Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Megan, Purl"'
Autor:
Greg M. Allen, Nicholas W. Frankel, Nishith R. Reddy, Hersh K. Bhargava, Maia A. Yoshida, Sierra R. Stark, Megan Purl, Jungmin Lee, Jacqueline L. Yee, Wei Yu, Aileen W. Li, K. Christopher Garcia, Hana El-Samad, Kole T. Roybal, Matthew H. Spitzer, Wendell A. Lim
Publikováno v:
Science (New York, N.Y.), vol 378, iss 6625
Chimeric antigen receptor (CAR) T cells are ineffective against solid tumors with immunosuppressive microenvironments. To overcome suppression, we engineered circuits in which tumor-specific synNotch receptors locally induce production of the cytokin
Autor:
Magdalena E. Potok, Zhenhui Zhong, Colette L. Picard, Qikun Liu, Truman Do, Cassidy E. Jacobsen, Ocean Sakr, Bilguudei Naranbaatar, Ruwan Thilakaratne, Zhanna Khnkoyan, Megan Purl, Harrison Cheng, Helena Vervaet, Suhua Feng, Shima Rayatpisheh, James A. Wohlschlegel, Ronan C. O’Malley, Joseph R. Ecker, Steven E. Jacobsen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 3
ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) AND ATXR6 are required for the deposition of H3K27me1 and for maintaining genomic stability in Arabidopsis Reduction of ATXR5/6 activity results in activation of DNA damage response genes, along with ti
Autor:
Magdalena E, Potok, Zhenhui, Zhong, Colette L, Picard, Qikun, Liu, Truman, Do, Cassidy E, Jacobsen, Ocean, Sakr, Bilguudei, Naranbaatar, Ruwan, Thilakaratne, Zhanna, Khnkoyan, Megan, Purl, Harrison, Cheng, Helena, Vervaet, Suhua, Feng, Shima, Rayatpisheh, James A, Wohlschlegel, Ronan C, O'Malley, Joseph R, Ecker, Steven E, Jacobsen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The plant-specific H3K27me1 methyltransferases ATXR5 and ATXR6 play integral roles connecting epigenetic silencing with genomic stability. However, how H3K27me1 relates to these processes is poorly understood. In this study, we performed