Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Meera V. Singh"'
Autor:
Meera V. Singh, Md Nasir Uddin, Mae Covacevich Vidalle, Karli R. Sutton, Zachary D. Boodoo, Angelique N. Peterson, Alicia Tyrell, Madalina E. Tivarus, Henry Z. Wang, Bogachan Sahin, Jianhui Zhong, Miriam T. Weber, Lu Wang, Xing Qiu, Sanjay B. Maggirwar, Giovanni Schifitto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundDespite antiretroviral treatment (cART), aging people living with HIV (PWH) are more susceptible to neurocognitive impairment (NCI) probably due to synergistic/additive contribution of traditional cerebrovascular risk factors. Specifically,
Externí odkaz:
https://doaj.org/article/966b402f354c448595e8a92f0ba94bfe
Autor:
Meera V. Singh, Md Nasir Uddin, Vir B. Singh, Angelique N. Peterson, Kyle D. Murray, Yuchuan Zhuang, Alicia Tyrell, Lu Wang, Madalina E. Tivarus, Jianhui Zhong, Xing Qiu, Giovanni Schifitto
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionDue to advances in combined anti-retroviral treatment (cART), there is an increased burden of age-related cerebrovascular disease (CBVD), in people living with HIV (PWH). The underlying CNS injury can be assessed by measuring cerebral blo
Externí odkaz:
https://doaj.org/article/c240987fa02249898f65da6daee56079
Autor:
Mukta G. Palshikar, Rohith Palli, Alicia Tyrell, Sanjay Maggirwar, Giovanni Schifitto, Meera V. Singh, Juilee Thakar
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Atherosclerosis (AS)-associated cardiovascular disease is an important cause of mortality in an aging population of people living with HIV (PLWH). This elevated risk has been attributed to viral infection, anti-retroviral therapy, chronic in
Externí odkaz:
https://doaj.org/article/50363a7200394f4d9c6f1fb1823f2de9
Autor:
Adam Cornwell, Rohith Palli, Meera V. Singh, Lauren Benoodt, Alicia Tyrell, Jun-ichi Abe, Giovanni Schifitto, Sanjay B. Maggirwar, Juilee Thakar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract People living with HIV are at higher risk of atherosclerosis (AS). The pathogenesis of this risk is not fully understood. To assess the regulatory networks involved in AS we sequenced mRNA of the peripheral blood mononuclear cells (PBMCs) an
Externí odkaz:
https://doaj.org/article/50c82d93ef8840fd8ec8d9ebf2e6750a
Autor:
Kyle D. Murray, Md Nasir Uddin, Madalina E. Tivarus, Bogachan Sahin, Henry Z. Wang, Meera V. Singh, Xing Qiu, Lu Wang, Pascal Spincemaille, Yi Wang, Sanjay B. Maggirwar, Jianhui Zhong, Giovanni Schifitto
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102786- (2021)
The aim of this study was to assess, in the context of cerebral small vessel disease (CSVD), whether cardiovascular risk factors and white matter hyperintensities (WMHs) were associated with brain tissue susceptibility as measured by quantitative sus
Externí odkaz:
https://doaj.org/article/79807b13a428435d86b533eb16f676c7
Autor:
Kyle D. Murray, Meera V. Singh, Yuchuan Zhuang, Md Nasir Uddin, Xing Qiu, Miriam T. Weber, Madalina E. Tivarus, Henry Z. Wang, Bogachan Sahin, Jianhui Zhong, Sanjay B. Maggirwar, Giovanni Schifitto
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Rationale: We provide an in-depth description of a comprehensive clinical, immunological, and neuroimaging study that includes a full image processing pipeline. This approach, although implemented in HIV infected individuals, can be used in the gener
Externí odkaz:
https://doaj.org/article/666ea52b702e47338d29c9d84ccf95ce
Autor:
Emily A. Weber, Meera V. Singh, Vir B. Singh, Joseph W. Jackson, Sara K. Ture, Sumanun Suwunnakorn, Craig N. Morrell, Sanjay B. Maggirwar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 17 (2020)
Background Microvesicles are cell membrane–derived vesicles that have been shown to augment inflammation. Specifically, monocyte‐derived microvesicles (MDMVs), which can express the coagulation protein tissue factor, contribute to thrombus format
Externí odkaz:
https://doaj.org/article/72cf705b06c24b648bf055402bed22c9
Autor:
Meera V Singh, Md Nasir Uddin, Mae Covacevich Vidalle, Karli R. Sutton, Zachary D. Boodoo, Angelique N. Peterson, Alicia Tyrell, Raeann Brenner, Madalina E Tivarus, Henry Z. Wang, Bogachan Sahin, Jianhui Zhong, Miriam Weber, Lu Wang, Xing Qiu, Sanjay B. Maggiwar, Giovanni Schifitto
Publikováno v:
medRxiv
Despite antiretroviral treatment (cART), people living with HIV (PLWH) are more susceptible to neurocognitive impairment (NCI), probably due to synergistic/additive contribution of traditional cerebrovascular risk factors. Specifically, altered blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b735a3b0c1b5f7dd4e623272b5504ac6
https://doi.org/10.1101/2023.03.24.23287660
https://doi.org/10.1101/2023.03.24.23287660
Publikováno v:
Journal of NeuroVirology. 28:305-311
We previously showed that HIV-1 can alter the expression of tight junction proteins by downregulating Sonic hedgehog (Shh) signaling, thereby disrupting blood–brain barrier (BBB) integrity. In this study, we employed a conditional, CNS specific, Ta
Autor:
Lauren Benoodt, Juilee Thakar, Jun Ichi Abe, Sanjay B. Maggirwar, Rohith Palli, Alicia Tyrell, Meera V. Singh, Adam Cornwell, Giovanni Schifitto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
People living with HIV are at higher risk of atherosclerosis (AS). The pathogenesis of this risk is not fully understood. To assess the regulatory networks involved in AS we sequenced mRNA of the peripheral blood mononuclear cells (PBMCs) and measure