New Strategies for Forward Genetic Screening and Single Cell Analysis with CRISPRi Transcriptional Repressors

Autor: Ravanelli, Andrew, Meer, Elliott, Terry, Jessica, Ji, Qingzhou, Ashworth, Roxann, Chittur, Sridar

Publikováno v: J Biomol Tech

The power of CRISPR-Cas9 for genome engineering has continued to grow in recent years. The ability to perform large-scale, whole genome loss-of-function screens has allowed for new breakthroughs identifying gene pathways in drug resistance and diseas

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https://europepmc.org/articles/PMC7424921/

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Cellular and Molecular Mechanisms Underlying Long-Term Synaptic Plasticity: mRNA Localization and Synapse to Nuclear Signaling

Autor: Meer, Elliott

Publikováno v: Meer, Elliott. (2014). Cellular and Molecular Mechanisms Underlying Long-Term Synaptic Plasticity: mRNA Localization and Synapse to Nuclear Signaling. UCLA: Biological Chemistry 0117. Retrieved from: http://www.escholarship.org/uc/item/8bj862r2

Synaptic plasticity, changes in the number and strength of synaptic connections in the brain, represents the best-characterized correlate of learning and memory. Long-term synaptic plasticity is a transcription- and translation-dependent process that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::fe1f8e536c3a06dd0ec46173a7228097
http://www.escholarship.org/uc/item/8bj862r2

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