Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Meera, Shanmuganathan"'
Autor:
Tomás Clive Barker-Tejeda, Elisa Zubeldia-Varela, Andrea Macías-Camero, Lola Alonso, Isabel Adoración Martín-Antoniano, María Fernanda Rey-Stolle, Leticia Mera-Berriatua, Raphaëlle Bazire, Paula Cabrera-Freitag, Meera Shanmuganathan, Philip Britz-McKibbin, Carles Ubeda, M. Pilar Francino, Domingo Barber, María Dolores Ibáñez-Sandín, Coral Barbas, Marina Pérez-Gordo, Alma Villaseñor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The human gut microbiome establishes and matures during infancy, and dysregulation at this stage may lead to pathologies later in life. We conducted a multi-omics study comprising three generations of family members to investigate the early
Externí odkaz:
https://doaj.org/article/bce91622561c4bab9562e96f74ef59be
Autor:
Sandi M Azab, Meera Shanmuganathan, Russell J de Souza, Zachary Kroezen, Dipika Desai, Natalie C Williams, Katherine M Morrison, Stephanie A Atkinson, Koon K Teo, Meghan B Azad, Elinor Simons, Theo J Moraes, Piush J Mandhane, Stuart E Turvey, Padmaja Subbarao, Philip Britz-McKibbin, Sonia S Anand
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Childhood obesity is a global health concern and can lead to lifetime cardiometabolic disease. New advances in metabolomics can provide biochemical insights into the early development of obesity, so we aimed to characterize serum
Externí odkaz:
https://doaj.org/article/af6d3e803bc74e65ac64b8014ecf71fc
Autor:
Talha Rafiq, Jennifer C. Stearns, Meera Shanmuganathan, Sandi M. Azab, Sonia S. Anand, Lehana Thabane, Joseph Beyene, Natalie C. Williams, Katherine M. Morrison, Koon K. Teo, Philip Britz-McKibbin, Russell J. de Souza
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16651- (2023)
Evidence supports a complex interplay of gut microbiome and host metabolism as regulators of obesity. The metabolic phenotype and microbial metabolism of host diet may also contribute to greater obesity risk in children early in life. This study aime
Externí odkaz:
https://doaj.org/article/6ed42faccc7d40a695c21969a3a1dc57
Autor:
Sandi M. Azab, Russell J. de Souza, Amel Lamri, Meera Shanmuganathan, Zachary Kroezen, Karleen M. Schulze, Dipika Desai, Natalie C. Williams, Katherine M. Morrison, Stephanie A. Atkinson, Koon K. Teo, Philip Britz-McKibbin, Sonia S. Anand
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background Defining the metabolic syndrome (MetS) in children remains challenging. Furthermore, a dichotomous MetS diagnosis can limit the power to study associations. We sought to characterize the serum metabolite signature of the MetS in e
Externí odkaz:
https://doaj.org/article/8cf6b0dcf3f141f289bb4946e79559f3
Autor:
Brittany C. MacIntyre, Meera Shanmuganathan, Shannon L. Klingel, Zachary Kroezen, Erick Helmeczi, Na-Yung Seoh, Vanessa Martinez, Adrian Chabowski, Zeny Feng, Philip Britz-McKibbin, David M. Mutch
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1071 (2023)
The Omega-3 Index (O3I) reflects eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) content in erythrocytes. While the O3I is associated with numerous health outcomes, its widespread use is limited. We investigated whether urinary metabolites
Externí odkaz:
https://doaj.org/article/b8e4897cd64c4913a62d68856c4b1663
Autor:
Russell J de Souza, Milan Gupta, Koon Teo, Sonia S Anand, Dipika Desai, Claudia Sikorski, Sandi Azab, Meera Shanmuganathan, Stephanie A Atkinson, Katherine Morrison, Philip Britz-McKibbin
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/535bab961a6347ff89aba368cfaeac79
Autor:
Meera Shanmuganathan, Mohammad Omair Sarfaraz, Zachary Kroezen, Holly Philbrick, Richel Poon, Andrew Don-Wauchope, Marco Puglia, David Wishart, Philip Britz-McKibbin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Metabolomics offers new insights into disease mechanisms that is enhanced when adopting orthogonal instrumental platforms to expand metabolome coverage, while also reducing false discoveries by independent replication. Herein, we report the first int
Externí odkaz:
https://doaj.org/article/ce0a2d6fa76c4fe3a64d2fab74bd0533
Autor:
Meera Shanmuganathan, Meghan Bogert, Zachary Kroezen, Philip Britz-McKibbin, Stephanie A. Atkinson
Publikováno v:
The Journal of Nutrition. 153:999-1007
The Relationship Between Diet, Gut Microbiota, and Serum Metabolome of South Asian Infants at 1 Year
Autor:
Colin Y. Bruce, Meera Shanmuganathan, Sandi M. Azab, Elinor Simons, Piushkumar Mandhane, Stuart E. Turvey, Padmaja Subbarao, Meghan B. Azad, Philip Britz-McKibbin, Sonia S. Anand, Russell J. de Souza, Jennifer C. Stearns
Publikováno v:
The Journal of Nutrition. 153:470-482
Autor:
Mangalakumari Jeyanathan, Maryam Vaseghi-Shanjani, Sam Afkhami, Jensine A. Grondin, Alisha Kang, Michael R. D’Agostino, Yushi Yao, Shreya Jain, Anna Zganiacz, Zachary Kroezen, Meera Shanmuganathan, Ramandeep Singh, Anna Dvorkin-Gheva, Philip Britz-McKibbin, Waliul I. Khan, Zhou Xing
Publikováno v:
Nature Immunology. 23:1687-1702
Aside from centrally induced trained immunity in the bone marrow (BM) and peripheral blood by parenteral vaccination or infection, evidence indicates that mucosal-resident innate immune memory can develop via a local inflammatory pathway following mu