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of 7
pro vyhledávání: '"Meg Schuurman"'
Autor:
Meg Schuurman, Madison Wallace, Gurleen Sahi, Malina Barillaro, Siyi Zhang, Mushfiqur Rahman, Cynthia Sawyez, Nica Borradaile, Rennian Wang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obesity plays a major role in type II diabetes (T2DM) progression because it applies metabolic and oxidative stress resulting in dysfunctional beta-cells and activation of intra-islet pancreatic stellate cells (PaSCs) which cause islet fibrosis. Admi
Externí odkaz:
https://doaj.org/article/8011e86d23284919a5c7b83b87ddba31
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
β1-integrin is a key receptor that regulates cell-ECM interactions and is important in maintaining mature beta-cell functions, including insulin secretion. However, there is little reported about the relationship between ECM-β1-integrin interaction
Externí odkaz:
https://doaj.org/article/802e909b92a7407398b090f862e705e2
Publikováno v:
Endocrinology. 164(1)
Shortcomings in cell-based therapies for patients with diabetes have been revealed to be, in part, a result of an improper extracellular matrix (ECM) environment. In vivo, pancreatic islets are emersed in a diverse ECM that provides physical support
Autor:
Meg Schuurman, Daniel L Peterson, Muhammad T. Padela, Joseph Wilkinson, Rahul Vaidya, Christopher J Kennedy, Andreea Geamanu
Publikováno v:
Journal of Orthopaedic Trauma. 34:376-381
Objectives To compare immediate internal fixation with primary wound closure to temporary fixation/stabilization with delayed fixation and wound closure protocols for management of open ankle fractures. Design Retrospective case-control study. Settin
Autor:
Yun Jin Chen, Kia M. Peters, Rennian Wang, Krisha Patel, Taylor Woolnough, John P. Kennelly, René L. Jacobs, Meg Schuurman, Kelly-Ann Leonard, Cynthia G. Sawyez, Rachel B. Wilson, Brian G. Sutherland, Richard Zhang, Nica M. Borradaile, Alexandra M. Hetherington
Publikováno v:
Paediatrics Publications
Inhibition of eukaryotic elongation factor 1A1 (EEF1A1) with the marine compound didemnin B decreases lipotoxic HepG2 cell death in vitro and improves early stage non-alcoholic fatty liver disease (NAFLD) in young genetically obese mice. However, the
Autor:
Krystalyn Mauch, Muhammad T. Padela, Ian Hudson, Rahul Vaidya, Petra Gheraibeh, Meg Schuurman
Publikováno v:
SICOT-J
SICOT-J, Vol 5, p 1 (2019)
SICOT-J, Vol 5, p 1 (2019)
Introduction: Locked intramedullary nailing (IMN) is the standard treatment for femoral shaft fractures in adults with high rates of union and relatively low rates of complications. Leg length discrepancy (LLD) after IMN of femoral shaft fractures is