Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.

Autor: Replogle JM; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA.; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA., Norman TM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA.; Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xu A; Medical Scientist Training Program, University of California, San Francisco, San Francisco, CA, USA.; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA., Hussmann JA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA.; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA., Chen J; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA., Cogan JZ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA., Meer EJ; 10x Genomics Inc., Pleasanton, CA, USA., Terry JM; 10x Genomics Inc., Pleasanton, CA, USA., Riordan DP; 10x Genomics Inc., Pleasanton, CA, USA., Srinivas N; 10x Genomics Inc., Pleasanton, CA, USA., Fiddes IT; 10x Genomics Inc., Pleasanton, CA, USA., Arthur JG; 10x Genomics Inc., Pleasanton, CA, USA., Alvarado LJ; 10x Genomics Inc., Pleasanton, CA, USA., Pfeiffer KA; 10x Genomics Inc., Pleasanton, CA, USA., Mikkelsen TS; 10x Genomics Inc., Pleasanton, CA, USA., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. jonathan.weissman@ucsf.edu.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA. jonathan.weissman@ucsf.edu.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA, USA. jonathan.weissman@ucsf.edu., Adamson B; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA. badamson@princeton.edu.; Department of Molecular Biology, Princeton University, Princeton, NJ, USA. badamson@princeton.edu.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2020 Aug; Vol. 38 (8), pp. 954-961. Date of Electronic Publication: 2020 Mar 30.

The macula densa prorenin receptor is essential in renin release and blood pressure control.

Autor: Riquier-Brison ADM; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Sipos A; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Prókai Á; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Vargas SL; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Toma L; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Meer EJ; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Villanueva KG; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Chen JCM; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Gyarmati G; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Yih C; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Tang E; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Nadim B; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Pendekanti S; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California., Garrelds IM; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam , The Netherlands., Nguyen G; Centre for Interdisciplinary Research in Biology, UMR INSERM U1050, Collège de France, Paris , France., Danser AHJ; Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, Rotterdam , The Netherlands., Peti-Peterdi J; Departments of Physiology and Neuroscience, and Medicine, Zilkha Neurogenetic Institute, University of Southern California , Los Angeles, California.

Publikováno v: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2018 Sep 01; Vol. 315 (3), pp. F521-F534. Date of Electronic Publication: 2018 Apr 18.

Identification of a cis-acting element that localizes mRNA to synapses.

Autor: Meer EJ; Department of Biological Chemistry, University of California, Los Angeles, CA 90095, USA., Wang DO, Kim S, Barr I, Guo F, Martin KC

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2012 Mar 20; Vol. 109 (12), pp. 4639-44. Date of Electronic Publication: 2012 Mar 01.

The collecting duct is the major source of prorenin in diabetes.

Autor: Kang JJ; Department of Physiology, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Toma I, Sipos A, Meer EJ, Vargas SL, Peti-Peterdi J

Publikováno v: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2008 Jun; Vol. 51 (6), pp. 1597-604. Date of Electronic Publication: 2008 Apr 14.

Detection of drug interactions with single dose acenocoumarol: new screening method?

Autor: Kroon C; Center for Human Drug Research, University Hospital Leiden, The Netherlands., de Boer A, Hoogkamer JF, Schoemaker HC, van der Meer EJ, Edelbroek PM, Cohen AF

Publikováno v: International journal of clinical pharmacology, therapy, and toxicology [Int J Clin Pharmacol Ther Toxicol] 1990 Aug; Vol. 28 (8), pp. 355-60.