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pro vyhledávání: '"Meenal Francis"'
Autor:
Meenal Francis, Smitha Bhaskar, Saarwani Komanduri, Preethi Sheshadri, Jyothi Prasanna, Anujith Kumar
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106771- (2023)
Summary: Loss of insulin-secreting β-cells in diabetes may be either due to apoptosis or dedifferentiation of β-cell mass. The ubiquitin-proteasome system comprising E3 ligase and deubiquitinases (DUBs) controls several aspects of β-cell functions
Externí odkaz:
https://doaj.org/article/e4bf2c1186704b0691f263f5a0c93098
Publikováno v:
Current Protein & Peptide Science. 23:602-618
Abstract: Impairment in the function of insulin-producing pancreatic β-cells is a hallmark of both type 1 and 2 diabetes (T1D/T2D). Despite over a century of effort, there is still no precise treatment regimen available for acute diabetes. Enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af8eef0e982f39e32e3c148da2d7ab1
https://doi.org/10.2174/1389203723666220422092023
https://doi.org/10.2174/1389203723666220422092023
Diabetes is a metabolic disease caused majorly due to loss of insulin secreting β-cells. Along with apoptosis, recent reports revealed dedifferentiation to be the added reason for the reduced β-cell mass. The Ubiquitin Proteasome system comprising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc83f12a313979d3bae2349186a45b65
https://doi.org/10.1101/2022.10.14.512247
https://doi.org/10.1101/2022.10.14.512247
Autor:
Anujith Kumar, Meenal Francis, Akshaya Ashok, Ashwini Ashwathnarayan, Shreetama Banerjee, Jyothi Prasanna
Publikováno v:
Current diabetes reviews.
Abstract: Distinct molecular processes are engaged during histogenesis, and Epithelial to Mesenchymal Transition (EMT) is one of the key evolutionarily conserved processes that facilitates organ development. Molecular pathways governing EMT are embed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a7ebdc8f3df42b00c4b12ac2a4f02a
https://pubmed.ncbi.nlm.nih.gov/35598235
https://pubmed.ncbi.nlm.nih.gov/35598235