Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Megan Calos"'
Publikováno v:
Neurobiology of Disease, Vol 52, Iss , Pp 128-136 (2013)
Seizures occur in the basal ganglia (BG) of epileptic patients and in animal models of epilepsy, but there is relatively little known about how these events are gated and/or propagated through this structure. Here, we present and characterize a model
Externí odkaz:
https://doaj.org/article/f4b0df7544814412804e489fd5b4b9f4
Autor:
Ian Walling, Jonathan M. Brotchie, Wilson Yu, Sujoy Phookan, Megan Calos, Autumn B. Smith, Alexander C Sutton, Katherine A. O'Connor, Julie G. Pilitsis, Joannalee C. Campbell, Damian S. Shin
Publikováno v:
Experimental Neurology. 265:160-170
Parkinson's disease (PD) is a neurodegenerative disease characterized by akinesia, bradykinesia, resting tremors and postural instability. Although various models have been developed to explain basal ganglia (BG) pathophysiology in PD, the recent rep
Publikováno v:
Neurobiology of Disease, Vol 52, Iss, Pp 128-136 (2013)
Seizures occur in the basal ganglia (BG) of epileptic patients and in animal models of epilepsy, but there is relatively little known about how these events are gated and/or propagated through this structure. Here, we present and characterize a model
Autor:
Wilson Yu, Julie G. Pilitsis, Jonathan M. Brotchie, Eric Molho, Adolfo Ramirez-Zamora, Alexander C Sutton, Autumn B. Smith, Megan Calos, Damian S. Shin
Publikováno v:
Journal of Neurophysiology. 109:363-374
Deep brain stimulation (DBS) employing high-frequency stimulation (HFS) is commonly used in the globus pallidus interna (GPi) and the subthalamic nucleus (STN) for treating motor symptoms of patients with Parkinson's disease (PD). Although DBS improv
Publikováno v:
Epilepsia. 52:2084-2093
SUMMARY Purpose: We investigated whether RS-isovaline, a unique amino acid found in carbonaceous meteorites and presumed extraterrestrial, has anticonvulsant properties in rat hippocampal slices in vitro. Methods: Extracellular recordings were obtain
Autor:
Lauren E. Mueller, Eric Molho, Matthew A. Berk, Damian S. Shin, Peter L. Carlen, Jonathan M. Brotchie, Megan Calos, Jenny Shim, Alexander C Sutton, Wilson Yu
Publikováno v:
The European journal of neuroscience. 37(2)
The mechanism of high-frequency stimulation used in deep brain stimulation (DBS) for Parkinson's disease (PD) has not been completely elucidated. Previously, high-frequency stimulation of the rat entopeduncular nucleus, a basal ganglia output nucleus
Publikováno v:
Journal of neurophysiology. 105(3)
Previously, we found that rat hippocampal CA3 interneurons become hyperactive with increasing concentrations of extracellular K+ up to 10 mM. However, it is unclear how this enhanced interneuronal activity affects pyramidal neurons. Here we voltage-c