Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Meg Vemulapalli"'
1
Integrating cultivation and metagenomics for a multi-kingdom view of skin microbiome diversity and functions
Autor: Sara, Saheb Kashaf, Diana M, Proctor, Clay, Deming, Paul, Saary, Martin, Hölzer, Monica E, Taylor, Heidi H, Kong, Julia A, Segre, Alexandre, Almeida, Meg, Vemulapalli
Publikováno v: Nat Microbiol
Human skin functions as a physical barrier to foreign pathogen invasion and houses numerous commensals. Shifts in the human skin microbiome have been associated with conditions ranging from acne to atopic dermatitis. Previous metagenomic investigatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83662ee4c4bc7229511568caf8e84df
https://pubmed.ncbi.nlm.nih.gov/34952941
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4
Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma
Autor: Steven A. Rosenberg, Quino Maduro, Sean Lovett, Hannah Carter, Laura Elnitski, Sean Davis, Betty Benjamin, Nicholas K. Hayward, J. Lin, Michael D. Gregory, Chava Kimchi-Sarfaty, James Thomas, Michael A. Davies, Michael L. Stitzel, Rachel Karchin, Alice Young, Pam Thomas, Xiaobin Guan, Casandra Montemayor, Jesse Becker, Jamie K. Teer, Nancy Riebow, Shelise Brooks, Elliott H. Margulies, Gerry Bouffard, Holly Coleman, Jyoti Gupta, Brian L. Schmidt, Morgan Park, James C. Mullikin, Karen Schandler, Francis S. Collins, Cathy Masiello, Xiaomu Wei, Baishali Maskeri, Sujata Jha, William A. Robinson, Richelle Legaspi, Yardena Samuels, Shi-ling Ho, Steven E. Robinson, Christina Sison, Ken Dutton-Regester, Meg Vemulapalli, Todd D. Prickett, Jenny McDowell, Valer Gotea, Taccara Johnson, Nobuko H. Katagiri, Robert W. Blakesley, Umesh Bhanot, Guo Chen, Vijaya L. Simhadri, Stephen C. J. Parker, Jared J. Gartner, Mal Stantripop, Mila Dekhtyar, Jeffrey E. Gershenwald, Joel Han, Mario A. Morken, Giovanni Parmigiani, April Hargrove, Anton A. Komar
Publikováno v: Proceedings of the National Academy of Sciences. 110:13481-13486
Synonymous mutations, which do not alter the protein sequence, have been shown to affect protein function [Sauna ZE, Kimchi-Sarfaty C (2011) Nat Rev Genet 12(10):683–691]. However, synonymous mutations are rarely investigated in the cancer genomics
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73128767d86eb42c6e030e181b9b629f
https://doi.org/10.1073/pnas.1304227110
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5
Mining the antibodyome for HIV-1–neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains
Autor: John R. Mascola, Yongping Yang, Melissa Simek, S. Munir Alam, Christina Sison, Sean Lovett, April Hargrove, Julie Blinn, Robert W. Blakesley, Cathy Masiello, Nancy Riebow, Lawrence Shapiro, James C. Mullikin, Gabriel Lu, Jeff Skinner, Dennis R. Burton, Krisha McKee, Pam Thomas, Barton F. Haynes, Joshua Eudailey, Shi-ling Ho, Betty Benjamin, Nisc Comparative Sequencing Program, Holly Coleman, Jiang Zhu, Quino Maduro, Zhenhai Zhang, Mila Dekhtyar, Gilad Ofek, Karen Schandler, Joel Han, Richelle Legaspi, Jenny McDowell, Taccara Johnson, Mal Stantripop, Jesse Becker, Krissey E. Lloyd, James Thomas, Shelise Brooks, Gerry Bouffard, Alice Young, Baoshan Zhang, Meg Vemulapalli, Brian L. Schmidt, Marie Pancera, Peter D. Kwong, Mark K. Louder, Baishali Maskeri, Morgan Park, Robert Parks, Jyoti Gupta, Michael D. Gregory, Wayne C. Koff, Xiaobin Guan, Casandra Montemayor
Publikováno v: Proceedings of the National Academy of Sciences. 110:6470-6475
Next-generation sequencing of antibody transcripts from HIV-1–infected individuals with broadly neutralizing antibodies could provide an efficient means for identifying somatic variants and characterizing their lineages. Here, we used 454 pyroseque
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b087750599718ed65d8607625ce81ff2
https://doi.org/10.1073/pnas.1219320110
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6
A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope
Autor: Chung-Yi Wu, Michael Gregory, Brian P. Schmidt, Peter D. Kwong, Reda Rawi, Yongping Yang, Cathy Masiello, Chang-Chun D Lee, James C. Mullikin, Shi-ling Ho, Anqi Zheng, John R. Mascola, Karen Schandler, Richelle Legaspi, Holly Coleman, Chen-Hsiang Shen, Mila Dekhtyar, Catherine Stevenson, Vidya S. Shivatare, Joel Han, Rui Kong, Xiaobin Guan, Casandra Montemayor, Gwo-Yu Chuang, Dennis R. Burton, Krisha McKee, Jenny McDowell, Eric Waltari, Pam Thomas, Justin Taft, Chi-Huey Wong, Mal Stantripop, Sijy O'Dell, Xueling Wu, Morgan Park, Shelise Brooks, Meg Vemulapalli, Gerry Bouffard, Lawrence Shapiro, Mark K. Louder, Robert W. Blakesley, Baishali Maskeri, Victoria R. Polonis, Ivelin S. Georgiev, Sachin S. Shivatare, Yaroslav Tsybovsky, Baoshan Zhang, April Hargrove, Syna Gift, Tongqing Zhou, Betty Benjamin, Syed Shahzad-ul-Hussan, Alice Young, James W. Thomas, Carole A. Bewley, Jyoti Gupta, Guillaume Stewart-Jones, Quino Maduro, Nancy Riebow, Christina Sison, Robert T. Bailer, Ulrich Baxa
Publikováno v: Immunity. 48:500-513.e6
Summary Virtually the entire surface of the HIV-1-envelope trimer is recognized by neutralizing antibodies, except for a highly glycosylated region at the center of the "silent face" on the gp120 subunit. From an HIV-1-infected donor, #74, we identif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34ddd9d2ad313941c9715e018cf74cf
https://doi.org/10.1016/j.immuni.2018.02.013
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