Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Megan E, Brasch"'
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 2, p e1006732 (2019)
We seek to characterize the motility of mouse fibroblasts on 2D substrates. Utilizing automated tracking techniques, we find that cell trajectories are super-diffusive, where displacements scale faster than t1/2 in all directions. Two mechanisms have
Externí odkaz:
https://doaj.org/article/9ee93c392e704afaa4d792f1233983f2
Autor:
Megan E Brasch, Giuseppe Passucci, Anushree C Gulvady, Christopher E Turner, M Lisa Manning, James H Henderson
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211408 (2019)
Cell motility is critical to biological processes from wound healing to cancer metastasis to embryonic development. The involvement of organelles in cell motility is well established, but the role of organelle positional reorganization in cell motili
Externí odkaz:
https://doaj.org/article/7a6d0aee5b9a4e8a9029da4fe5934192
Publikováno v:
Medicalbiological engineeringcomputing. 59(9)
In vitro cell culture model systems often employ monocultures, despite the fact that cells generally exist in a diverse, heterogeneous microenvironment in vivo. In response, heterogeneous cultures are increasingly being used to study how cell phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4917d4d9590582ae2deeeb52e035c519
https://pubmed.ncbi.nlm.nih.gov/34331635
https://pubmed.ncbi.nlm.nih.gov/34331635
Publikováno v:
Biomaterials. 140:150-161
In vitro biomaterial models have enabled advances in understanding the role of extracellular matrix (ECM) architecture in the control of cell motility and polarity. Most models are, however, static and cannot mimic dynamic aspects of in vivo ECM remo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da27662d48328b3369a1c100b2ee57aa
https://doi.org/10.1016/j.biomaterials.2017.06.016
https://doi.org/10.1016/j.biomaterials.2017.06.016
Publikováno v:
ACS Applied Materials & Interfaces. 9:22176-22184
Material stiffness has been shown to have potent effects on bacterial attachment and biofilm formation, but the mechanism is still unknown. In this study, response to material stiffness by Escherichia coli during attachment was investigated with biof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d7b5ad7db0538dcf448bb0c12998ff
https://doi.org/10.1021/acsami.7b04757
https://doi.org/10.1021/acsami.7b04757
Publikováno v:
Journal of materials science. Materials in medicine. 28(10)
The ability of a three-dimensional scaffold to support cell seeding prior to implantation is a critical criterion for many scaffold-based tissue engineering and regenerative medicine strategies. Shape memory polymer functionality may present importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80ebd097d966179440f551f539d09c0
https://pubmed.ncbi.nlm.nih.gov/28861660
https://pubmed.ncbi.nlm.nih.gov/28861660
Publikováno v:
Scientific Reports
Bacterial response to surface topography during biofilm formation was studied using 5 μm tall line patterns of poly (dimethylsiloxane) (PDMS). Escherichia coli cells attached on top of protruding line patterns were found to align more perpendicularl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8d3771330c794ea8921cd11b8c9ac4
https://doi.org/10.1038/srep29516
https://doi.org/10.1038/srep29516
Autor:
Megan E. Brasch, Nicholas O. Deakin, M. L. Manning, James H. Henderson, Christopher E. Turner
Publikováno v:
2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC).
Dynamic reorganization of a cell's local microenvironment has been shown to critically alter migration, adhesion, and morphological behaviors in vivo during development, wound healing, and disease. While static microenvironments with patterned topogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd2694f38243da1dd082c5812b5d447d
https://doi.org/10.1109/nebec.2015.7117055
https://doi.org/10.1109/nebec.2015.7117055
Publikováno v:
2013 39th Annual Northeast Bioengineering Conference.
Cellular tracking has been employed to investigate complex cell-cell and cell-material interactions that play critical roles in tissue development and disease progression. Tracking is often performed manually, however limitations associated with manu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::318e761f79a6b627e779684e158a094f
https://doi.org/10.1109/nebec.2013.158
https://doi.org/10.1109/nebec.2013.158
Publikováno v:
2012 38th Annual Northeast Bioengineering Conference (NEBEC).
Due to a recent focus on cell based therapies in biomedical applications, the ability to accurately track cellular behavior has become an increasingly crucial research tool. Cell motility is of particular importance as it influences basic cellular in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7e1107d79c5eb1557de56a1c6e3c16
https://doi.org/10.1109/nebc.2012.6207056
https://doi.org/10.1109/nebc.2012.6207056