Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Megan A. Jamiolkowski"'
Autor:
Mehulkumar Patel, Megan A. Jamiolkowski, Anjali Vejendla, Viviana Bentley, Richard A. Malinauskas, Qijin Lu
Publikováno v:
ASAIO Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8013ab8dc0c052cd13db5379a8d099
https://doi.org/10.1097/mat.0000000000001897
https://doi.org/10.1097/mat.0000000000001897
Autor:
Megan A. Jamiolkowski, Mehulkumar Patel, Madelyn D. Golding, Richard A. Malinauskas, Qijin Lu
Publikováno v:
Artificial organs. 46(12)
To determine suitable alternatives to human blood for in vitro dynamic thrombogenicity testing of biomaterials, four different animal blood sources (ovine, bovine, and porcine blood from live donors, and abattoir porcine blood) were compared to fresh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9e023cbf5c292ba8d65385759b4689
https://pubmed.ncbi.nlm.nih.gov/35866431
https://pubmed.ncbi.nlm.nih.gov/35866431
Publikováno v:
ASAIO Journal. 67:214-219
Device-related thrombosis and thromboembolic complications remain a major clinical concern and often impact patient morbidity and mortality. Thus, improved preclinical thrombogenicity assessment methods that better predict clinical outcomes and enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ad5790920f356d6378d6620baaf2f5
https://doi.org/10.1097/mat.0000000000001226
https://doi.org/10.1097/mat.0000000000001226
Publikováno v:
ASAIO Journal. 66:183-189
A reliable in vitro dynamic test method to evaluate device thrombogenicity is very important for the improvement of the design and safety of blood-contacting medical devices, while reducing the use of animal studies. In this study, a recirculating fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f2f8918484f151fcb5a1e8a9ea73a2
https://doi.org/10.1097/mat.0000000000000958
https://doi.org/10.1097/mat.0000000000000958
Autor:
Qijin Lu, Megan A Jamiolkowski, Richard A. Malinauskas, Jean E. Rinaldi, Joshua M Nehrer, Jiaming Li
Publikováno v:
J Biomed Mater Res B Appl Biomater
An appropriate preclinical thrombogenicity evaluation of a blood-contacting device is important to reduce thrombosis and thromboembolism risks to patients. The in vitro platelet and leukocyte count assay, as described in the ASTM F2888 test standard,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900de82c649723514b7d2c423a5a6ac8
https://europepmc.org/articles/PMC8490275/
https://europepmc.org/articles/PMC8490275/
Autor:
Megan A Jamiolkowski, Brent A. Craven, Gavin A. D'Souza, Luke H. Herbertson, Oleg Vesnovsky, Ksenia Blinova, Matthew Di Prima, Qijin Lu, Masoud Farahmand, Richard A. Malinauskas, Mehulkumar Patel, Nandini Duraiswamy, Kenneth I. Aycock, Prasanna Hariharan, Jason D. Weaver, Jean E. Rinaldi, Maura Casciola, Shiril Sivan
Publikováno v:
2021 Design of Medical Devices Conference.
The Cardiovascular Research Program in OSEL at the FDA consists of a diverse group of engineers and scientists who seek to drive innovation in cardiovascular device technology through development and standardization of pre-clinical test methods using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b27d72f571387b452bec0c92a813cfa
https://doi.org/10.1115/dmd2021-1085
https://doi.org/10.1115/dmd2021-1085
Publikováno v:
ASAIO Journal. 68:99-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a991415865ce3ff2f118c1b8e17868
https://doi.org/10.1097/01.mat.0000841280.30962.f0
https://doi.org/10.1097/01.mat.0000841280.30962.f0
Publikováno v:
J Biomech
Thromboembolic complications remain a central issue in management of patients on mechanical circulatory support. Despite the best practices employed in design and manufacturing of modern ventricular assist devices, complexity and modular nature of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac69474e18c3a527930c27de27ced988
http://arxiv.org/abs/2011.10560
http://arxiv.org/abs/2011.10560
Publikováno v:
Biomaterials. 96:72-83
The blood flow pathway within a device, together with the biomaterial surfaces and status of the patient’s blood, are well-recognized factors in the development of thrombotic deposition and subsequent embolization. Blood flow patterns are of partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afb6f912cb12420b1f865fbaf97c760
https://doi.org/10.1016/j.biomaterials.2016.04.022
https://doi.org/10.1016/j.biomaterials.2016.04.022
Autor:
James F. Antaki, Nadine Aubry, Wei-Tao Wu, Mehrdad Massoudi, William R. Wagner, Megan A. Jamiolkowski
Publikováno v:
Scientific Reports
In this paper, we present a spatio-temporal mathematical model for simulating the formation and growth of a thrombus. Blood is treated as a multi-constituent mixture comprised of a linear fluid phase and a thrombus (solid) phase. The transport and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b3e77143da38800b0a9a476d7e1082
https://doi.org/10.1038/srep42720
https://doi.org/10.1038/srep42720