Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Meenal Sinha"'
1
Akademický článek
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma
Autor: Hideho Okada, Lawrence Fong, Christine E Brown, Shilpa A Shahani, Paul R Walker, Meenal Sinha, Eric V Liu, Erin F Simonds, Edbert D Lu, Oscar Badillo, Shokoufeh Karimi, Whitney Tamaki, Chiara Rancan, Kira M Downey, Jacob Stultz, Lauren K McHenry, Nicole M Nasholm, Pavlina Chuntova, Anders Sundström, Vassilis Genoud, Leo D Wang, Fredrik J Swartling, William A Weiss, Mats Hellström
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Glioblastoma (GBM) is refractory to immune checkpoint inhibitor (ICI) therapy. We sought to determine to what extent this immune evasion is due to intrinsic properties of the tumor cells versus the specialized immune context of the brain,
Externí odkaz: https://doaj.org/article/6b195c70cb3f48339806e87479adb50b
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2
Akademický článek
Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting
Autor: Meenal Sinha, Clifford Lowell
Publikováno v: Bio-Protocol, Vol 6, Iss 22 (2016)
In this protocol, we describe the method for isolating highly pure primary alveolar epithelial type II (ATII) cells from lungs of naïve mice. The method combines negative selection for a variety of lineage markers along with positive selection for E
Externí odkaz: https://doaj.org/article/d58e733244264fec8b8a8c9678211469
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3
Akademický článek
MyD88 Shapes Vaccine Immunity by Extrinsically Regulating Survival of CD4+ T Cells during the Contraction Phase.
Autor: Huafeng Wang, Mengyi Li, Chiung Yu Hung, Meenal Sinha, Linda M Lee, Darin L Wiesner, Vanessa LeBert, Tassanee Lerksuthirat, Kevin Galles, Marulasiddappa Suresh, Anthony L DeFranco, Clifford A Lowell, Bruce S Klein, Marcel Wüthrich
Publikováno v: PLoS Pathogens, Vol 12, Iss 8, p e1005787 (2016)
Soaring rates of systemic fungal infections worldwide underscore the need for vaccine prevention. An understanding of the elements that promote vaccine immunity is essential. We previously reported that Th17 cells are required for vaccine immunity to
Externí odkaz: https://doaj.org/article/39786d3e904b4e06849cf346410a9e6d
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4
Akademický článek
FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection.
Autor: Sheena C Kerr, Gregory J Fischer, Meenal Sinha, Orla McCabe, Jonathan M Palmer, Tsokyi Choera, Fang Yun Lim, Michaela Wimmerova, Stephen D Carrington, Shaopeng Yuan, Clifford A Lowell, Stefan Oscarson, Nancy P Keller, John V Fahy
Publikováno v: PLoS Pathogens, Vol 12, Iss 4, p e1005555 (2016)
The immune mechanisms that recognize inhaled Aspergillus fumigatus conidia to promote their elimination from the lungs are incompletely understood. FleA is a lectin expressed by Aspergillus fumigatus that has twelve binding sites for fucosylated stru
Externí odkaz: https://doaj.org/article/90fc4304f59a46b1beaa1789956a5435
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5
Akademický článek
Determinants of Divergent Adaptive Immune Responses after Airway Sensitization with Ligands of Toll-Like Receptor 5 or Toll-Like Receptor 9.
Autor: Linda M Lee, Ming Ji, Meenal Sinha, Matthew B Dong, Xin Ren, Yanli Wang, Clifford A Lowell, Sankar Ghosh, Richard M Locksley, Anthony L DeFranco
Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0167693 (2016)
Excessive type 2 helper T cell responses to environmental antigens can cause immunopathology such as asthma and allergy, but how such immune responses are induced remains unclear. We studied this process in the airways by immunizing mice intranasally
Externí odkaz: https://doaj.org/article/ebe3bfb377a3495bad0dfcd6adb1291d
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6
Characteristics, Hospital Length of Stay, and Readmissions Among Individuals Undergoing Abdominal Ostomy Surgery
Autor: Laura L, Schott, Deanna, Eaves, Gary, Inglese, Meenal, Sinha
Publikováno v: Journal of Wound, Ostomy & Continence Nursing. 49:529-539
The purpose of this study was to examine patient characteristics, length of stay (LOS), hospital revisits, and complications of patients undergoing abdominal ostomy surgery.Retrospective cohort study.Data were extracted from the PINC AI Healthcare Da
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edf1af980365fd0cac74a1954f1cc86
https://doi.org/10.1097/won.0000000000000922
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7
A Real-World Comparative Effectiveness Analysis of Thromboprophylactic Use of Enoxaparin Versus Unfractionated Heparin in Abdominal Surgery Patients in a Large U.S. Hospital Database
Autor: Z M Xiao, Meenal Sinha, A. Levorsen, S. P. Veeranki, Bimal R. Shah
Publikováno v: Hosp Pharm
Introduction: Little is known about outcomes associated with enoxaparin versus unfractionated heparin (UFH) for venous thromboembolism (VTE) prophylaxis in abdominal surgery patients in U.S. clinical practice. The purpose of this study was to compare
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569f2a7df4397760d4e2aa4dcf589294
https://pubmed.ncbi.nlm.nih.gov/35521006
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9
Real-World Comparative Effectiveness and Cost Comparison of Thromboprophylactic Use of Enoxaparin versus Unfractionated Heparin in 376,858 Medically Ill Hospitalized US Patients
Autor: Meenal Sinha, Zhimin Xiao, Andrée Levorsen, S. Phani Veeranki, Bimal R. Shah
Publikováno v: American Journal of Cardiovascular Drugs
Background Venous thromboembolism (VTE) is a serious complication in medically ill inpatients. Enoxaparin or unfractionated heparin (UFH) thromboprophylaxis has been shown to reduce VTE in clinical trials; however, comparative effectiveness and diffe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8132ae0d2a2cea7ab7365b3d271d84fb
https://doi.org/10.1007/s40256-020-00456-4
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10
Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer
Autor: Sharon Ng, Meenal Sinha, Rahul Aggarwal, Terence W. Friedlander, Christopher Nguyen, Li Zhang, Sumit K. Subudhi, Brandon Chen, E Liu, Alexander Cheung, Padmanee Sharma, Kate Allaire, James P. Allison, Lawrence Fong, Matthew H. Spitzer, Eric J. Small, Jaqueline Marquez
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for Immunotherapy of Cancer
Journal for immunotherapy of cancer, vol 9, iss 5
BackgroundSipuleucel-T is a US Food and Drug Administration-approved autologous cellular immunotherapy that improves survival in patients with metastatic castration-resistant prostate cancer (mCRPC). We examined whether administering ipilimumab after
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5d0726f148b3ed35627fd24c6ab7f1
https://jitc.bmj.com/content/9/5/e002254.full
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