Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Megan Crow"'
Autor:
Sara Ballouz, Risa Karakida Kawaguchi, Maria T. Pena, Stephan Fischer, Megan Crow, Leon French, Frank M. Knight, Linda B. Adams, Jesse Gillis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Genetic and environmental variation are key contributors during organism development, but the influence of minor perturbations or noise is difficult to assess. This study focuses on the stochastic variation in allele-specific expression that
Externí odkaz:
https://doaj.org/article/dbed84c7e6f645c68b35621128732694
Autor:
Zia Khan, Min Jung, Megan Crow, Rajat Mohindra, Vidya Maiya, Joshua S. Kaminker, David H. Hackos, G. Scott Chandler, Mark I. McCarthy, Tushar Bhangale
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Dose-limiting toxicities significantly impact the benefit/risk profile of many drugs. Whole genome sequencing (WGS) in patients receiving drugs with dose-limiting toxicities can identify therapeutic hypotheses to prevent these tox
Externí odkaz:
https://doaj.org/article/8203af64f2254efdb0211f8800973199
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Single cell RNA-sequencing analysis poses challenges in replication due to technical biases and analytic variability among bioinformatics pipelines. Here, Crow et al develop MetaNeighbor for measuring cell-type replication across datasets, and use it
Externí odkaz:
https://doaj.org/article/67fefc8fb1054363be1ef3aa5f0f083c
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1771-1781 (2016)
Chronic pain is a common and devastating condition that induces well-characterized changes in neurons and microglia. One major unanswered question is why these changes should persist long after the precipitating injury has healed. Here, we suggest th
Externí odkaz:
https://doaj.org/article/7d8bc14062e94249bfbb8c6ddcacaf20
Publikováno v:
Translational Issues in Psychological Science. 8:416-430
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf7becf415f9cc09f88c432316779305
https://doi.org/10.1037/tps0000327
https://doi.org/10.1037/tps0000327
Autor:
Hamsini Suresh, Megan Crow, Nikolas Jorstad, Rebecca Hodge, Ed Lein, Alexander Dobin, Trygve Bakken, Jesse Gillis
Enhanced cognitive function in humans is hypothesized to result from cortical expansion and increased cellular diversity. However, the mechanisms that drive these phenotypic differences remain poorly understood, in part due to the lack of high-qualit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fcb1b6cd6aa28676dc979b862590585
https://doi.org/10.1101/2022.09.20.508736
https://doi.org/10.1101/2022.09.20.508736
Autor:
Nikolas L. Jorstad, Janet H.T. Song, David Exposito-Alonso, Hamsini Suresh, Nathan Castro, Fenna M. Krienen, Anna Marie Yanny, Jennie Close, Emily Gelfand, Kyle J. Travaglini, Soumyadeep Basu, Marc Beaudin, Darren Bertagnolli, Megan Crow, Song-Lin Ding, Jeroen Eggermont, Alexandra Glandon, Jeff Goldy, Thomas Kroes, Brian Long, Delissa McMillen, Trangthanh Pham, Christine Rimorin, Kimberly Siletti, Saroja Somasundaram, Michael Tieu, Amy Torkelson, Katelyn Ward, Guoping Feng, William D. Hopkins, Thomas Höllt, C. Dirk Keene, Sten Linnarsson, Steven A. McCarroll, Boudewijn P. Lelieveldt, Chet C. Sherwood, Kimberly Smith, Christopher A. Walsh, Alexander Dobin, Jesse Gillis, Ed S. Lein, Rebecca D. Hodge, Trygve E. Bakken
Humans have unique cognitive abilities among primates, including language, but their molecular, cellular, and circuit substrates are poorly understood. We used comparative single nucleus transcriptomics in adult humans, chimpanzees, gorillas, rhesus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd84ef3c30ad5c4d3e1668391c681a3d
https://doi.org/10.1101/2022.09.19.508480
https://doi.org/10.1101/2022.09.19.508480
Autor:
Brauer, Megan Crow1, Foust, Michelle Singer2
Publikováno v:
Psi Chi Journal of Psychological Research. 2020Special Issue, Vol. 25, p291-300. 10p.
Publikováno v:
Nat Protoc
Single cell RNA-sequencing data have significantly advanced the characterization of cell type diversity and composition. However, cell type definitions vary across data and analysis pipelines, raising concerns about cell type validity and generalizab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf31bd34843c34cde4e99d5f935e60b
https://doi.org/10.1038/s41596-021-00575-5
https://doi.org/10.1038/s41596-021-00575-5
Autor:
Zia Khan, Min Jung, Megan Crow, Rajat Mohindra, Vidya Maiya, Joshua Kaminker, David Hackos, G. Scott Chandler, Mark McCarthy, Tushar Bhangale
Dose-limiting toxicities significantly impact the benefit/risk profile of many drugs. Whole genome sequencing (WGS) in patients receiving drugs with dose-limiting toxicities can identify therapeutic hypotheses to prevent these toxicities. Peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::475494e22eba51cbe498b2e4669edc38
https://doi.org/10.21203/rs.3.rs-1816977/v1
https://doi.org/10.21203/rs.3.rs-1816977/v1