Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Megan Altemus"'
Autor:
Trisha M. Westerhof, Benjamin A. Yang, Nathan M. Merrill, Joel A. Yates, Megan Altemus, Liam Russell, Anna J. Miller, Liwei Bao, Zhifen Wu, Peter J. Ulintz, Carlos A. Aguilar, Aki Morikawa, Maria G. Castro, Sofia D. Merajver, Christopher R. Oliver
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 8, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/87947428f0654eeab189f5ee0a14f82f
Autor:
Sachin Patel, Andrew D. Gaulden, Amanda J. Morgan, Samuel W. Centanni, Danny G. Winder, Megan Altemus, Kellie M. Williford
Publikováno v:
Brain Behav Immun
Stress is a major risk factor for the development and exacerbation of mood and anxiety disorders, and recent studies have suggested inflammatory contributions to the pathogenesis of depression. Interestingly, pharmacological inhibition of cyclooxygen
Autor:
Nathan D. Winters, Cody A. Siciliano, Samuel W. Centanni, Amanda J. Morgan, Snigdha Mukerjee, Philip J. Kingsley, Keenan D Johnson, Anastasia A Astafyev, Gaurav Bedse, Lawrence J. Marnett, Vikrant R. Mahajan, David C. Samuels, Jashim Uddin, Toni A. Patrick, Sachin Patel, Megan Altemus, Danny G. Winder
Publikováno v:
J Clin Invest
Alcohol use disorder (AUD) is associated with substantial morbidity, mortality, and societal cost, and pharmacological treatment options are limited. The endogenous cannabinoid (eCB) signaling system is critically involved in reward processing, and a
Autor:
Ken Mackie, Nathan D. Winters, James D. Ryan, Eric Delpire, Sachin Patel, Megan Altemus, David J. Marcus, Gaurav Bedse, Andrew D. Gaulden, Luis Eduardo Rosas-Vidal, Francis S. Lee, Veronika Kondev
Publikováno v:
Neuron
Functional coupling between the amygdala and the dorsomedial prefrontal cortex (dmPFC) has been implicated in the generation of negative affective states; however, the mechanisms by which stress increases amygdala-dmPFC synaptic strength and generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa2a84a51a6160bbc861aebc6e80349
https://europepmc.org/articles/PMC7992313/
https://europepmc.org/articles/PMC7992313/
Autor:
Carrie A. Grueter, Maya P. Misra, Rita Báldi, Nolan D. Hartley, Brad A. Grueter, Oakleigh M. Folkes, Sachin Patel, Megan Altemus, David J. Marcus, Brandon D. Turner, Jordan J. Baechle, Veronika Kondev, Jade K. Ayers
Publikováno v:
J Clin Invest
Deficits in social interaction (SI) are a core symptom of autism spectrum disorders (ASDs); however, treatments for social deficits are notably lacking. Elucidating brain circuits and neuromodulatory signaling systems that regulate sociability could
Autor:
Xu Cheng, Megan Altemus, Jason Heth, Sofia D. Merajver, Trisha M. Westerhof, Aki Morikawa, Maria G. Castro, Zhifen Wu, C. Ryan Oliver, Michelle Dziubinski, Shuichi Takayama, Joel A. Yates, Brendan M. Leung, Hannah Cheriyan
Publikováno v:
Lab on a chip. 19(7)
Brain metastases are the most lethal complication of advanced cancer; therefore, it is critical to identify when a tumor has the potential to metastasize to the brain. There are currently no interventions that shed light on the potential of primary t
Autor:
Sachin Patel, Michelle M. Mitchener, Megan Altemus, Amanda J. Morgan, Andrew D. Gaulden, Lawrence J. Marnett, Philip J. Kingsley, Toni A. Patrick
Cyclooxygenase-2 (COX-2) catalyzes the formation of prostaglandins, which are involved in immune regulation, vascular function, and synaptic signaling. COX-2 also inactivates the endogenous cannabinoid (eCB) 2-arachidonoylglycerol (2-AG) via oxygenat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605f039d34ceea275e11bd981296c5c9
https://europepmc.org/articles/PMC6081739/
https://europepmc.org/articles/PMC6081739/
Autor:
Liwei Bao, Megan White, Megan Altemus, Xinyu Tan, Julia Prisby, Joel A. Swanson, Zhifen Wu, Allen P. Liu, Kenneth K. Y. Ho, Sei Yoshida, Sofia D. Merajver, Joel A. Yates, Sarah L. Veatch, Luciana K. Rosselli-Murai, Julia T. Bourg
Defective endocytosis and vesicular trafficking of signaling receptors has recently emerged as a multifaceted hallmark of malignant cells. Clathrin-coated pits (CCPs), the fundamental unit of clathrin-mediated endocytosis, display highly heterogeneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8964d5a07b23a766f6c12c0b20497f21
https://doi.org/10.1101/137760
https://doi.org/10.1101/137760
Autor:
Sofia D. Merajver, Joel A. Yates, Megan Altemus, Zhi Fen Wu, Laura E. Goo, Hannah Cheriyan, Andrew C. Little
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0220973 (2019)
PLoS ONE
PLoS ONE
In breast cancer, tumor hypoxia has been linked to poor prognosis and increased metastasis. Hypoxia activates transcriptional programs in cancer cells that lead to increased motility and invasion, as well as various metabolic changes. One of these me
Autor:
Zhi Fen Wu, Steven G. Allen, Chelsea Fournier, Joel A. Yates, Ayse B. Hiziroglu, Euisik Yoon, Yu Chih Chen, Liwei Bao, Megan Altemus, Sofia D. Merajver, Julie M. Madden, Yu Heng Cheng
Publikováno v:
Scientific Reports
Inflammatory breast cancer (IBC) is the most lethal form of breast cancer. All IBC patients have lymph node involvement and one-third of patients already have distant metastasis at diagnosis. This propensity for metastasis is a hallmark of IBC distin