Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Meenu R. Pillai"'
Autor:
Jocelyn G. Labombarde, Meenu R. Pillai, Marie Wehenkel, Chun-Yang Lin, Rachael Keating, Scott A. Brown, Jeremy Chase Crawford, David C. Brice, Ashley H. Castellaw, Alexandra H. Mandarano, Clifford S. Guy, Juan R. Mejia, Carlessia D. Lewis, Ti-Cheng Chang, Christine M. Oshansky, Sook-San Wong, Richard J. Webby, Mei Yan, Quan–Zhen Li, Tony N. Marion, Paul G. Thomas, Maureen A. McGargill
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110482- (2022)
Summary: Infection and vaccination repeatedly expose individuals to antigens that are conserved between influenza virus subtypes. Nevertheless, antibodies recognizing variable influenza epitopes greatly outnumber antibodies reactive against conserved
Externí odkaz:
https://doaj.org/article/ca04b47d87454606930f357a2413f564
Autor:
Meenu R. Pillai, Belgacem Mihi, Kiminori Nakamura, Mark Bix, Mathew L. Coleman, David B. Finkelstein, Maureen A. McGargill, Toshinori Nakayama, Tokiyoshi Ayabe, Kenji Ishiwata, Naoya Sakuragi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0211244 (2019)
PLoS ONE, Vol 14, Iss 2, p e0211244 (2019)
Expulsion of parasitic gastrointestinal nematodes requires diverse effector mechanisms coordinated by a Th2-type response. The evolutionarily conserved JmjC protein; Myc Induced Nuclear Antigen (Mina) has been shown to repress IL4, a key Th2 cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fbf2547183322e13d84468316bf78f
https://pubmed.ncbi.nlm.nih.gov/30807587
https://pubmed.ncbi.nlm.nih.gov/30807587
Autor:
David Finkelstein, Xiaohua Wang, Kelli L. Boyd, Thomas S. Griffith, Thomas A. Ferguson, Andrea L. Szymczak-Workman, Teresa A. Doggett, Meenu R. Pillai, Lauren W. Collison, Jerold E. Rehg, Dario A. A. Vignali
Publikováno v:
The Journal of Immunology. 187:4987-4997
Regulatory T cells (Tregs) can suppress a wide variety of cell types, in diverse organ sites and inflammatory conditions. Whereas Tregs possess multiple suppressive mechanisms, the number required for maximal function is unclear. Furthermore, whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74852d68d38c2d012b2e60400e0dae39
https://doi.org/10.4049/jimmunol.1102173
https://doi.org/10.4049/jimmunol.1102173
Autor:
Meenu R. Pillai, Mark Bix
Publikováno v:
Growth Factors. 29:153-160
Interleukin-4 (IL4) is a pleiotropic cytokine involved in host protection from gastrointestinal nematodes. Here, we review the structure, function, and evolutionary history of IL4. Cumulative evidence indicates that over 100 million years of eutheria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e893acc3657e47e07a855721692ed805
https://doi.org/10.3109/08977194.2011.590138
https://doi.org/10.3109/08977194.2011.590138
Publikováno v:
Molecular Immunology. 44:1691-1703
Workshop cluster 1(+) gamma delta (WC1(+)gammadelta) T cells have been shown to play important roles in the immune response to infections. WC1 is a transmembrane glycoprotein, uniquely expressed on the surface of gammadelta T cells of ruminants and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a921b77dc9ddc73aeff61445f79355
https://doi.org/10.1016/j.molimm.2006.08.009
https://doi.org/10.1016/j.molimm.2006.08.009
Autor:
Andrew M. Fry, Meenu R. Pillai, Joanne E. Baxter, Ciara Twomey, Samantha L. Wattam, Joseph Rapley
Publikováno v:
Developmental Biology. 265:384-398
Pronuclear migration and formation of the first mitotic spindle depend upon assembly of a functional zygotic centrosome. For most animals, this involves both paternal and maternal contributions as sperm basal bodies are converted into centrosomes com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9460d596c9a87df62890ec9f3db99875
https://doi.org/10.1016/j.ydbio.2003.10.001
https://doi.org/10.1016/j.ydbio.2003.10.001
The JmjC protein Mina is an important immune response regulator. Classical forward genetics first discovered its immune role in 2009 in connection with the development of T helper 2 (Th2) cells. This prompted investigation into Mina's role in the two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238bbbecc01dc0b7f82e8565aaf07fcb
https://europepmc.org/articles/PMC4277203/
https://europepmc.org/articles/PMC4277203/
Autor:
Melanie Van Stry, Meenu R. Pillai, Makiko Watanabe, Linda Chung, Hari Hara Potula, Madoka Koyanagi, Shangli Lian, Mark Bix
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e80638 (2013)
PLoS ONE, Vol 8, Iss 12, p e80638 (2013)
Mina is an epigenetic gene regulatory protein known to function in multiple physiological and pathological contexts, including pulmonary inflammation, cell proliferation, cancer and immunity. We showed previously that the level of Mina gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a2aec8239475151290bac3a6514494
http://europepmc.org/articles/PMC3851307
http://europepmc.org/articles/PMC3851307
Autor:
Xin Lu, Mark Bix, Jaroslav Zak, R Sekirnik, Mathew L. Coleman, H Smith, Christopher J. Schofield, Peter J. Ratcliffe, A Zayer, Meenu R. Pillai
Publikováno v:
European Journal of Cancer. 61:S91
ydroxylation is an emerging modification catalysed by a family of ‘2-oxoglutarate (2OG)-dependent oxygenases’ that includes the Collagen and HIF hydroxylases, TET 5hmC demethylases, and JmjC histone demethylases. These enzymes are widely implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e143e9e8e0b6170a383700ad4122bf
https://doi.org/10.1016/s0959-8049(16)61319-9
https://doi.org/10.1016/s0959-8049(16)61319-9
Autor:
Youjin Lee, Hongkun Park, Hulin Jin, Sheng Xiao, Alex K. Shalek, David Gennert, Diana Lu, Mathew L. Coleman, Marsela Jorgolli, Nir Yosef, Dean Tantin, Chuan Wu, Peter J. Ratcliffe, Meenu R. Pillai, John J. Trombetta, Jellert T. Gaublomme, Rahul Satija, Amit Awasthi, Arvind Shakya, Katarzyna Karwacz, Aviv Regev, Vijay K. Kuchroo, Mark Bix
Publikováno v:
Nature
Despite their importance, the molecular circuits that control the differentiation of naive T cells remain largely unknown. Recent studies that reconstructed regulatory networks in mammalian cells have focused on short-term responses and relied on per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d875fd30ae5080d3d2eb1b18e2d281
https://pubmed.ncbi.nlm.nih.gov/23493117
https://pubmed.ncbi.nlm.nih.gov/23493117