Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Megan D. Joseph"'
Publikováno v:
Open Biology, Vol 13, Iss 5 (2023)
Upon initial immune challenge, dendritic cells (DCs) migrate to lymph nodes and interact with fibroblastic reticular cells (FRCs) via C-type lectin-like receptor 2 (CLEC-2). CLEC-2 binds to the membrane glycoprotein podoplanin (PDPN) on FRCs, inhibit
Externí odkaz:
https://doaj.org/article/ed468f6c1388465daedb3726df30ee90
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1503 (2021)
G-protein coupled receptors (GPCRs) are known to form homo- and hetero- oligomers which are considered critical to modulate their function. However, studying the existence and functional implication of these complexes is not straightforward as contro
Externí odkaz:
https://doaj.org/article/f676f1d555da460aa101b0425dab467d
Autor:
Elena Tomas Bort, Megan D Joseph, Qiaoying Wang, Edward P Carter, Nicolas J Roth, Jessica Gibson, Ariana Samadi, Hemant M Kocher, Sabrina Simoncelli, Peter J McCormick, Richard P Grose
Publikováno v:
eLife. 12
Pancreatic ductal adenocarcinoma (PDAC) continues to show no improvement in survival rates. One aspect of PDAC is elevated ATP levels, pointing to the purinergic axis as a potential attractive therapeutic target. Mediated in part by highly druggable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc000a1a7f512c2378df22dbb610351
https://doi.org/10.7554/elife.86971
https://doi.org/10.7554/elife.86971
Autor:
Elena Tomas Bort, Megan D Joseph, Qiaoying Wang, Edward P Carter, Nicolas J Roth, Jessica Gibson, Ariana Samadi, Hemant M Kocher, Sabrina Simoncelli, Peter J McCormick, Richard P Grose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a70d3d0bfb74162566fd76cbe1cbe50
https://doi.org/10.7554/elife.86971.sa2
https://doi.org/10.7554/elife.86971.sa2
Autor:
Elena Tomas Bort, Megan D. Joseph, Qiaoying Wang, Edward P. Carter, Nicolas J. Roth, Jessica Gibson, Ariana Samadi, Hemant M. Kocher, Sabrina Simoncelli, Peter J. McCormick, Richard P. Grose
Pancreatic ductal adenocarcinoma (PDAC) is a cancer of unmet clinical need. Given the elevated ATP levels seen in PDAC, the purinergic axis represents an attractive therapeutic target. Mediated in part by highly druggable extracellular proteins, it p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bebb4e9c69b9b0cc5e34edcf6c975af
https://doi.org/10.1101/2022.10.24.513477
https://doi.org/10.1101/2022.10.24.513477
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 1503, p 1503 (2021)
Biomolecules; Volume 11; Issue 10; Pages: 1503
Biomolecules, Vol 11, Iss 1503, p 1503 (2021)
Biomolecules; Volume 11; Issue 10; Pages: 1503
G-protein coupled receptors (GPCRs) are known to form homo- and hetero- oligomers which are considered critical to modulate their function. However, studying the existence and functional implication of these complexes is not straightforward as contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eac3cf76e65d43ff6e47156fb305006
http://europepmc.org/articles/PMC8533726
http://europepmc.org/articles/PMC8533726