Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Megan C. Hofmann"'
Autor:
Sridevi Nagaraja, Luis F. Queme, Megan C. Hofmann, Shivendra G. Tewari, Michael P. Jankowski, Jaques Reifman
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Nociceptive nerve endings embedded in muscle tissue transduce peripheral noxious stimuli into an electrical signal [i.e., an action potential (AP)] to initiate pain sensations. A major contributor to nociception from the muscles is mechanosensation.
Externí odkaz:
https://doaj.org/article/a14c0fada30744a68434c06eb308f1cc
Autor:
Namrata G.R. Raut, Laura A. Maile, Leila M. Oswalt, Irati Mitxelena, Aaditya Adlakha, Kourtney L. Sprague, Ashley R. Rupert, Lane Bokros, Megan C. Hofmann, Jennifer Patritti-Cram, Tilat A. Rizvi, Luis F. Queme, Kwangmin Choi, Nancy Ratner, Michael P. Jankowski
SummaryPain of unknown etiology is frequent in individuals with the tumor predisposition syndrome Neurofibromatosis 1 (NF1), even when tumors are absent. Schwann cells (SC) were recently shown to play roles in nociceptive processing, and we find that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbff1a05aa1b73e322bcc5e956bd6d99
https://doi.org/10.1101/2023.03.18.533004
https://doi.org/10.1101/2023.03.18.533004
Autor:
Adam J. Dourson, Adewale O. Fadaka, Anna M. Warshak, Aditi Paranjpe, Benjamin Weinhaus, Luis F. Queme, Megan C. Hofmann, Heather M. Evans, Omer A. Donmez, Carmy Forney, Matthew T. Weirauch, Leah C. Kottyan, Daniel Lucas, George S. Deepe, Michael P. Jankowski
Publikováno v:
bioRxiv
The developing peripheral nervous and immune systems are functionally distinct from adults. These systems are vulnerable to effects of early life injury which can influence outcomes related to nociception following subsequent injury later in life (i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a7fbc1c42467b36a36b62498dcd6c8
https://doi.org/10.1101/2023.02.13.528015
https://doi.org/10.1101/2023.02.13.528015
Autor:
Luis F Queme, Adam Dourson, Megan C Hofmann, Ally Butterfield, Rudolph D. Paladini, Michael P Jankowski
Publikováno v:
eNeuro. 9(2)
PEGPH20, a human recombinant hyaluronidase, has been proposed as a coadjutant to pancreatic cancer chemotherapy. In early trials, patients reported increased widespread muscle pain as the main adverse reaction to PEGPH20. To understand how PEGPH20 ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cbde8adfa56d68bc70449a9a792365
https://pubmed.ncbi.nlm.nih.gov/35387844
https://pubmed.ncbi.nlm.nih.gov/35387844
Publikováno v:
The Journal of Pain. 23:9-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b3995dacee06ec69c23edefdd69df97
https://doi.org/10.1016/j.jpain.2022.03.036
https://doi.org/10.1016/j.jpain.2022.03.036
Publikováno v:
The Journal of Pain. 23:1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b1a91214ec86a08391951607ff18ae
https://doi.org/10.1016/j.jpain.2022.03.006
https://doi.org/10.1016/j.jpain.2022.03.006
Publikováno v:
The Journal of Pain. 22:578
Young children perceive nociceptive stimuli and experience pain differently than adults, but the underlying mechanisms that cause these differential effects are unknown. The result of this uncertainty can lead to incomplete pain management for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fcde08229c9a0308a3624b41b673c4a
https://doi.org/10.1016/j.jpain.2021.03.003
https://doi.org/10.1016/j.jpain.2021.03.003
Autor:
Xiaohua Liu, Megan C. Hofmann, Luis F. Queme, Peilin Lu, Zachary K. Ford, Renita C. Hudgins, Michael P. Jankowski
Publikováno v:
Molecular Pain
The upregulation of various channels and receptors classically linked to sensory transduction from the periphery tightly correspond with changes in the responsiveness of specific subpopulations of primary afferents to mechanical and heat stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d463292d801d4f01163da398d96fd7b7
https://doi.org/10.1177/1744806917730255
https://doi.org/10.1177/1744806917730255