Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Megan A Sheridan"'
1
Akademický článek
African and Asian strains of Zika virus differ in their ability to infect and lyse primitive human placental trophoblast.
Autor: Megan A Sheridan, Velmurugan Balaraman, Danny J Schust, Toshihiko Ezashi, R Michael Roberts, Alexander W E Franz
Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0200086 (2018)
Zika virus (ZIKV) drew worldwide attention when a recent epidemic was linked to fetal microcephaly. Here we used human embryonic stem cell derived trophoblasts as a model for primitive placental trophoblast to test the hypothesis that there are diffe
Externí odkaz: https://doaj.org/article/11424b9e876242bc8a08c9a17828b20c
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2
Akademický článek
The immune checkpoint molecule, VTCN1/B7-H4, guides differentiation and suppresses proinflammatory responses and MHC class I expression in an embryonic stem cell-derived model of human trophoblast
Autor: Jie Zhou, Yuchen Tian, Ying Qu, Madyson Williams, Ye Yuan, Rowan M. Karvas, Megan A. Sheridan, Laura C. Schulz, Toshihiko Ezashi, Michael R. Roberts, Danny J. Schust
Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)
The placenta acts as a protective barrier to pathogens and other harmful substances present in the maternal circulation throughout pregnancy. Disruption of placental development can lead to complications of pregnancy such as preeclampsia, intrauterin
Externí odkaz: https://doaj.org/article/ef4317e854f24c9fbdf2b85ad558ca16
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3
Akademický článek
Modeling the Human Placenta to Investigate Viral Infections During Pregnancy
Autor: Megan A. Sheridan, Jie Zhou, Alexander W. E. Franz, Danny J. Schust
Publikováno v: Frontiers in Virology, Vol 2 (2022)
Throughout gestation, the placenta is vital for proper development of the fetus. Disruptions in trophoblast, the main functional cell type of the placenta, stress the pregnancy, with potential adverse outcomes for both mother and baby. While the plac
Externí odkaz: https://doaj.org/article/5c49cd09b65049a5b8458d8c307d84a2
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6
Could the Human Endogenous Retrovirus-Derived Syncytialization Inhibitor, Suppressyn, Limit Heterotypic Cell Fusion Events in the Decidua?
Autor: Iemasa Koh, Megan A. Sheridan, Jun Sugimoto, Sehee Choi, Danny J. Schust, Yoshiki Kudo
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10259, p 10259 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19
Proper placental development relies on tightly regulated trophoblast differentiation and interaction with maternal cells. Human endogenous retroviruses (HERVs) play an integral role in modulating cell fusion events in the trophoblast cells of the dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae9f86a659cc43b7e6d072b88d8efe5
https://www.mdpi.com/1422-0067/22/19/10259
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7
Early onset preeclampsia in a model for human placental trophoblast
Autor: Mark R. Ellersieck, Penghua Yang, Aihua Dai, Ashish Jain, Laura C. Schulz, Ying Yang, Sambasiva R. Brahmasani, Yuchen Tian, Megan A. Sheridan, Danny J. Schust, Toshihiko Ezashi, Geetu Tuteja, Alex S. Lyons, R. Michael Roberts
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Significance Preeclampsia, a leading cause of maternal and perinatal morbidity and mortality worldwide, is accompanied by shallow placentation and deficient remodeling of the uterine spiral arteries by invasive placental trophoblast cells during the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c9e2e60bf3f7f92c5e50b936c1c983
https://doi.org/10.1073/pnas.1816150116
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8
Establishment and differentiation of long-term trophoblast organoid cultures from the human placenta
Autor: Ridma C. Fernando, Michael Hollinshead, Megan A. Sheridan, Lucy Gardner, Ashley Moffett, Graham J. Burton, Margherita Y. Turco
Publikováno v: nature protocols
The human placenta is essential for successful reproduction. There is great variation in the anatomy and development of the placenta in different species, meaning that animal models provide limited information about human placental development and fu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23deb424bde75b50b78b6ba4d49f8d2f
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9
The Kodály Concept in the United States: Early American Adaptations to Recent Evolutions
Autor: Megan M. Sheridan
Publikováno v: Journal of Historical Research in Music Education. 41:55-72
Zoltán Kodály, a Hungarian composer, ethnomusicologist, and music educator, is widely known for his philosophical and pedagogical contributions to music education. The purpose of this article was to trace the development of the Kodály movement in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5293bcf2145ec874b8a4277c9d375e18
https://doi.org/10.1177/1536600618787481
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10
Specification of trophoblast from embryonic stem cells exposed to BMP4†
Autor: Toshihiko Ezashi, R. Michael Roberts, Megan A. Sheridan, Ying Yang
Publikováno v: Biology of Reproduction. 99:212-224
Trophoblast (TB) comprises the outer cell layers of the mammalian placenta that make direct contact with the maternal uterus and, in species with a highly invasive placenta, maternal blood. It has its origin as trophectoderm, a single epithelial laye
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2d1fc18dfb9f618c982164eabdc41f
https://doi.org/10.1093/biolre/ioy070
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