Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Megan D. Fesinmeyer"'
Autor:
Sarah A Pendergrass, Steven Buyske, Janina M Jeff, Alex Frase, Scott Dudek, Yuki Bradford, Jose-Luis Ambite, Christy L Avery, Petra Buzkova, Ewa Deelman, Megan D Fesinmeyer, Christopher Haiman, Gerardo Heiss, Lucia A Hindorff, Chun-Nan Hsu, Rebecca D Jackson, Yi Lin, Loic Le Marchand, Tara C Matise, Kristine R Monroe, Larry Moreland, Kari E North, Sungshim L Park, Alex Reiner, Robert Wallace, Lynne R Wilkens, Charles Kooperberg, Marylyn D Ritchie, Dana C Crawford
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226771 (2019)
We performed a hypothesis-generating phenome-wide association study (PheWAS) to identify and characterize cross-phenotype associations, where one SNP is associated with two or more phenotypes, between thousands of genetic variants assayed on the Meta
Externí odkaz:
https://doaj.org/article/d1011295931b4e4fb3037f3c735bbbb4
Autor:
Christopher S Carlson, Tara C Matise, Kari E North, Christopher A Haiman, Megan D Fesinmeyer, Steven Buyske, Fredrick R Schumacher, Ulrike Peters, Nora Franceschini, Marylyn D Ritchie, David J Duggan, Kylee L Spencer, Logan Dumitrescu, Charles B Eaton, Fridtjof Thomas, Alicia Young, Cara Carty, Gerardo Heiss, Loic Le Marchand, Dana C Crawford, Lucia A Hindorff, Charles L Kooperberg, PAGE Consortium
Publikováno v:
PLoS Biology, Vol 11, Iss 9, p e1001661 (2013)
The vast majority of genome-wide association study (GWAS) findings reported to date are from populations with European Ancestry (EA), and it is not yet clear how broadly the genetic associations described will generalize to populations of diverse anc
Externí odkaz:
https://doaj.org/article/fb8361ed09b5421bb29d267aed506f0f
Autor:
Ulrike Peters, Kari E North, Praveen Sethupathy, Steve Buyske, Jeff Haessler, Shuo Jiao, Megan D Fesinmeyer, Rebecca D Jackson, Lew H Kuller, Aleksandar Rajkovic, Unhee Lim, Iona Cheng, Fred Schumacher, Lynne Wilkens, Rongling Li, Keri Monda, Georg Ehret, Khanh-Dung H Nguyen, Richard Cooper, Cora E Lewis, Mark Leppert, Marguerite R Irvin, C Charles Gu, Denise Houston, Petra Buzkova, Marylyn Ritchie, Tara C Matise, Loic Le Marchand, Lucia A Hindorff, Dana C Crawford, Christopher A Haiman, Charles Kooperberg
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003171 (2013)
Genetic variants in intron 1 of the fat mass- and obesity-associated (FTO) gene have been consistently associated with body mass index (BMI) in Europeans. However, follow-up studies in African Americans (AA) have shown no support for some of the most
Externí odkaz:
https://doaj.org/article/cf25b343afb9492caa81e5d1271f0798
Autor:
Sarah A Pendergrass, Kristin Brown-Gentry, Scott Dudek, Alex Frase, Eric S Torstenson, Robert Goodloe, Jose Luis Ambite, Christy L Avery, Steve Buyske, Petra Bůžková, Ewa Deelman, Megan D Fesinmeyer, Christopher A Haiman, Gerardo Heiss, Lucia A Hindorff, Chu-Nan Hsu, Rebecca D Jackson, Charles Kooperberg, Loic Le Marchand, Yi Lin, Tara C Matise, Kristine R Monroe, Larry Moreland, Sungshim L Park, Alex Reiner, Robert Wallace, Lynn R Wilkens, Dana C Crawford, Marylyn D Ritchie
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003087 (2013)
Using a phenome-wide association study (PheWAS) approach, we comprehensively tested genetic variants for association with phenotypes available for 70,061 study participants in the Population Architecture using Genomics and Epidemiology (PAGE) network
Externí odkaz:
https://doaj.org/article/c6158d1a2b2546dfaf4fd8c71d1e4d61
Autor:
Christy L Avery, Praveen Sethupathy, Steven Buyske, Qianchuan He, Dan-Yu Lin, Dan E Arking, Cara L Carty, David Duggan, Megan D Fesinmeyer, Lucia A Hindorff, Janina M Jeff, Liviu Klein, Kristen K Patton, Ulrike Peters, Ralph V Shohet, Nona Sotoodehnia, Alicia M Young, Charles Kooperberg, Christopher A Haiman, Karen L Mohlke, Eric A Whitsel, Kari E North
Publikováno v:
PLoS Genetics, Vol 8, Iss 8, p e1002870 (2012)
The QT interval (QT) is heritable and its prolongation is a risk factor for ventricular tachyarrhythmias and sudden death. Most genetic studies of QT have examined European ancestral populations; however, the increased genetic diversity in African Am
Externí odkaz:
https://doaj.org/article/1ef7f714f0d94f5a84cdac1eaf2428c0
Autor:
Steven Buyske, Ying Wu, Cara L Carty, Iona Cheng, Themistocles L Assimes, Logan Dumitrescu, Lucia A Hindorff, Sabrina Mitchell, Jose Luis Ambite, Eric Boerwinkle, Petra Buzkova, Chris S Carlson, Barbara Cochran, David Duggan, Charles B Eaton, Megan D Fesinmeyer, Nora Franceschini, Jeffrey Haessler, Nancy Jenny, Hyun Min Kang, Charles Kooperberg, Yi Lin, Loic Le Marchand, Tara C Matise, Jennifer G Robinson, Carlos Rodriguez, Fredrick R Schumacher, Benjamin F Voight, Alicia Young, Teri A Manolio, Karen L Mohlke, Christopher A Haiman, Ulrike Peters, Dana C Crawford, Kari E North
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35651 (2012)
The Metabochip is a custom genotyping array designed for replication and fine mapping of metabolic, cardiovascular, and anthropometric trait loci and includes low frequency variation content identified from the 1000 Genomes Project. It has 196,725 SN
Externí odkaz:
https://doaj.org/article/502c705b03d04443920fc5a0d8ff7989
Autor:
Veronica Wendy Setiawan, Jeffrey Haessler, Fredrick Schumacher, Michele L Cote, Ewa Deelman, Megan D Fesinmeyer, Brian E Henderson, Rebecca D Jackson, Jens-S Vöckler, Lynne R Wilkens, Shagufta Yasmeen, Christopher A Haiman, Ulrike Peters, Loïc Le Marchand, Charles Kooperberg
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30390 (2012)
We examined the association between HNF1B variants identified in a recent genome-wide association study and endometrial cancer in two large case-control studies nested in prospective cohorts: the Multiethnic Cohort Study (MEC) and the Women's Health
Externí odkaz:
https://doaj.org/article/5bdf54c8c3b040f08cfe9297481e716a
Autor:
Steven Buyske, Lynne R. Wilkens, Sungshim L. Park, Petra Buzkova, Dana C. Crawford, Robert B. Wallace, Yi Lin, Charles Kooperberg, Gerardo Heiss, Christy L. Avery, Marylyn D. Ritchie, José Luis Ambite, Tara C. Matise, Scott M. Dudek, Janina M. Jeff, Chun-Nan Hsu, Larry W. Moreland, Alexander P. Reiner, Yuki Bradford, Sarah A. Pendergrass, Alex T. Frase, Kristine R. Monroe, Kari E. North, Christopher A. Haiman, Loic Le Marchand, Rebecca D. Jackson, Lucia A. Hindorff, Megan D. Fesinmeyer, Ewa Deelman
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226771 (2019)
PLoS ONE
PLoS ONE
We performed a hypothesis-generating phenome-wide association study (PheWAS) to identify and characterize cross-phenotype associations, where one SNP is associated with two or more phenotypes, between thousands of genetic variants assayed on the Meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59db74e8a22311ce58123633670db8ff
https://doaj.org/article/d1011295931b4e4fb3037f3c735bbbb4
https://doaj.org/article/d1011295931b4e4fb3037f3c735bbbb4
Publikováno v:
Health & Place. 38:82-88
Public parks are promoted as places that support physical activity (PA), but evidence of how park visitation contributes to overall PA is limited. This study observed adults living in the Seattle metropolitan area (n=671) for one week using accelerom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfd9f2e5bbdc2d278765f5ab7c7017b
https://doi.org/10.1016/j.healthplace.2016.01.004
https://doi.org/10.1016/j.healthplace.2016.01.004
Autor:
Megan D. Fesinmeyer, Holly M. Romero, Darren S. Migita, Coral N. Ringer, Karen Kelly, Wren Haaland, Michael G. Leu, Elaine Beardsley, James B. Johnson
Publikováno v:
Pediatrics. 141
OBJECTIVES: Seattle Children’s Hospital sought to optimize the value equation for neonatal jaundice patients by creating a standard care pathway. METHODS: An evidence-based pathway for management of neonatal jaundice was created. This included mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7a5c665d0b700e67070f81f1c71f43
https://doi.org/10.1542/peds.2016-1472
https://doi.org/10.1542/peds.2016-1472