Cytokine Profiles of Severe Influenza Virus-Related Complications in Children

Autor: Andrew Fiore-Gartland, Angela Panoskaltsis-Mortari, Anna A. Agan, Anushay J. Mistry, Paul G. Thomas, Michael A. Matthay, PALISI PICFlu Investigators, Tomer Hertz, Adrienne G. Randolph, Ronald C. Sanders, Glenda Hefley, David Tellez, Courtney Bliss, Aimee Labell, Danielle Liss, Ashley L. Ortiz, Katri Typpo, Jen Deschenes, Barry Markovitz, Jeff Terry, Rica Sharon P. Morzov, Ana Lia Graciano, Melita Baldwin, Nick Anas, Adam Schwarz, Chisom Onwunyi, Stephanie Osborne, Tiffany Patterson, Ofelia Vargas-Shiraishi, Anil Sapru, Maureen Convery, Victoria Lo, Heidi Flori, Becky Brumfield, Julie Simon, Angela Czaja, Peter Mourani, Valeri Batara Aymami, Susanna Burr, Megan Brocato, Stephanie Huston, Emily Jewett, Danielle Loyola, Christopher Carroll, Kathleen Sala, Sherell Thornton-Thompson, John S. Giuliano, Joana Tala, Gwenn McLaughlin, Matthew Paden, Chee-Chee Manghram, Stephanie Meisner, Cheryl L. Stone, Juliane Bubeck Wardenburg, Andrea DeDent, Vicki Montgomery, Janice Sullivan, Tracy Evans, Kara Richardson, Melissa Thomas, Adrienne Randolph, Ryan M. Sullivan, Stephanie Cobb, Melania Bembea, Elizabeth D. White, Stephen Kurachek, Angela A. Doucette, Erin Olson, Mary Hartman, Rachel Jacobs, Edward Truemper, Machelle Dawson, Daniel L. Levin, J. Dean Jarvis, Chhavi Katyal, Kate Ackerman, L. Eugene Daugherty, Laurel Baglia, Mark W. Hall, Kristin Greathouse, Lisa Steele, Neal Thomas, Jill Raymond, Debra Spear, Julie Fitzgerald, Mark Helfaer, Scott Weiss, Jenny L. Bush, Mary Ann Diliberto, Brooke B. Park, Martha Sisko, Frederick E. Barr, Renee Higgerson, LeeAnn Christie, Cindy Darnell, Shanda Johnson, Laura L. Loftis, Nancy Jaimon, Ursula Kyle, Rainer Gedeit, Briana E. Horn, Kate Luther, Kathy Murkowski, Douglas F. Willson, Robin L. Kelly, Philippe A. Jouvet, Anne-Marie Fontaine, Marc-André Dugas

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

RationaleEffective immunomodulatory therapies for children with life-threatening “cytokine storm” triggered by acute influenza infection are lacking. Understanding the immune profiles of children progressing to severe lung injury and/or septic sh

Externí odkaz: https://doaj.org/article/9925da23ab434b12b96add0712f9d0e8

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection

Autor: Lisa N. Steele, Natalie Z. Cvijanovich, David Finkelstein, J. Dean Jarvis, Vicki L. Montgomery, Brooke B. Park, Matthew L. Paden, Chee-Chee Manghram, Judi Arnold, Yu Zhang, Juliane Bubeck Wardenburg, Anna A. Agan, Kristin Greathouse, Marc-André Dugas, Ronald C. Sanders, Stephanie Osborne, Eloise Lemon, E.K. Allen, Rachel Jacobs, Angela Czaja, Katri Typpo, Sherell Thornton-Thompson, L. Eugene Daugherty, Philippe Jouvet, Stephanie Meisner, Angela A. Doucette, Kara Richardson, Sandra B. Lindahl, Jillian Egan, Melania Bembea, Laurel Baglia, Mary E. Hartman, Scott L. Weiss, Healther Anthony, Megan Brocato, Tracy Evans, Aimee Labell, Michael Kiers, Carrie M. Rosenberger, Susanna Burr, Stephanie Huston, Adam Schwarz, Frederick E. Barr, Cheryl L. Stone, Mary Ann Diliberto, Nancy Jaimon, Ashely L. Ortiz, Jenny L. Bush, Maureen Convery, Mark W. Hall, Monroe Carell, Chisom Onwunyi, Courtney Bliss, Shivan Shetty, Ramon Adams, Anne-Marie Fontaine, Ana Lia Graciano, Machelle Dawson, Neal J. Thomas, Danielle Liss, Peter M. Mourani, Marita Thompson, Martha Sisko, Anil Sapru, Barry P. Markovitz, Tiffany Patterson, Kate Luther, Victoria Lo, Grace Yoon, Stephanie A. Ash, Tushar Bhangale, Robin L. Kelly, Elizabeth D. White, Erin Zielinski, Renee A. Higgerson, Glenda Hefley, Jen Deschenes, Kate G. Ackerman, Chhavi Katyal, Mark A. Helfaer, Ryan Nofziger, Melita Baldwin, LeeAnn M. Christie, Paul G. Thomas, John S. Giuliano, Briana E. Horn, Stephen C. Kurachek, Douglas F. Willson, Ryan M. Sullivan, Kate Sewell, Edward J. Truemper, Julie C. Fitzgerald, Jill Raymond, Avani Shukla, Valeri Batara Aymami, Gwenn E. McLaughlin, Julie Simon, Helen C. Su, Kathleen A. Sala, Christopher L. Carroll, Ursula Kyle, Heidi R. Flori, Shannon M. Keisling, Rainer Gedeit, Debra Spear, Andrea C. DeDent, Joana Tala, Rich Toney, Kathy Murkowski, Ellen M. Smith, Yamila Sierra, Nick Anas, Bria M. Coates, Emily Jewett, Peter Mourani, Christine Traul, Adrienne G. Randolph, Allan Doctor, Jeff Terry, Lisa Petersen, Daniel L. Levin, Danielle Loyola, David Tellez, Michele Kong, Steve Shein, Becky Brumfield, Rica Sharon P. Morzov, Laura Loftis, Wai-Ki Yip, Susan Bergant, Ofelia Vargas-Shiraishi

Publikováno v: The Journal of infectious diseases. 216(1)

Background Interferon-induced transmembrane protein 3 (IFITM3) restricts endocytic fusion of influenza virus. IFITM3 rs12252_C, a putative alternate splice site, has been associated with influenza severity in adults. IFITM3 has not been evaluated in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25f1471a3bce96acb7a4b966f426f55
https://pubmed.ncbi.nlm.nih.gov/28531322

Innate immune function in placenta and cord blood of hepatitis C--seropositive mother-infant dyads

Autor: Hugo R. Rosen, Michael R. Narkewicz, Megan Brocato, Mona Krull, Christine Waasdorp Hurtado, Lucy Golden-Mason

Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12232 (2010)
PLoS ONE

Vertical transmission accounts for the majority of pediatric cases of hepatitis C viral (HCV) infection. In contrast to the adult population who develop persistent viremia in approximately 80% of cases following exposure, the rate of mother-to-child

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627a31ff7367fa05fd19692544d86e97
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20814429/?tool=EBI