Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Megan E Callaghan"'
Publikováno v:
The Journal of Climate Change and Health, Vol 19, Iss , Pp 100335- (2024)
Introduction: Due to climate change, the frequency of heatwaves and extreme heat events (EHE) has increased over the last five decades and is expected to continue increasing. Methods: In this scoping review, we searched the literature for how EHEs an
Externí odkaz:
https://doaj.org/article/01bd2bc4effe4bf49bc8f5e974a8a2cd
Autor:
Elizabeth A. Tovar, Menusha Arumugam, Curt J. Essenburg, Patrick S. Dischinger, Jamie L. Grit, Megan E. Callaghan, Rachael T.C. Sheridan, Lisa Turner, Corinne R. Esquibel, Kristin Feenstra, Zachary B. Madaj, Ian Beddows, Carrie R. Graveel, Matthew R. Steensma
SUMMARYThe tumor suppressorNF1is a critical driver of sporadic breast cancer and NF-related breast cancers. We utilized distinctNf1-deficient immunocompetent rat models to investigateNf1function in mammary development and homeostasis. Here we demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfaeb31454a06235dbe01a259f0796f1
https://doi.org/10.1101/2022.12.22.520633
https://doi.org/10.1101/2022.12.22.520633
Autor:
Matthew Steensma, Curt J. Essenburg, Megan E. Callaghan, Menusha Arumugam, Elizabeth A. Tovar, Carrie R. Graveel, Rachael Sheridan, Patrick S. Dischinger
Publikováno v:
Bio Protoc
With the advent of CRISPR-Cas and the ability to easily modify the genome of diverse organisms, rat models are being increasingly developed to interrogate the genetic events underlying mammary development and tumorigenesis. Protocols for the isolatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f64b1b2df96837ea4a8ef906d15ec5
https://europepmc.org/articles/PMC7842324/
https://europepmc.org/articles/PMC7842324/
Autor:
Tristan Kempston, Megan E. Callaghan, Curt J. Essenburg, Eve E. Gardner, Roderick T. Bronson, Elizabeth A. Tovar, Ashley N. Turner, Bryn Eagleson, Anil K. Challa, Zachary Madaj, Matthew Steensma, Megan J. Bowman, Robert A. Kesterson, Carrie R. Graveel, Patrick S. Dischinger
Publikováno v:
NPJ Breast Cancer
npj Breast Cancer, Vol 4, Iss 1, Pp 1-14 (2018)
npj Breast Cancer, Vol 4, Iss 1, Pp 1-14 (2018)
The key negative regulatory gene of the RAS pathway, NF1, is mutated or deleted in numerous cancer types and is associated with increased cancer risk and drug resistance. Even though women with neurofibromatosis (germline NF1 mutations) have a substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba9909f4a2d4dd60a54f50da808449d
https://doi.org/10.1038/s41523-018-0080-8
https://doi.org/10.1038/s41523-018-0080-8
Autor:
Zachary Madaj, Curt J. Essenburg, Patrick S. Dischinger, Robert A. Kesterson, Matthew Steensma, Tristan Kempston, Elizabeth A. Tovar, Ashley N. Turner, Carrie R. Graveel, Eve E. Gardner, Megan J. Bowman, Bryn Eagleson, Megan E. Callaghan, Anil K. Challa, Roderick T. Bronson
Publikováno v:
Molecular Cancer Research. 16:B43-B43
Neurofibromatosis type 1 (NF1) is a common tumor predisposition syndrome caused by germline mutations in the NF1 gene that affects1 in 3,000 births. The NF1 gene encodes for neurofibromin, a GTPase that negatively regulates RAS. Women with NF1 have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10ac4b3c7c4cced9d4342b0e40695d7
https://doi.org/10.1158/1557-3125.advbc17-b43
https://doi.org/10.1158/1557-3125.advbc17-b43
Autor:
Albert T. Anastasio, Anthony N. Baumann, Megan E. Callaghan, Kempland C. Walley, Davin C. Gong, Grayson M. Talaski, Keegan T. Conry, Cole Shafer, Jacob C. Hoffmann
Publikováno v:
Prosthesis, Vol 6, Iss 3, Pp 582-595 (2024)
The surgical management of adult spinal deformities (ASDs) involves a wide variety of complex and technically challenging operative techniques. Despite numerous publications examining the relationship between surgeon experience and outcomes in ASD, n
Externí odkaz:
https://doaj.org/article/7fc05fa68f894a21bbc5ce6c9aa0170e