Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Megan C Kopp"'
Publikováno v:
eLife, Vol 7 (2018)
The unfolded protein response (UPR) is a key signaling system that regulates protein homeostasis within the endoplasmic reticulum (ER). The primary step in UPR activation is the detection of misfolded proteins, the mechanism of which is unclear. We h
Externí odkaz:
https://doaj.org/article/88b0d67bad444a3e84ee50a3e8e7b2fa
Publikováno v:
eLife, Vol 4 (2015)
The unfolded protein response (UPR) is an essential cell signaling system that detects the accumulation of misfolded proteins within the endoplasmic reticulum (ER) and initiates a cellular response in order to maintain homeostasis. How cells detect t
Externí odkaz:
https://doaj.org/article/5e74516079db4a84b1f56ab203f5f8ee
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
The endoplasmic reticulum (ER) is an important site for protein folding and maturation in eukaryotes. The cellular requirement to synthesize proteins within the ER is matched by its folding capacity. However, the physiological demands or aberrations
Externí odkaz:
https://doaj.org/article/d27d807958cf4c4d93c2aa5d7a0255af
Publikováno v:
Nature structural & molecular biology
BiP is a major endoplasmic reticulum (ER) chaperone and is suggested to act as primary sensor in the activation of the unfolded protein response (UPR). How BiP operates as a molecular chaperone and as an ER stress sensor is unknown. Here, by reconsti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792c8985ad16f0004856efbc71f7420f
http://hdl.handle.net/10044/1/74374
http://hdl.handle.net/10044/1/74374
Publikováno v:
Frontiers in Molecular Biosciences
The endoplasmic reticulum (ER) is an important site for protein folding and maturation in eukaryotes. The cellular requirement to synthesize proteins within the ER is matched by its folding capacity. However, the physiological demands or aberrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f85b794dd65b05af58d527338d0945a0
https://pubmed.ncbi.nlm.nih.gov/30931312
https://pubmed.ncbi.nlm.nih.gov/30931312
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
The unfolded protein response (UPR) is a key signaling system that regulates protein homeostasis within the endoplasmic reticulum (ER). The primary step in UPR activation is the detection of misfolded proteins, the mechanism of which is unclear. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5cf4657413c1b68f25f1dba3a7db26
http://hdl.handle.net/10044/1/55696
http://hdl.handle.net/10044/1/55696
Autor:
Wei Feng Zhen, Tyler J. Gerwig, Mark J. Snider, Katherine A. Hicks, Meigan E. Yuen, Ryan W. Story, Megan C. Kopp
Publikováno v:
Biochemistry. 55(24)
The genes coding for the enzymes of oxidative degradation of nicotinic acid have recently been identified in several species of aerobic bacteria, namely, Pseudomonas putida KT2440, Bordetella bronchiseptica RB50, and Bacillus niacini. One of the enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6da1e9bfa31a1f171962585f0951c5d
https://pubmed.ncbi.nlm.nih.gov/27218267
https://pubmed.ncbi.nlm.nih.gov/27218267