Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Meetu, Kaushik Tiwari"'
Autor:
Yanfeng Liu, Adam Krysztofiak, Cynthia Chan, Meetu Kaushik Tiwari, W. Mark Saltzman, Daniel A. Colon-Rios, Eric Song, Elias Quijano, Hee-Won Suh, Hemanta C. Rao Tumu, Demetrios T. Braddock, Faye A. Rogers
Publikováno v:
Nature Biotechnology. 40:325-334
Gene amplification drives oncogenesis in a broad spectrum of cancers. A number of drugs have been developed to inhibit the protein products of amplified driver genes, but their clinical efficacy is often hampered by drug resistance. Here, we introduc
Autor:
Scott A. Strobel, Daniel Spakowicz, Meetu Kaushik Tiwari, Jason M. Crawford, Hyun Bong Park, Nneoma Adaku, Faye A. Rogers
Publikováno v:
Journal of natural products. 83(6)
Disruption of the tumor suppressor PTEN, either at the protein or genomic level, plays an important role in human cancer development. The high frequency of PTEN deficiency reported across several cancer subtypes positions therapeutic approaches that
Autor:
Meetu, Kaushik Tiwari, Daniel A, Colon-Rios, Hemanta C Rao, Tumu, Yanfeng, Liu, Elias, Quijano, Adam, Krysztofiak, Cynthia, Chan, Eric, Song, Demetrios T, Braddock, Hee-Won, Suh, W Mark, Saltzman, Faye A, Rogers
Publikováno v:
Nature biotechnology. 40(3)
Gene amplification drives oncogenesis in a broad spectrum of cancers. A number of drugs have been developed to inhibit the protein products of amplified driver genes, but their clinical efficacy is often hampered by drug resistance. Here, we introduc
Publikováno v:
Nucleic Acids Research
Structural alterations in DNA can serve as natural impediments to replication fork stability and progression, resulting in DNA damage and genomic instability. Naturally occurring polypurine mirror repeat sequences in the human genome can create endog
Autor:
Meetu Kaushik Tiwari, Faye A. Rogers
Publikováno v:
Nucleic Acids Research
DNA sequences capable of forming triplexes are prevalent in the human genome and have been found to be intrinsically mutagenic. Consequently, a balance between DNA repair and apoptosis is critical to counteract their effect on genomic integrity. Usin
Autor:
François Vrtovsnik, Laurent Mesnard, Francine Walker, Leona Raskova Kafkova, Ivan C. Moura, Bruce A. Julian, Renato C. Monteiro, Meetu Kaushik Tiwari, Martin Flamant, Niels Olsen Saraiva Camara, Marie Demion, Jan Novak, Emilie Tissandie, Jonathan M. Chemouny, Marc Benhamou, Houda Tamouza, Laureline Berthelot, Etienne Paubelle
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2012, 82 (12), pp.1284-1296. ⟨10.1038/ki.2012.192⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Kidney International, 2012, 82 (12), pp.1284-1296. ⟨10.1038/ki.2012.192⟩
Kidney International, Nature Publishing Group, 2012, 82 (12), pp.1284-1296. ⟨10.1038/ki.2012.192⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Kidney International, 2012, 82 (12), pp.1284-1296. ⟨10.1038/ki.2012.192⟩
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and has significant morbidity and mortality as 20–40% of patients progress to end-stage renal disease (ESRD) within 20 years after disease onset. We aimed to gain insigh
Autor:
Surinder P. Singh, Ajeet Kaushik, Jayant Kumar, Bansi D. Malhotra, Meetu Kaushik Tiwari, Gupta, Raju Khan
Publikováno v:
Journal of Nanoscience and Nanotechnology. 8:3749-3756
We present a hybrid fluid-particle algorithm to simulate flow and transport of DNA-laden fluids in microdevices. Relevant length scales in microfluidic systems range from characteristic channel sizes of millimeters to micron scale geometric variation
Autor:
Faye A, Rogers, Meetu Kaushik, Tiwari
Publikováno v:
The Yale Journal of Biology and Medicine
Cellular DNA damage response is critical to preserving genomic integrity following exposure to genotoxic stress. A complex series of networks and signaling pathways become activated after DNA damage and trigger the appropriate cellular response, incl
Autor:
Pierre Launay, Meryem Aloulou, Yutaka Kanamaru, Séverine Pfirsch-Maisonnas, Renato C. Monteiro, Ting Xu, Ulrich Blank, Julien Claver, Meetu Kaushik Tiwari
Publikováno v:
Science signaling. 4(169)
The ability of immunoreceptor tyrosine-based activation motif (ITAM)–bearing receptors to inhibit, rather than activate, signaling by other receptors is a regulatory mechanism of immune homeostasis. However, it remains unclear how inhibitory ITAM (
Polymeric IgA1 controls erythroblast proliferation and accelerates erythropoiesis recovery in anemia
Autor:
Damien Grapton, Marie-Alexandra Alyanakian, Virginie Pascal, Michael Dussiot, Tomas Leanderson, Thiago Trovati Maciel, Olivier Hermine, Marc Benhamou, Séverine Coulon, Renato C. Monteiro, Patrick Mayeux, Kamel Djedaini, Zeliha Oruc, Julie Vandekerckhove, Saurabh Agarwal, Meetu Kaushik Tiwari, Michel Cogné, Ivan C. Moura, Bertrand Arnulf, Houda Tamouza, Geneviève Courtois, Aurélie Fricot, Pamella Huey Mei Wang, Yael Zermati, Jean-Antoine Ribeil, Céline Callens
Publikováno v:
Nature Medicine
Nature Medicine, Nature Publishing Group, 2011, 17, pp.1456-1465
Nature Medicine, Nature Publishing Group, 2011, 17 (11), pp.1456-65. ⟨10.1038/nm.2462⟩
Nature Medicine, Nature Publishing Group, 2011, 17 (11), pp.1456-65. 〈10.1038/nm.2462〉
Nature Medicine, Nature Publishing Group, 2011, 17, pp.1456-1465
Nature Medicine, Nature Publishing Group, 2011, 17 (11), pp.1456-65. ⟨10.1038/nm.2462⟩
Nature Medicine, Nature Publishing Group, 2011, 17 (11), pp.1456-65. 〈10.1038/nm.2462〉
International audience; Anemia because of insufficient production of and/or response to erythropoietin (Epo) is a major complication of chronic kidney disease and cancer. The mechanisms modulating the sensitivity of erythroblasts to Epo remain poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5e5906a1d3655353ee4dc190ee27e8
https://hal.archives-ouvertes.fr/hal-00617557
https://hal.archives-ouvertes.fr/hal-00617557