zhang, Annan Yang, Lauren E. Bufe, Max M. Quinn, Ashley A. Merlino, Patrick H. Lizotte, John E. Bisi, Jessica A. Sorrentino, Grit S. Herter-Sprie, Chensheng W. Zhou, Michaela Bowden, Cloud P. Paweletz, Elena Ivanova, Amir R. Aref, Hongye Liu, Wei Huang, Sandeep Chhabra, Kathleen Yates, Ruben Dries, Shuai Li, Russell W. Jenkins, Eric S. Wang, Jiehui Deng
Figure S1. Characterization of cells and CDK4/6 inhibitors; Figure S2. CDK6 phosphorylates serine residues of the regulatory domain of NFAT4 (NFATc3); Figure S3. Analysis of lung tumor immune infiltrates after CDK4/6 inhibition from KrasG12D (Kras),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a01c7e72b06ed917fff29065c873f6
https://doi.org/10.1158/2159-8290.22531849.v1
https://doi.org/10.1158/2159-8290.22531849.v1
Autor:
Pasi A. Jänne, David A. Barbie, Nathanael S. Gray, Paul T. Kirschmeier, Mark Bittinger, Mari Kuraguchi, Hsiang-Fong Kao, Erica Fitzpatrick, Lauren Badalucco, Meghana Kulkarni, Aaron Yang, Naomi Mayman, Abha Dhaneshwar, Stephen Wang, Luke J. Taus, Megan E. Cavanaugh, Troy A. Luster, Ruey-Long Hong, Patrick H. Lizotte
Table 2 sgRNA genes and sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af50c3bbcaeabc11a1d4fd1caea5f2ac
https://doi.org/10.1158/2326-6066.22539418
https://doi.org/10.1158/2326-6066.22539418
Autor:
Robert I. Haddad, Ravindra Uppaluri, Ann Marie Egloff, Cloud P. Paweletz, Megan E. Cavanaugh, Anupam M. Desai, Peter C. Everett, Roy B. Tishler, Danielle N. Margalit, Jonathan D. Schoenfeld, Jochen H. Lorch, Rosh K.V. Sethi, Eleni M. Rettig, Jason I. Kass, Laura A. Goguen, Donald J. Annino, Patrick H. Lizotte, Michelle Flynn, Jennifer M. Cutler, Charles T. Quinn, Vickie Y. Jo, Kristine Wong, Kee-Young Shin, Anne O'Neill, Glenn J. Hanna
Purpose:Surgery often represents the best chance for disease control in locoregionally recurrent squamous cell carcinoma of the head and neck (SCCHN). We investigated dual immune-checkpoint inhibition [anti–PD-1, nivolumab (N), and anti-KIR, lirilu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf420cd615480116b990e2ed61fcdd0
https://doi.org/10.1158/1078-0432.c.6530928.v1
https://doi.org/10.1158/1078-0432.c.6530928.v1