Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Megan Cross"'
Autor:
Trisha O'Moore-Sullivan, Jody Paxton, Megan Cross, Srinivas Teppala, Viral Chikani, George Hopkins, Katie Wykes, Paul A Scuffham, Clinical and Operational Reference Group
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0279923 (2023)
ObjectiveBariatric surgery is an effective treatment for type 2 diabetes and morbid obesity. This paper analyses the clinical and patient-reported outcomes of patients treated through the Bariatric Surgery Initiative, a health system collaboration pr
Externí odkaz:
https://doaj.org/article/c3413c92c83443e6b604dcd9457aab50
Autor:
Andreas Hofmann, Sarah Preston, Megan Cross, H. M. P. Dilrukshi Herath, Anne Simon, Robin B. Gasser
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Analyses of replicates in sets of discrete data, typically acquired in multi-well plate formats, is a recurring task in many contemporary areas in the Life Sciences. The availability of accessible cross-platform data analysis tool
Externí odkaz:
https://doaj.org/article/7e27f05c91ca449c822f2ee2e984223f
Autor:
Megan Cross, Siji Rajan, Janine Chekaiban, Jake Saunders, Chloe Hamilton, Jeong-Sun Kim, Mark J. Coster, Robin B. Gasser, Andreas Hofmann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Owing to the key role of trehalose in pathogenic organisms, there has recently been growing interest in trehalose metabolism for therapeutic purposes. Trehalose-6-phosphate phosphatase (TPP) is a pivotal enzyme in the most prominent biosynth
Externí odkaz:
https://doaj.org/article/d836d5dfbaf740808ada4988984968f9
Publikováno v:
Frontiers in Veterinary Science, Vol 5 (2018)
Bovine tuberculosis (bTB) is an infectious, zoonotic disease caused by Mycobacterium bovis that can spread between domestic and wild animals, as well as to humans. The disease is characterized by the progressive development of lesions that compromise
Externí odkaz:
https://doaj.org/article/24353890a69047cc9184324abc389bf9
Autor:
Pedro Migliano, Laura S. Kabiri, Megan Cross, Allison Butcher, Amy Frugé, Wayne Brewer, Alexis Ortiz
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 4, Iss 3, Pp 44-0 (2019)
Cardiorespiratory fitness (CRF) is an important indicator of adolescent cardiovascular well-being and future cardiometabolic health but not always feasible to measure. The purpose of this study was to estimate the concurrent validity of the non-exerc
Externí odkaz:
https://doaj.org/article/9cec5fdd8d1849d4b42a328e71d556b5
Autor:
Shira Archie, Michael Almassey, Ashley Salzman, Alyssa Virola-Iarussi, Alysia D. Vrailas-Mortimer, Megan Cross, Devin Compton, Sarah M. Ryan, Nathan T. Mortimer, Lauren Naeger, Scott A. Barbee, Subhabrata Sanyal, David Myers, Julia M. Martin, Gia H. Ngo, Amelia M. Burch
Publikováno v:
Aging Cell
As organisms age, they often accumulate protein aggregates that are thought to be toxic, potentially leading to age‐related diseases. This accumulation of protein aggregates is partially attributed to a failure to maintain protein homeostasis. A va
Autor:
Megan Cross, Andreas Hofmann, Malte A. Karow, Jan Hendrik Straub, Christoph S. Clemen, Ludwig Eichinger
Publikováno v:
Biochemistry and Molecular Biology Education. 47:207-210
The Java software jBar consists of a graphical user interface that allows the user to customize and assemble an included script for R. The scripted R pipeline calculates means and standard errors/deviations for replicates of numerical bivariate data
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 17
Issue 23
QJM: An International Journal of Medicine
International Journal of Environmental Research and Public Health, Vol 17, Iss 8725, p 8725 (2020)
Volume 17
Issue 23
QJM: An International Journal of Medicine
International Journal of Environmental Research and Public Health, Vol 17, Iss 8725, p 8725 (2020)
International governments&rsquo
COVID-19 responses must balance human and economic health. Beyond slowing viral transmission, strict lockdowns have severe economic consequences. This work investigated response stringency, quantified by the Oxfor
COVID-19 responses must balance human and economic health. Beyond slowing viral transmission, strict lockdowns have severe economic consequences. This work investigated response stringency, quantified by the Oxfor
Autor:
Siji Rajan, Sonja Biberacher, Robin B. Gasser, Andreas Hofmann, Suk-Youl Park, Megan Cross, Mark J. Coster, Jeong-Sun Kim, Pasi K. Korhonen
Publikováno v:
The FASEB Journal. 32:5470-5482
The opportunistic bacterium Pseudomonas aeruginosa has been recognized as an important pathogen of clinical relevance and is a leading cause of hospital-acquired infections. The presence of a glycolytic enzyme in Pseudomonas, which is known to be inh
Autor:
Sonja Biberacher, Robin B. Gasser, Jeong-Sun Kim, Hmp Dilrukshi Herath, Ewa Długosz, Mark York, Andreas Hofmann, Megan Cross, John H. Ryan, Jan Hendrik Straub, Stephanie A. Logan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Protein-based drug discovery strategies have the distinct advantage of providing insights into the molecular mechanisms of chemical effectors. Currently, there are no known trehalose-6-phosphate phosphatase (TPP) inhibitors that possess reasonable in