Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Megan, Stevens"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The development of methodologies to analyse circulating tumour DNA (ctDNA) in the blood or urine of cancer patients provides an invaluable resource that can be used for diagnosis and prognosis and to evaluate response to treatments. Lung cancer has s
Externí odkaz:
https://doaj.org/article/1075d8d44f40445aa6c536534424b1f0
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 147-157 (2022)
Research in the area of hallmarks of cancer has opened the possibility of designing new therapies based on modulating these cancer properties. We present here a screen designed to find chemicals that modulate epithelial-mesenchymal transitions (EMTs)
Externí odkaz:
https://doaj.org/article/f5f8b4cf67cd45919c237149c708434a
Autor:
Eleanor Star, Megan Stevens, Clare Gooding, Christopher W. J. Smith, Ling Li, Monica Lamici Ayine, Steve J. Harper, David O. Bates, Sebastian Oltean
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-12 (2021)
Abstract Alternative splicing of the vascular endothelial growth factor A (VEGF-A) terminal exon generates two protein families with differing functions. Pro-angiogenic VEGF-Axxxa isoforms are produced via selection of the proximal 3′ splice site o
Externí odkaz:
https://doaj.org/article/b2b9f454833f4965855002d89dcada06
Autor:
Megan Stevens, Sebastian Oltean
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Apoptosis plays a vital role in cell homeostasis during development and disease. Bcl-x, a member of the Bcl-2 family of proteins, is a mitochondrial transmembrane protein that functions to regulate the intrinsic apoptosis pathway. An alternative spli
Externí odkaz:
https://doaj.org/article/31cd291a0a984840bbdf65b06bca925c
Autor:
Natalie C. Finch, Sarah S. Fawaz, Chris R. Neal, Matthew J. Butler, Vivian K. Lee, Andrew J. Salmon, Abigail C. Lay, Megan Stevens, Lusyan Dayalan, Hamid Band, Harry H. Mellor, Steven J. Harper, David T. Shima, Gavin I. Welsh, Rebecca R. Foster, Simon C. Satchell
Publikováno v:
University of Bristol-PURE
J Am Soc Nephrol
Finch, N C, Fawaz, S, Neal, C R, Butler, M J, Salmon, A, Lay, A C, Stevens, M, Mellor, H H, Harper, S J, Welsh, G I, Foster, R & Satchell, S C 2022, ' Reduced glomerular filtration in diabetes is attributable to loss of density and increased resistance of glomerular endothelial cell fenestrations ', Journal of the American Society of Nephrology, vol. 33, no. 6, pp. 1120-1136 . https://doi.org/10.1681/ASN.2021030294
J Am Soc Nephrol
Finch, N C, Fawaz, S, Neal, C R, Butler, M J, Salmon, A, Lay, A C, Stevens, M, Mellor, H H, Harper, S J, Welsh, G I, Foster, R & Satchell, S C 2022, ' Reduced glomerular filtration in diabetes is attributable to loss of density and increased resistance of glomerular endothelial cell fenestrations ', Journal of the American Society of Nephrology, vol. 33, no. 6, pp. 1120-1136 . https://doi.org/10.1681/ASN.2021030294
Background: Glomerular endothelial cell (GEnC) fenestrations are recognised as an essential component of the glomerular filtration barrier, yet little is known about how they are regulated and their role in disease.Methods: We comprehensively charact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8640d1b05cba480fd85861f51a3d378
https://doi.org/10.1681/asn.2021030294
https://doi.org/10.1681/asn.2021030294
Autor:
Megan Stevens, Christopher R Neal, Elena C Craciun, Maria Dronca, Steven J Harper, Sebastian Oltean
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212910 (2019)
There is evidence to suggest that abnormal angiogenesis, inflammation, and fibrosis drive diabetic nephropathy (DN). However, there is no specific treatment to counteract these processes. We aimed to determine whether DIAVIT, a natural Vaccinium myrt
Externí odkaz:
https://doaj.org/article/5e4eaef2b9e94f4f8c9cb71ee9ae353e
Autor:
Jennifer Trivedi, Megan Stevens
Publikováno v:
COVID-19, Frontline Responders and Mental Health: A Playbook for Delivering Resilient Public Health Systems Post-Pandemic ISBN: 9781802621181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46489e8adcfd7f5433a7aa081d658da7
https://doi.org/10.1108/978-1-80262-115-020231006
https://doi.org/10.1108/978-1-80262-115-020231006
Autor:
Megan Stevens, Sebastian Oltean
Publikováno v:
Cells, Vol 8, Iss 4, p 288 (2019)
Vascular endothelial growth factor A (VEGF-A) signaling is essential for physiological and pathological angiogenesis. Alternative splicing of the VEGF-A pre-mRNA gives rise to a pro-angiogenic family of isoforms with a differing number of amino acids
Externí odkaz:
https://doaj.org/article/c1d193b2af2742deb5cfc5cb24abf367
Autor:
Alun Stevens, Megan Stevens
Publikováno v:
History of Political Economy. 52:239-273
Professor Ronald H. Coase included his essays on Alfred Marshall in his book, Essays on Economics and Economists. Because of Coase’s standing as a Nobel laureate and professor of economics at the University of Chicago, these essays have been relied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a9cb2806c1fc60128db732edd0713b
https://doi.org/10.1215/00182702-8173310
https://doi.org/10.1215/00182702-8173310
Autor:
David O. Bates, Eleanor Star, Sebastian Oltean, Steve J Harper, Christopher W.J. Smith, Monica Lamici Ayine, Ling Li, Clare Gooding, Megan Stevens
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-12 (2021)
Oncogenesis
Oncogenesis
Funder: RCUK | Biotechnology and Biological Sciences Research Council (BBSRC); doi: https://doi.org/10.13039/501100000268
Funder: Diabetes UK; doi: https://doi.org/10.13039/501100000361
Alternative splicing of the vascular endothelial growt
Funder: Diabetes UK; doi: https://doi.org/10.13039/501100000361
Alternative splicing of the vascular endothelial growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e712dfbfd96868b2faa40bc0a68afc