Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Meera Swami"'
Autor:
Stéphanie Tomé, Kevin Manley, Jodie P Simard, Greg W Clark, Meghan M Slean, Meera Swami, Peggy F Shelbourne, Elisabeth R M Tillier, Darren G Monckton, Anne Messer, Christopher E Pearson
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003280 (2013)
Expansions of trinucleotide CAG/CTG repeats in somatic tissues are thought to contribute to ongoing disease progression through an affected individual's life with Huntington's disease or myotonic dystrophy. Broad ranges of repeat instability arise be
Externí odkaz:
https://doaj.org/article/e0bb9127dfe5406088d109096406ad81
Autor:
Meera Swami
Publikováno v:
Nature Reviews Genetics. 16:684-685
Autor:
Meera Swami
Publikováno v:
Nature reviews. Genetics. 11(3)
Autor:
Meera, Swami
Publikováno v:
Nature reviews. Genetics. 11(12)
Autor:
Meera, Swami
Publikováno v:
Nature reviews. Genetics. 11(10)
Genetic conflicts between sexes and generations provide a foundation for understanding the functional evolution of sex chromosomes and sexually dimorphic phenotypes. Y chromosomes of Drosophila contain multi-megabase stretches of satellite DNA repeat
Autor:
Meera, Swami
Publikováno v:
Nature reviews. Cancer. 10(9)
Autor:
Meera, Swami
Publikováno v:
Nature
Summary MicroRNAs (miRNAs) are endogenous ∼22-nucleotide RNAs that play important gene-regulatory roles by pairing to the mRNAs of protein-coding genes to direct their repression. Repression of these regulatory targets leads to decreased translatio
Autor:
Meera, Swami
Publikováno v:
Nature
The canonical role of messenger RNA (mRNA) is to deliver protein-coding information to sites of protein synthesis. However, given that microRNAs bind to RNAs, we hypothesized that RNAs possess a biological role in cancer cells that relies upon their
Autor:
Meera Swami
Publikováno v:
Nature reviews. Cancer. 10(7)
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We report here that promoter-proximal pausing
Autor:
Meera, Swami
Publikováno v:
Nature reviews. Genetics. 11(8)