Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Megan E, McBee"'
Autor:
Nick K. Davis, Yok Hian Chionh, Megan E. McBee, Fabian Hia, Duanduan Ma, Liang Cui, Mariam Lucila Sharaf, Weiling Maggie Cai, Watthanachai Jumpathong, Stuart S. Levine, Sylvie Alonso, Peter C. Dedon
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Mycobacteria adapt to infection stresses by entering a reversible non-replicating persistence (NRP) with slow or no cell growth and broad antimicrobial tolerance. Hypoxia and nutrient deprivation are two well-studied stresses commonly used t
Externí odkaz:
https://doaj.org/article/f8fddf70d57c4a719df9e9dd98168d53
Autor:
Patthara Kongsuphol, Huan Jia, Hoi Lok Cheng, Yue Gu, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Sing Mei Lim, Say Yong Ng, Paul Ananth Tambyah, Haziq Nasir, Xiaohong Gao, Dousabel Tay, Seunghyeon Kim, Rashi Gupta, Xinlei Qian, Mary M. Kozma, Kiren Purushotorman, Megan E. McBee, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-12 (2021)
Kongsuphol et al. develop a paper-based, vertical flow assay to detect SARS-CoV-2 neutralizing antibodies. The point-of-care assay has comparable performance to lab-based tests and provides results in 10 min.
Externí odkaz:
https://doaj.org/article/663f8b27aead4a418e60988c13e46a00
Autor:
Hoi Lok Cheng, Sing Mei Lim, Huan Jia, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Patrina W. L. Chua, Abirami R., Sharon Y. H. Ling, Megan E. McBee, Barnaby E. Young, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT As the COVID-19 pandemic continues, countries around the world are switching toward vaccinations and boosters to combat the pandemic. However, waning immunity against SARS-CoV-2 wild-type (WT) and variants have been widely reported. Booster
Externí odkaz:
https://doaj.org/article/6651f04433e54122ae0f8bff3b6af7b6
Autor:
Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P. Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Megan E. McBee, Barnaby E. Young, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract There is clinical need for a quantifiable point‐of‐care (PoC) SARS‐CoV‐2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing landscape. Here, we present a rapid and semi‐quantitative nAb test that uses f
Externí odkaz:
https://doaj.org/article/d63c818224ae4a54916797daab64c017
Autor:
Huan Jia, Eric A. Miller, Chia Ching Chan, Say Yong Ng, Mookkan Prabakaran, Meng Tao, Ian Shen-Yi Cheong, Sing Mei Lim, Ming Wei Chen, Xiaohong Gao, Abirami R., Megan E. McBee, Peter R. Preiser, Hadley D. Sikes, Patthara Kongsuphol
Publikováno v:
Lab on a Chip. 22:1321-1332
Surveillance of SARS-CoV-2 infection is critical for controlling the current pandemic. Antigen rapid tests (ARTs) provide a means for surveillance. Available lateral flow assay format ARTs rely heavily on nitrocellulose paper, raising challenges in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d3f311bf015311a086866fdcf80dd4
https://doi.org/10.1039/d2lc00073c
https://doi.org/10.1039/d2lc00073c
Autor:
Emma H. Yee, Eric A. Miller, Yining Hao, Peter R. Preiser, Dousabel M Y Tay, Patthara Kongsuphol, Huan Jia, Seunghyeon Kim, Megan E. McBee, Hadley D. Sikes
Publikováno v:
ACS Sensors
Rapid and inexpensive serological tests for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibodies are essential to conduct large-scale seroprevalence surveys and can potentially complement nucleic acid or antigen tests at the point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b373e4d189676f2bd153aa65c2f1ad38
https://doi.org/10.1021/acssensors.1c00235
https://doi.org/10.1021/acssensors.1c00235
Autor:
Barnaby Edward Young, Megan E. McBee, Joyti Somani, Rachel Lim, S. P. Heussler, Hadley D. Sikes, Sharmila Sengupta, Peter R. Preiser, Wei Chen Ming, Patthara Kongsuphol, Bhuvaneshwari D, Say Yong Ng, Xiaohong Gao, Hoi Lok Cheng, O Shunmuganath, Shuvan Prashant Turaga, Paul A. MacAry, Jia Huan, Dousabel M Y Tay
There is clinical need for a quantifiable point-of-care (PoC) SARS-CoV-2 neutralizing antibody (nAb) test that is adaptable with the pandemic’s changing landscape. Here, we present a rapid and semi-quantitative nAb test that uses finger stick or ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4c5b5b1bac47dfdc3ea276cad6c7040
https://doi.org/10.1101/2021.11.11.21266241
https://doi.org/10.1101/2021.11.11.21266241
Autor:
Hoi Lok Cheng, Peter R. Preiser, O Shunmuganathan, Hadley D. Sikes, Haziq Nasir, Patthara Kongsuphol, Mary M Kozma, Paul Ananth Tambyah, Bhuvaneshwari D, Megan E. McBee, Seunghyeon Kim, Xiaohong Gao, Say Yong Ng, Paul A. MacAry, Dousabel M Y Tay, Kiren Purushotorman, Rashi Gupta, Sing Mei Lim, Huan Jia, Xinlei Qian, Yue Gu, Ming Wei Chen
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-12 (2021)
Neutralizing antibodies (NAbs) prevent pathogens from infecting host cells. Detection of SARS-CoV-2 NAbs is critical to evaluate herd immunity and monitor vaccine efficacy against SARS-CoV-2, the virus that causes COVID-19. All currently available NA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a9cf09bca18d0e4f9dc5edb026d284
https://doi.org/10.1038/s43856-021-00045-9
https://doi.org/10.1038/s43856-021-00045-9
Autor:
Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P. Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M. Y. Tay, Megan E. McBee, Barnaby E. Young, Paul A. MacAry, Hadley D. Sikes, Peter R. Preiser
Publikováno v:
Bioengineeringtranslational medicine. 7(2)
There is clinical need for a quantifiable point-of-care (PoC) SARS-CoV-2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing landscape. Here, we present a rapid and semi-quantitative nAb test that uses finger stick or veno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14deff7869c27665dba97f84b9f60779
https://pubmed.ncbi.nlm.nih.gov/35600666
https://pubmed.ncbi.nlm.nih.gov/35600666
Autor:
Kalyan Kumar Pasunooti, Pooja Gopal, Shanmugavel Gnanakalai, Nelson B. Olivier, Siau Hoi Lim, Julien Lescar, Seetharamsing Balamkundu, Vinod Gadi, Wenhe Zhong, Peter C. Dedon, Chuan-Fa Liu, Yok Hian Chionh, Ed T. Buurman, Thomas Dick, Megan E. McBee, Qianhui Nah, Yee Hwa Wong
Publikováno v:
Journal of Medicinal Chemistry. 62:7788-7805
Among the >120 modified ribonucleosides in the prokaryotic epitranscriptome, many tRNA modifications are critical to bacterial survival, which makes their synthetic enzymes ideal targets for antibiotic development. Here we performed a structure-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550e33b18ac78640a1f11420a6243e12
https://doi.org/10.1021/acs.jmedchem.9b00582
https://doi.org/10.1021/acs.jmedchem.9b00582