Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Meenakumari, Muthuramalingam"'
Autor:
Shoichi Tachiyama, Ryan Skaar, Yunjie Chang, Brittany L. Carroll, Meenakumari Muthuramalingam, Sean K. Whittier, Michael L. Barta, Wendy L. Picking, Jun Liu, William D. Picking
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Shigella flexneri, causative agent of bacillary dysentery (shigellosis), uses a type III secretion system (T3SS) as its primary virulence factor. The T3SS injectisome delivers effector proteins into host cells to promote entry and create an important
Externí odkaz:
https://doaj.org/article/0aaf6a10cbf3414396bc596f44958524
Autor:
Jessica R. Ames, Meenakumari Muthuramalingam, Tamiko Murphy, Fares Z. Najar, Christina R. Bourne
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 10, Pp n/a-n/a (2019)
Abstract Toxin–antitoxin (TA) systems are found on both chromosomes and plasmids. These systems are unique in that they can confer both fatal and protective effects on bacterial cells—a quality that could potentially be harnessed given further un
Externí odkaz:
https://doaj.org/article/7ce0c4d83c3d46e081530d5202136c2f
Publikováno v:
Microorganisms, Vol 9, Iss 2, p 451 (2021)
Shigella comprises four species of human-restricted pathogens causing bacillary dysentery. While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion system (T3SS) is its primary virulence factor. The Shigella T3SS
Externí odkaz:
https://doaj.org/article/c3608c232ccf473cbd0448bf587b7e3e
Autor:
Michael L. Barta, Bo Hu, Jun Liu, Meenakumari Muthuramalingam, William D. Picking, Yunjie Chang, Shoichi Tachiyama, Wendy L. Picking
Publikováno v:
Journal of Biological Chemistry. 294:19184-19196
Many Gram-negative bacteria use type III secretion systems (T3SSs) to inject virulence effector proteins into eukaryotic cells. The T3SS apparatus (T3SA) is structurally conserved among diverse bacterial pathogens and consists of a cytoplasmic sortin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eb5fea5999e8dd2a2570b181382cabc
https://doi.org/10.1074/jbc.ra119.009125
https://doi.org/10.1074/jbc.ra119.009125
Autor:
Jessica R. Ames, Christina R. Bourne, John C. White, Tamiko Murphy, Meenakumari Muthuramalingam
Publikováno v:
Molecular Microbiology. 111:441-454
Toxin-antitoxin systems are mediators of diverse activities in bacterial physiology. For the ParE-type toxins, their reported role of gyrase inhibition utilized during plasmid-segregation killing indicates they are toxic. However, their location thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7abb846f9e8491674f729c0230154e18
https://doi.org/10.1111/mmi.14165
https://doi.org/10.1111/mmi.14165
Autor:
William D. Picking, Wendy L. Picking, Jun Liu, Meenakumari Muthuramalingam, Michael L. Barta, Sean K. Whittier, Yunjie Chang, Shoichi Tachiyama, Ryan Skaar, Brittany L. Carroll
Shigella flexneri, causative agent of bacillary dysentery (shigellosis), uses a type III secretion system (T3SS) as its primary virulence factor. The T3SS injectisome delivers effector proteins into host cells to promote entry and create an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0382a017dcac3aab3c059d1b579c28b
https://doi.org/10.1101/2021.05.13.444006
https://doi.org/10.1101/2021.05.13.444006
Publikováno v:
Microorganisms, Vol 9, Iss 451, p 451 (2021)
Microorganisms
Microorganisms
Shigella comprises four species of human-restricted pathogens causing bacillary dysentery. While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion system (T3SS) is its primary virulence factor. The Shigella T3SS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38350cd7d3e411473101d79e47c6495
https://www.mdpi.com/2076-2607/9/2/451
https://www.mdpi.com/2076-2607/9/2/451
Publikováno v:
Toxins, Vol 8, Iss 7, p 214 (2016)
Toxin-antitoxin (TA) modules are bacterial regulatory switches that facilitate conflicting outcomes for cells by promoting a pro-survival phenotypic adaptation and/or by directly mediating cell death, all through the toxin activity upon degradation o
Externí odkaz:
https://doaj.org/article/3a2c64c898634cc3960dc758eea1cd56
Autor:
Kevin P. Battaile, Meenakumari Muthuramalingam, William D. Picking, Shoichi Tachiyama, David K. Johnson, Scott Lovell, Wendy L. Picking, Sean K. Whittier
Many Gram-negative bacterial pathogens use type III secretion systems (T3SS) to inject effector proteins into eukaryotic cells to subvert normal cellular functions. The T3SS apparatus (injectisome) shares a common overall architecture in all systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6393333d5c4a66becec212ff83b2447c
https://doi.org/10.1101/2020.09.22.308627
https://doi.org/10.1101/2020.09.22.308627
Autor:
Meenakumari Muthuramalingam, Shoichi Tachiyama, William D. Picking, Brian V. Geisbrecht, Kevin P. Battaile, Kasra X. Ramyar, Cecilia E. Villanueva, Wendy L. Picking, Michael L. Barta, Olivia Arizmendi, Scott Lovell
Publikováno v:
Protein Science. 27:1392-1406
Bacterial type III secretion systems (T3SS) are used to inject proteins into mammalian cells to subvert cellular functions. The Shigella T3SS apparatus (T3SA) is comprised of a basal body, cytoplasmic sorting platform and exposed needle with needle "
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e004bea7446c816b466a935f4764e524
https://doi.org/10.1002/pro.3428
https://doi.org/10.1002/pro.3428