Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Megan, De Ste Croix"'
Autor:
Charlotte Davison, Sam Tallman, Megan de Ste-Croix, Martin Antonio, Marco R Oggioni, Brenda Kwambana-Adams, Fabian Freund, Sandra Beleza
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011317 (2024)
Evaluation of the apportionment of genetic diversity of human bacterial commensals within and between human populations is an important step in the characterization of their evolutionary potential. Recent studies showed a correlation between the geno
Externí odkaz:
https://doaj.org/article/b5c6e34f629d44248299919d85cd9d4c
Publikováno v:
MethodsX, Vol 10, Iss , Pp 102091- (2023)
Genome-wide association studies are a powerful approach for identifying determinants of disease. For infectious diseases, high throughput assays are required for measuring the variance in multiple virulence-related phenotypes of large bacterial isola
Externí odkaz:
https://doaj.org/article/6be8e8a55923474591f4aafe875f01f9
Autor:
Tinashe K. Nyazika, Lusako Sibale, Joseph Phiri, Megan De Ste Croix, Zydrune Jasiunaite, Christopher Mkandawire, Rose Malamba, Anstead Kankwatira, Miriam Manduwa, Daniela M. Ferreira, Tonney S. Nyirenda, Marco R. Oggioni, Henry C. Mwandumba, Kondwani C. Jambo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than HIV-uninfected adults, but the reasons for this are still not well understood. We investigated whether alveolar macrophages (AM) mediated control of pneumococcal i
Externí odkaz:
https://doaj.org/article/9787cdc7149e48cbabf475e2be0f354d
Autor:
Florian R. Zbinden, Megan De Ste Croix, Denis Grandgirard, Richard D. Haigh, Irene Vacca, Roxana Zamudio, Emily C. A. Goodall, Roger Stephan, Marco R. Oggioni, Stephen L. Leib
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Background:L. monocytogenes meningoencephalitis has a mortality rate of up to 50% and neurofunctional sequelae are common. Type I restriction-modification systems (RMS) are capable of adding methyl groups to the host genome. Some contain multiple seq
Externí odkaz:
https://doaj.org/article/232b76a7ff134a6a874b1a3ea8474134
Autor:
Claire Durmort, Giuseppe Ercoli, Elisa Ramos-Sevillano, Suneeta Chimalapati, Richard D. Haigh, Megan De Ste Croix, Katherine Gould, Jason Hinds, Yann Guerardel, Thierry Vernet, Marco Oggioni, Jeremy S. Brown
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The capsule is the dominant Streptococcus pneumoniae virulence factor, yet how variation in capsule thickness is regulated is poorly understood. Here, we describe an unexpected relationship between mutation of adcAII, which encodes a zinc up
Externí odkaz:
https://doaj.org/article/3c6b97acfd444f4693bf02410dff2bee
Autor:
Kate Cuthbert, Kierra Bunting, Megan De Ste Croix, Kerry Gough, Ellie Kennedy, Jelena Matic, Beck McCarter
Publikováno v:
International Journal for Academic Development. 27:327-329
Autor:
Tinashe K, Nyazika, Lusako, Sibale, Joseph, Phiri, Megan, De Ste Croix, Zydrune, Jasiunaite, Christopher, Mkandawire, Rose, Malamba, Anstead, Kankwatira, Miriam, Manduwa, Daniela M, Ferreira, Tonney S, Nyirenda, Marco R, Oggioni, Henry C, Mwandumba, Kondwani C, Jambo
Publikováno v:
Frontiers in immunology. 13
People Living with HIV (PLHIV) are at an increased risk of pneumococcal pneumonia than HIV-uninfected adults, but the reasons for this are still not well understood. We investigated whether alveolar macrophages (AM) mediated control of pneumococcal i
Autor:
Robeena Farzand, Evangelos Mourkas, Megan De Ste Croix, Neelam Dave, Abdullahi Jama, Neil Oldfield, Jay Lucidarme, David Turner, Ray Borrow, Luisa Martinez-Pomares, Samuel Sheppard, Christopher Bayliss
Publikováno v:
Access Microbiology. 4
Despite on-going vaccination programmes, Neisseria meningitidisis a majorcause of septicaemia and meningitis. In 2017-18, the MenW and MenY capsular groups caused 38% of all UK invasive meningococcal disease cases. Current policy is to generate genom
Autor:
Joanna Houghton, Teresa Cortes, Olga Schubert, Graham Rose, Angela Rodgers, Megan De Ste Croix, Rudolf Aebersold, Douglas B Young, Kristine B Arnvig
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80047 (2013)
Enhanced transcription of the Rv2660c locus in response to starvation of Mycobacterium tuberculosis H37Rv encouraged addition of the predicted Rv2660c protein to an improved vaccine formulation. Using strand-specific RNA sequencing, we show that the
Externí odkaz:
https://doaj.org/article/6cb5289777a5473ba41f7713e012bf4a
Autor:
Sara Escobar-Gonzalez, Jan-Willem Veening, Megan De Ste Croix, Chunhao Li, Guilin Wang, Xun Lan, Juanjuan Wang, Jing Li, Richard J. Roberts, Jing-Ren Zhang, Zeyao Li, Kurni Kurniyati, Joseph D. Ralph, Yijie Deng, Xue Liu, Yanni Liu, Marco R. Oggioni, Xueting Huang
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol. 48, no. 20, pp. 11468-11485
Nucleic acids research, vol. 48, no. 20, pp. 11468-11485
Type I restriction-modification (R-M) systems consist of a DNA endonuclease (HsdR, HsdM and HsdS subunits) and methyltransferase (HsdM and HsdS subunits). The hsdS sequences flanked by inverted repeats (referred to as epigenetic invertons) in certain