Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Meenu Kesarwani"'
Autor:
Peipei Lin, Yanling Ren, Xiaomei Yan, Yingwan Luo, Hua Zhang, Meenu Kesarwani, Jiachen Bu, Di Zhan, Yile Zhou, Yuting Tang, Shuanghong Zhu, Weilai Xu, Xinping Zhou, Chen Mei, Liya Ma, Li Ye, Chao Hu, Mohammad Azam, Wei Ding, Jie Jin, Gang Huang, Hongyan Tong
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
Although cytarabine has been widely considered as one of the chemotherapy drugs for high-risk myelodysplastic syndromes (MDS), the overall response rate is only approximately 20-30%. Nuclear factor erythroid 2-related factor 2 (NRF2, also called NFE2
Externí odkaz:
https://doaj.org/article/3a3382b215a34648849e2b6936acfa37
Autor:
Yok-Ai Que, Ronen Hazan, Benjamin Strobel, Damien Maura, Jianxin He, Meenu Kesarwani, Panagiotis Panopoulos, Amy Tsurumi, Marlyse Giddey, Julie Wilhelmy, Michael N Mindrinos, Laurence G Rahme
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80140 (2013)
Bacteria can be refractory to antibiotics due to a sub-population of dormant cells, called persisters that are highly tolerant to antibiotic exposure. The low frequency and transience of the antibiotic tolerant "persister" trait has complicated eluci
Externí odkaz:
https://doaj.org/article/b38cfb4d3a6e412e8d8a0fd237aea9d7
Autor:
Arunava Bandyopadhaya, Meenu Kesarwani, Yok-Ai Que, Jianxin He, Katie Padfield, Ronald Tompkins, Laurence G Rahme
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003024 (2012)
Increasing evidence indicates that bacterial quorum sensing (QS) signals are important mediators of immunomodulation. However, whether microbes utilize these immunomodulatory signals to maintain infection remain unclear. Here, we show that the Pseudo
Externí odkaz:
https://doaj.org/article/1df41f842e9f430d85e974b8c7346786
Autor:
Meenu Kesarwani, Ronen Hazan, Jianxin He, Yok-Ai Que, Yiorgos Apidianakis, Biliana Lesic, Gaoping Xiao, Valérie Dekimpe, Sylvain Milot, Eric Deziel, François Lépine, Laurence G Rahme
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8, p e1002192 (2011)
A significant number of environmental microorganisms can cause serious, even fatal, acute and chronic infections in humans. The severity and outcome of each type of infection depends on the expression of specific bacterial phenotypes controlled by co
Externí odkaz:
https://doaj.org/article/c53aaff4f52c467bb84d7a12c1a74944
Autor:
Meenu Kesarwani, Ronen Hazan, Jianxin He, YokAi Que, Yiorgos Apidianakis, Biliana Lesic, Gaoping Xiao, Valérie Dekimpe, Sylvain Milot, Eric Deziel, François Lépine, Laurence G. Rahme
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8 (2011)
Externí odkaz:
https://doaj.org/article/3ea1bcc767ac446db44f4a0a688cc6a6
Autor:
Mohammad Azhar, Zachary Kincaid, Meenu Kesarwani, Jacob Menke, Joshua Schwieterman, Sekhu Ansari, Angela Reaves, Arhama Ahmed, Rammsha Shehzad, Areeba Khan, Nuha Syed, Noor Amir, Mark Wunderlich, Tahir Latif, William Seibel, Mohammad Azam
Publikováno v:
Blood Advances. 7:1460-1476
Despite significant advancements in developing selective FMS-like tyrosine kinase 3 (FLT3) inhibitors, resistance to treatment is common even on continued therapy. Acquisition of on-target mutations or adaptation to MAPK, JAK2, and ABL signaling path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f1efb6e215ddb3ea65af4de045b2fc
https://doi.org/10.1182/bloodadvances.2022007486
https://doi.org/10.1182/bloodadvances.2022007486
Autor:
Mohammad Azam, Mohammad Azhar, Daniel T. Starczynowski, Tahir Latif, Zachary Kincaid, Meenu Kesarwani
Publikováno v:
Blood Advances. 6:1186-1192
Kinase activating mutation in FLT3 is the most frequent genetic lesion associated with poor prognosis in acute myeloid leukemia (AML). Therapeutic response to FLT3 tyrosine kinase inhibitor (TKI) therapy is dismal, and many patients relapse even afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527a97483d122c476cf442a1013ecfac
https://doi.org/10.1182/bloodadvances.2021004611
https://doi.org/10.1182/bloodadvances.2021004611
Publikováno v:
Blood. 140:9582-9583
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea7877cca29c830a015039704bba947a
https://doi.org/10.1182/blood-2022-167291
https://doi.org/10.1182/blood-2022-167291
Autor:
Mohammad Azhar, Zachary Kincaid, Meenu Kesarwani, Tahir Latif, Sekhu Ansari, William Seibel, Mohammad Azam
Publikováno v:
Blood. 140:3101-3102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3f648acf32e075f19b9c98cbd40fcc8
https://doi.org/10.1182/blood-2022-167484
https://doi.org/10.1182/blood-2022-167484
Autor:
Chuntao Zhao, Cuiqing Fan, Ashley Kuenzi Davis, Mohammad Azam, Meenu Kesarwani, Xiaoyi Chen, Cindy L. Hochstetler, Feng Zhang, Weidong Tian, Xiongwei Cai, Yi Zheng, Gang Huang, Fukun Guo, Q. Richard Lu, Zhaowei Tu, Lingli Xu
Publikováno v:
Proc Natl Acad Sci U S A
The mechanistic target of rapamycin (mTOR) is a central regulator of cell growth and an attractive anticancer target that integrates diverse signals to control cell proliferation. Previous studies using mTOR inhibitors have shown that mTOR targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8debe26a0a0895f27d2d22528eb98edf
https://doi.org/10.1073/pnas.2020102118
https://doi.org/10.1073/pnas.2020102118