Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Meenu N. Perera"'
Publikováno v:
Food Microbiology. 52:42-48
ListShield™, a commercially available bacteriophage cocktail that specifically targets Listeria monocytogenes, was evaluated as a bio-control agent for L. monocytogenes in various Ready-To-Eat foods. ListShield™ treatment of experimentally contam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1c29419e9cb48a89990d027d7df138
https://doi.org/10.1016/j.fm.2015.06.006
https://doi.org/10.1016/j.fm.2015.06.006
Publikováno v:
Biophysical Journal. 101(9):2163-2169
When activated, the proapoptotic protein Bax permeabilizes the mitochondrial outer membrane, allowing the release of proteins into the cytosol and thus initiating the execution phase of apoptosis. When activated Bax was reconstituted into phospholipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a33c1b31c4ea580e5e65229594cd139
Autor:
Vidyaramanan Ganesan, Meenu N. Perera, Debra Datskovskiy, David Colombini, Marco Colombini, Kirti Chadha
Publikováno v:
Apoptosis. 15:553-562
A critical step in apoptosis is mitochondrial outer membrane permeabilization (MOMP), releasing proteins critical to downstream events. While the regulation of this process by Bcl-2 family proteins is known, the role of ceramide, which is known to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6450857d9c86a2acea97ebd5499ece1
https://doi.org/10.1007/s10495-009-0449-0
https://doi.org/10.1007/s10495-009-0449-0
Autor:
Marco Colombini, Vidyaramanan Ganesan, Zdzislaw M. Szulc, Meenu N. Perera, Robert Bittman, Leah J. Siskind, Alicja Bielawska
Publikováno v:
Chemistry and physics of lipids. 194
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d3eb32da96cd86f31c3b8ec44e5e4e
https://pubmed.ncbi.nlm.nih.gov/26408265
https://pubmed.ncbi.nlm.nih.gov/26408265
Autor:
Meenu N. Perera, Johnny Stiban
Publikováno v:
Biochimica et biophysica acta. 1848(2)
Mitochondria mediate both cell survival and death. The intrinsic apoptotic pathway is initiated by the permeabilization of the mitochondrial outer membrane to pro-apoptotic inter-membrane space (IMS) proteins. Many pathways cause the egress of IMS pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5491d5c54eed5ffda0258fb56bd59079
https://pubmed.ncbi.nlm.nih.gov/25462172
https://pubmed.ncbi.nlm.nih.gov/25462172
Autor:
Shang H. Lin, Marco Colombini, Yuri K. Peterson, Alicja Bielawska, Zdzislaw M. Szulc, Meenu N. Perera, Robert Bittman
Publikováno v:
The Biochemical journal. 445(1)
The present study demonstrates the important structural features of ceramide required for proper regulation, binding and identification by both pro-apoptotic and anti-apoptotic Bcl-2 family proteins. The C-4=C-5 trans-double bond has little influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed669f725b42e3ef7be1557f830feecf
https://pubmed.ncbi.nlm.nih.gov/22494048
https://pubmed.ncbi.nlm.nih.gov/22494048
Publikováno v:
Biophysical Journal. 102(3)
The sphingolipid, ceramide can self-assemble in phospholipid membranes to form large channels capable of translocating proteins through membranes. Electronmicroscopic visualization and electrophysiological measurements reveal a range of pore sizes wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b40a2c1a6bfe138da30df2858635843
Publikováno v:
Biophysical Journal. 100(3)
Ceramide is a sphingolipid that has been shown to play a vital role in the commitment of a cell to apoptosis. There is increasing evidence that ceramide channels may be the pathway through which cytochrome c is released from mitochondria, a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef25f836f4079a2a95003d3bbe77d97b
Publikováno v:
Biophysical Journal. 100(3)
The sphingolipid, ceramide, forms channels capable of translocating proteins through membranes. These channels can form in the mitochondrial outer membrane at ceramide levels found to be present in that membrane early in apoptosis. For these channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291eec2078a0b8b1e40c8c6e61abaf01
Publikováno v:
Biophysical Journal. 98(3)
The pro-apoptotic protein, Bax, and the sphingolipid, ceramide, can individually form channels in phospholipid membranes. When combined, they permeabilize membranes in a synergistic way, indicating the formation of a combined channel structure. Nanom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0089b0a42c034b2fd7bcc9f8e4a0da68