Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Megan Burley"'
Autor:
Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson, Philip J. Byrd, Megan Burley, Archana Sharma-Oates, Peter Keane, Sael Alatawi, Martin R. Higgs, Zbigniew Rudzki, Maha Ibrahim, Tracey Perry, Angelo Agathaggelou, Anne-Marie Hewitt, Edward Smith, Constanze Bonifer, Mark O’Connor, Josep V. Forment, Paul G. Murray, Eanna Fennell, Gemma Kelly, Catherine Chang, Grant S. Stewart, Tatjana Stankovic, Marwan Kwok, Alexander Malcolm Taylor
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Diffuse large B-cell lymphoma (DLBCL) is the most common malignancy that develops in patients with ataxia-telangiectasia, a cancer-predisposing inherited syndrome characterized by inactivating germline ATM mutations. ATM is also frequently mutated in
Externí odkaz:
https://doaj.org/article/a850f4208cec4de88e6a8aaa3e6fc37b
Publikováno v:
Viruses, Vol 16, Iss 5, p 670 (2024)
The HIV-1 capsid (CA) protein forms the outer shell of the viral core that is released into the cytoplasm upon infection. CA binds various cellular proteins, including CPSF6, that direct HIV-1 integration into speckle-associated domains in host chrom
Externí odkaz:
https://doaj.org/article/69d769fb149f493cb94850e23de2fbc8
Autor:
Ieisha Pentland, Karen Campos-León, Marius Cotic, Kelli-Jo Davies, C David Wood, Ian J Groves, Megan Burley, Nicholas Coleman, Joanne D Stockton, Boris Noyvert, Andrew D Beggs, Michelle J West, Sally Roberts, Joanna L Parish
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e2005752 (2018)
The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted. Upon epithelial differentiation, E6/E7 transcription is increased t
Externí odkaz:
https://doaj.org/article/2b634e44faf441ed83f18dab7b93bedd
Autor:
Hannah J. Gleneadie, Alfredo A. Molinolo, Deena M.A. Gendoo, Yao Jiang, Amy H. Baker, Jennifer L. Bryant, Sally Roberts, Paloma Garcia, Megan Burley, Joanna L Parish, J. Silvio Gutkind, Hisham Mehanna, Ben A. Scheven, Malgorzata Wiench, Nikolaos Batis, Farhat L. Khanim, Paul R. Cooper, Samuel J.H. Clokie
Publikováno v:
Cancer Letters
The DNA demethylating agent 5-aza-2′-deoxycytidine (DAC, decitabine) has anti-cancer therapeutic potential, but its clinical efficacy is hindered by DNA damage-related side effects and its use in solid tumours is debated. Here we describe how parac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe4cd8568248d99b4bf1ab3a36cfd2a
https://doi.org/10.1016/j.canlet.2020.12.029
https://doi.org/10.1016/j.canlet.2020.12.029
Publikováno v:
Seminars in Immunopathology
Human papillomaviruses (HPV) are a large family of viruses which contain a circular, double-stranded DNA genome of approximately 8000 base pairs. The viral DNA is chromatinized by the recruitment of cellular histones which are subject to host cell–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3964666163c50fe5654170313acefa0
https://doi.org/10.1007/s00281-019-00773-0
https://doi.org/10.1007/s00281-019-00773-0