Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Megan C. Mears"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Newcastle disease (ND), an economically important disease in poultry, is caused by virulent strains of the genetically diverse Orthoavulavirus javaense (OAVJ). Laboratories rely on quantitative real-time reverse transcription PCR (qRT-PCR) t
Externí odkaz:
https://doaj.org/article/83b5304af4a8447498ee1763fa8304ea
Autor:
Megan C. Mears, Abhijeet Bakre
Publikováno v:
Viruses, Vol 16, Iss 11, p 1748 (2024)
Post-transcriptional gene regulation mediated by microRNAs (miRNAs) relies on sequence complementarity between the miRNA seed site and the target gene transcript(s). This complementarity can completely inhibit or reduce translation into protein. We h
Externí odkaz:
https://doaj.org/article/0a96a6c917fd4665b3683ccc90242919
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic disease in humans. There is a great need for effective vaccines and therapeutics against CCHFV for humans, as none are currently international
Externí odkaz:
https://doaj.org/article/764f01de94e7466ea07a9706c4bdfb7c
Autor:
Sirri Kar, Sergio E. Rodriguez, Gurkan Akyildiz, Maria N. B. Cajimat, Rifat Bircan, Megan C. Mears, Dennis A. Bente, Aysen G. Keles
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Recent reports have demonstrated the presence of Crimean-Congo hemorrhagic fever virus (CCHFV) genomic material in Hyalomma aegyptium ticks feeding primarily on tortoises belonging to the genus Testudo. This raises the question if
Externí odkaz:
https://doaj.org/article/6c764a6c035e4dc78bda0da51686ca2a
Autor:
Megan C. Mears, Dennis A. Bente
Publikováno v:
Zoonoses, Vol 2, Iss 1, p 966 (2022)
No licensed vaccine is available to prevent the severe tick-borne disease Crimean-Congo hemorrhagic fever (CCHF), caused by the CCHF virus (CCHFV). This study sought to show that a combination of computational methods and data from published literatu
Externí odkaz:
https://doaj.org/article/83cda0551ef64379ba6eb5cd81d89a5d
Autor:
Victor K. Outlaw, Francesca T. Bovier, Megan C. Mears, Maria N. Cajimat, Yun Zhu, Michelle J. Lin, Amin Addetia, Nicole A. P. Lieberman, Vikas Peddu, Xuping Xie, Pei-Yong Shi, Alexander L. Greninger, Samuel H. Gellman, Dennis A. Bente, Anne Moscona, Matteo Porotto
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT The emergence of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the etiological agent of the 2019 coronavirus disease (COVID-19), has erupted into a global pandemic that has led to tens of millions of infections and hundr
Externí odkaz:
https://doaj.org/article/67347a10ef8144ada066a6a8fb7f2582
Autor:
Megan C. Mears, Sergio E. Rodriguez, Katharina S. Schmitz, Angel Padilla, Sudipta Biswas, Maria N.B. Cajimat, Chad E. Mire, Stephen R. Welch, Éric Bergeron, Christopher A. Alabi, Matteo Porotto, Dennis A. Bente
Publikováno v:
Antiviral Research, 207:105401. Elsevier
Crimean-Congo hemorrhagic fever (CCHF) is a medically relevant tick-borne viral disease caused by the Bunyavirus, Crimean-Congo hemorrhagic fever virus (CCHFV). CCHFV is endemic to Asia, the Middle East, South-eastern Europe, and Africa and is transm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d766dd6eb59f23980458f9b8a29576
https://pure.eur.nl/en/publications/5616b9c6-f826-4838-9d19-f476ffe4fa9f
https://pure.eur.nl/en/publications/5616b9c6-f826-4838-9d19-f476ffe4fa9f
Autor:
Megan C. Mears, Aysen Gargili Keles, Gurkan Akyildiz, Maria N.B. Cajimat, Sırrı Kar, Rifat Bircan, Sergio E. Rodriguez, Dennis A. Bente
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-13 (2020)
Parasites & Vectors
Parasites & Vectors
Background Recent reports have demonstrated the presence of Crimean-Congo hemorrhagic fever virus (CCHFV) genomic material in Hyalomma aegyptium ticks feeding primarily on tortoises belonging to the genus Testudo. This raises the question if these ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76342121954a43983f033b1276e280a1
http://link.springer.com/article/10.1186/s13071-020-04074-6
http://link.springer.com/article/10.1186/s13071-020-04074-6
Autor:
Pavitra Roychoudhury, Francesca T. Bovier, Anne Moscona, Alexander L. Greninger, Dennis A. Bente, Maria N.B. Cajimat, Nicole A P Lieberman, Pei Yong Shi, Lasata Shrestha, Keith R. Jerome, Megan C. Mears, Vikas Peddu, Matteo Porotto, Meei Li Huang, Hong Xie
Publikováno v:
PLoS Biology, Vol 18, Iss 9, p e3000849 (2020)
bioRxiv
PLoS Biology
bioRxiv
PLoS Biology
Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide range of clinical manifestations in different patient populations. The mechanisms behind these host differences are still unclear. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e588816447fb532ce779332c8990d0eb
https://doaj.org/article/daaebf39e64a4d86833f32bea472d70f
https://doaj.org/article/daaebf39e64a4d86833f32bea472d70f
Autor:
Keith R. Jerome, Megan C. Mears, Matteo Porotto, Pei Yong Shi, Nicole A P Lieberman, Alexander L. Greninger, Anne Moscona, Meei-Li Huang, Maria N.B. Cajimat, Lasata Shrestha, Hong Xie, Vikas Peddu, Pavitra Roychoudhury, Francesca T. Bovier, Dennis A. Bente
Despite limited genomic diversity, SARS-CoV-2 has shown a wide range of clinical manifestations in different patient populations. The mechanisms behind these host differences are still unclear. Here, we examined host response gene expression across i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2cadefd4bd42f65fb7bb071d6f372bc
https://doi.org/10.1101/2020.06.22.165225
https://doi.org/10.1101/2020.06.22.165225