Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Megan D. McRae"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Atrial fibrillation (AF) is associated with electrical and structural remodeling in the atria; however, the regional and temporal progression of atrial remodeling is incompletely understood. The objective of this study was to investigate the regional
Externí odkaz:
https://doaj.org/article/d57670ab8f884bc9a57a97d2be6eb5f7
Autor:
Martin Mackasey, BSc, Emmanuel E. Egom, MD, PhD, Hailey J. Jansen, PhD, Rui Hua, PhD, Motahareh Moghtadaei, PhD, Yingjie Liu, PhD, Jaspreet Kaur, PhD, Megan D. McRae, BHSc, Oleg Bogachev, MD, Sara A. Rafferty, MSc, Gibanananda Ray, PhD, Adam W. Kirkby, MSc, Robert A. Rose, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 824-843 (2018)
Summary: Sinoatrial node (SAN) disease mechanisms are poorly understood, and therapeutic options are limited. Natriuretic peptide(s) (NP) are cardioprotective hormones whose effects can be mediated partly by the NP receptor C (NPR-C). We investigated
Externí odkaz:
https://doaj.org/article/3896d8b4ee5d40c586211913311ef884
Autor:
Loryn J. Bohne, Hailey J. Jansen, Tristan W. Dorey, Irene M. Daniel, K. Lockhart Jamieson, Darrell D. Belke, Megan D. McRae, Robert A. Rose
Publikováno v:
JACC: Basic to Translational Science.
Autor:
Hailey J. Jansen, Megan D McRae, Robert A. Rose, Darrell D. Belke, Logan Atkinson, Tristan W. Dorey, Martin Mackasey, Loryn J. Bohne, Yingjie Liu
Publikováno v:
Cardiovasc Res
Aims Heart rate (HR) is a critical indicator of cardiac performance that is determined by sinoatrial node (SAN) function and regulation. Natriuretic peptides, including C-type NP (CNP), have been shown to modulate ion channel function in the SAN when
Autor:
Oleg Bogachev, Sara A. Rafferty, Yingjie Liu, Rui Hua, Hailey J. Jansen, Megan D. McRae, Motahareh Moghtadaei, Robert A. Rose, Adam W. Kirkby, Jaspreet Kaur, Gibanananda Ray, Emmanuel E. Egom, Martin Mackasey
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 824-843 (2018)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • SAN disease is prevalent in hypertension and heart failure and can be induced by chronic Ang II treatment in mice. • Ang II caused SAN disease in mice in association with impaired electrical conduction, reduction
Highlights • SAN disease is prevalent in hypertension and heart failure and can be induced by chronic Ang II treatment in mice. • Ang II caused SAN disease in mice in association with impaired electrical conduction, reduction